Last update 20 Mar 2025

Ibrilatazar

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Sodium 2-hydroxylinoleate
+ [2]
Target
Action
agonists
Mechanism
PPARα/γ agonists(PPAR alpha/gamma agonists)
Originator Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationSpecial Review Project (China), Orphan Drug (European Union)
Login to view timeline

Structure/Sequence

Molecular FormulaC18H32O3
InChIKeyAFDSETGKYZMEEA-HZJYTTRNSA-N
CAS Registry57818-44-7

External Link

KEGGWikiATCDrug Bank
---

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
NeuroblastomaPhase 2
Spain
18 Jul 2023
Pancreatic CancerPhase 2
European Union
30 Jan 2022
Pancreatic CancerPhase 2
European Union
30 Jan 2022
Metastatic Pancreatic CancerPhase 2
Spain
26 Apr 2021
Squamous Cell CarcinomaPhase 2
China
29 Oct 2018
Squamous non-small cell lung cancerPhase 2
Spain
01 Dec 2016
Advanced cancerPhase 2
Spain
01 Feb 2014
Advanced Malignant Solid NeoplasmPhase 2
Spain
01 Feb 2014
Endometrial CarcinomaPhase 2
Spain
-
Lung CancerPhase 2
Spain
-
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
51
Ibrilatazar (ABTL0812) + Carboplatin/Paclitaxel
(The phase 1 part)
-
Positive
22 Jul 2024
Ibrilatazar (ABTL0812) + Carboplatin/Paclitaxel
(khghfbuxiy) = simoqzvrjr izznvilczo (afkxilfoxt )
Phase 2
40
ABTL0812+Paclitaxel+Carboplatin
(ldgchtiges) = zqjxmxropv bejzhqftiv (lummcfblce, 34.2 - 65.9)
Positive
26 May 2023
Not Applicable
22
(tnahlrxymg) = pfxdpkurgc gnjuexgivy (rmavjnrrov, 32.2 - 75.6)
-
29 Jan 2021
Phase 2
42
(iqtdttghks) = bnklbvvxil thobfhywvf (bmeuexeryq, 46 - 80)
Positive
17 Sep 2020
Phase 1
21
Paclitaxel+Carboplatin+ABTL 0812
(ymqshabjad) = neutrophil count decreased (43%), nausea (24%), fatigue (19%), anemia, vomiting, dyspepsia, platelet count decreased, arthralgia and neurotoxicity (10% each) svdrqrlsbg (oazihsirce )
Positive
01 Jun 2019
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free