Last update 04 Nov 2024

Etidronate Disodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(1-hydroxy-ethylidene)diphosphonic acid, (1-Hydroxyethylene)diphosphonic acid, (1-Hydroxyethylidene)bis(phosphonic acid)
+ [35]
Mechanism
Bone resorption factor inhibitors
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (US), Orphan Drug (EU)
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Structure

Molecular FormulaC2H8Na2O7P2
InChIKeyFCBYKAIUKRZZGW-UHFFFAOYSA-N
CAS Registry7414-83-7

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Ossification, Heterotopic
JP
28 Sep 1990
Osteoporosis
US
01 Sep 1977
Osteitis Deformans
US
01 Sep 1977
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Fahr's DiseasePhase 2
NL
03 Apr 2023
HEM DysplasiaPhase 2
NL
03 Apr 2023
ABCC6 deficiencyPreclinical
EU
11 Oct 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
7
MRI Scan+Etidronate
zabvrsugvb(qlpklhjgws) = qldhaqtpwi uhzjypzrta (wnhzwsmfgz, vvddruwilp - tsmccwutxm)
-
04 Oct 2022
Not Applicable
Chronic glomerulonephritis | Glucocorticoid-induced osteoporosis
N-terminal telopeptide of type I collagen (NTx) | uncarboxylated osteocalcin (ucOC)
43
nbctjmrifb(xkmnqqkoxf) = There were no significant differences in BMD between these groups during the study tsdibidueg (pcxhsbndxi )
Positive
05 Nov 2013
Not Applicable
50
HRT
ijjrdmuxib(vfzzahaeco) = xrvlzzqeqp ycktetyavp (jkwnaxtkii )
-
01 Feb 2009
ijjrdmuxib(vfzzahaeco) = zpfekuffan ycktetyavp (jkwnaxtkii )
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Approval

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Regulation

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