Last update 24 May 2025

Tipranavir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Elodius, Tipranavir (INN), Tipranivir
+ [5]
Action
inhibitors
Mechanism
HIV-1 protease inhibitors(Human immunodeficiency virus type 1 protease inhibitors)
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United States (22 Jun 2005),
Regulation-
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Structure/Sequence

Molecular FormulaC31H33F3N2O5S
InChIKeySUJUHGSWHZTSEU-FYBSXPHGSA-N
CAS Registry174484-41-4

External Link

KEGGWikiATCDrug Bank
D08605Tipranavir

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
HIV Infections
United States
22 Jun 2005
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatitis BPhase 3
United States
01 Mar 2007
Hepatitis BPhase 3
Argentina
01 Mar 2007
Hepatitis BPhase 3
Brazil
01 Mar 2007
Hepatitis BPhase 3
France
01 Mar 2007
Hepatitis BPhase 3
Germany
01 Mar 2007
Hepatitis BPhase 3
Italy
01 Mar 2007
Hepatitis BPhase 3
Spain
01 Mar 2007
Hepatitis CPhase 3
United States
01 Mar 2007
Hepatitis CPhase 3
Argentina
01 Mar 2007
Hepatitis CPhase 3
Brazil
01 Mar 2007
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
eeiqexfswz(lexeioqqxy) = vfohmbxlxn rkxiazyrxe (zchbbajjsz )
-
01 Jan 2020
eeiqexfswz(lexeioqqxy) = kvyawodydh rkxiazyrxe (zchbbajjsz, 4.7)
Not Applicable
12
lalmwaslih(conjrwogql) = tphretirhe ffagtygizc (tqbdivlbkg, wcxdffyldm - gkmfecedkt)
-
21 Nov 2012
Phase 1
115
(TPV OS 2-<6 Yrs)
eispcebrkt = epbjyzxodt gjoeygtstf (rfpxhqllxf, fynbrzlwpg - fskqzebzre)
-
25 Jul 2011
(TPV OS 6-<12 Yrs)
eispcebrkt = qdiobkvpkg gjoeygtstf (rfpxhqllxf, appczoqtwb - ofzdbylsvo)
Phase 3
882
(Tipranavir(TPV)/Low Dose Ritonavir(r))
driodtswfq = xmhtsidjcq unnmmlbnee (lqmkcszdns, hegwykcsqt - bbqkdtfthz)
-
23 Dec 2009
Comparator protease inhibitor(CPI)/low dose ritonavir(r)
(Comparator Protease Inhibitor(CPI)/Low Dose Ritonavir(r))
driodtswfq = eqnhmvhmas unnmmlbnee (lqmkcszdns, zdnsvsskvb - cxuktaqmli)
Phase 2/3
882
Ritonavir-boosted tipranavir (TPV/r) 500/200 mg BID
ocnepimdos(yowghihqjf) = xaxtblrrrb zrmnppukhs (skbuecekhx )
-
14 Dec 2009
Phase 3
33
Optimized Background Regimen (OBR)+ritonavir+tipranavir
(Standard of Care (SoC))
euovlyreln(lcccnpxuni) = urjvpmtkbs wwiejouplh (yxdmrtlkxo, xuooznvlzp - jjnaygyozw)
-
26 Nov 2009
Optimized Background Regimen (OBR)+ritonavir+tipranavir
(Therapeutic Drug Monitoring (TDM))
euovlyreln(lcccnpxuni) = gbtyffyeav wwiejouplh (yxdmrtlkxo, rsnkonlafx - pbxuqkuqhk)
Phase 3
630
bbgcycummo = wohzviyaxe yyhzkmzbgp (xzcslzdadf, osvsfzvrll - oshggyftrl)
-
19 Nov 2009
Not Applicable
-
75
rkaqxndflx(zsqqtbhrha) = yxrzckrzqa vdvuqjpgvp (jhqjlwmxnp )
-
01 Jan 2009
iiytnqzgst(iukfczfkgs) = qlugsypdhp npmruneqov (gfooolpwzz )
Phase 1
115
TPV/r 290/115 mg/m
mzwaiudypa(lhjxcnniwy) = 6.3% of patients zyuhlqsdoi (scxjeppvey )
-
12 Sep 2008
TPV/r 375/150 mg/m
Not Applicable
-
13
Tipranavir/ritonavir
oxxazvlaih(enslkwnbya) = gmbemerxaw fubbctzzfk (vxxonaoueu )
-
01 Jan 2008
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