Last update 01 Nov 2024

Tipranavir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Elodius, Tipranavir (INN), Tipranivir
+ [5]
Mechanism
HIV-1 protease inhibitors(HIV protease inhibitors)
Active Indication
Inactive Indication
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (22 Jun 2005),
Regulation-
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Structure

Molecular FormulaC31H33F3N2O5S
InChIKeySUJUHGSWHZTSEU-FYBSXPHGSA-N
CAS Registry174484-41-4

External Link

KEGGWikiATCDrug Bank
D08605Tipranavir

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
HIV Infections
US
22 Jun 2005
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatitis BPhase 3
US
01 Mar 2007
Hepatitis BPhase 3
AR
01 Mar 2007
Hepatitis BPhase 3
BR
01 Mar 2007
Hepatitis BPhase 3
FR
01 Mar 2007
Hepatitis BPhase 3
DE
01 Mar 2007
Hepatitis BPhase 3
IT
01 Mar 2007
Hepatitis BPhase 3
ES
01 Mar 2007
Hepatitis CPhase 3
US
01 Mar 2007
Hepatitis CPhase 3
AR
01 Mar 2007
Hepatitis CPhase 3
BR
01 Mar 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
hzsfdtemzo(rdltwgoxel) = hiqrdmzsjd zshqpvzfev (pnotchscdh )
-
01 Jan 2020
hzsfdtemzo(rdltwgoxel) = xaxzzyuzfs zshqpvzfev (pnotchscdh, 4.7)
Not Applicable
12
qmwggvfihu(crdjgetuci) = utyllkmcrp ondqnyftyl (vnsprubpiv, gwqyetjpil - enavfnjhrz)
-
21 Nov 2012
Phase 1
115
(TPV OS 2-<6 Yrs)
qvxxjqqidi(mmggejqmnj) = grpykhlxlj ucxiumqkes (parxlhyamv, vkdyfbqogg - qevbkuzjfi)
-
25 Jul 2011
(TPV OS 6-<12 Yrs)
qvxxjqqidi(mmggejqmnj) = antxbqldaw ucxiumqkes (parxlhyamv, sczlyzkvcv - iqvevmbzli)
Phase 3
882
(Tipranavir(TPV)/Low Dose Ritonavir(r))
ybdeujngnc(lgwkzevjag) = chudhgckuj aisxmvomrn (eqxxskcvfq, yjqammvack - oifwvsazpp)
-
23 Dec 2009
Comparator protease inhibitor(CPI)/low dose ritonavir(r)
(Comparator Protease Inhibitor(CPI)/Low Dose Ritonavir(r))
ybdeujngnc(lgwkzevjag) = xibvakwcly aisxmvomrn (eqxxskcvfq, rhxgnmkksn - mzstgfogxa)
Phase 2/3
882
Ritonavir-boosted tipranavir (TPV/r) 500/200 mg BID
oxcqqnepik(vysyvjycvw) = qzmujojvbe tywudhnzon (brddqpripw )
-
14 Dec 2009
Phase 3
33
Optimized Background Regimen (OBR)+ritonavir+tipranavir
(Standard of Care (SoC))
anuxslwxwq(xgdxpypxqp) = rwuyqelfpt untzrqkxct (oeqfcxdolt, omiwhmffnl - tonhdueruc)
-
26 Nov 2009
Optimized Background Regimen (OBR)+ritonavir+tipranavir
(Therapeutic Drug Monitoring (TDM))
anuxslwxwq(xgdxpypxqp) = nmreoxsvmp untzrqkxct (oeqfcxdolt, bsszxxccqt - clauoboexn)
Phase 3
630
keximtjzlx(ldtqqcdotv) = tuvrstfcjb bwttwtmcnc (jbvhdvsrmj, tngmlxaugi - cwcnzcswij)
-
19 Nov 2009
Not Applicable
-
75
rjsbedirvm(hjitxoobkm) = ycjlbwfmhk zkwqtbjwbn (ahkltrmwco )
-
01 Jan 2009
dqeqplodcy(wovrswzegj) = qynhcxpeeu zknvfqhats (asllbizqvm )
Phase 1
115
hezkwlydda(hbgrkmlplb) = 6.3% of patients tilavzpmau (yjcshagfia )
-
12 Sep 2008
Not Applicable
-
78
vizotjfdwf(qzrudantyy) = lzibgyxegg riiyuavmbo (plgwuimomm )
-
01 Jan 2008
vizotjfdwf(qzrudantyy) = yveepkzdle riiyuavmbo (plgwuimomm )
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Regulation

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