Last update 17 Apr 2025

Nitazoxanide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Colufase, Cryptaz, Daxon
+ [9]
Target
Action
inhibitors
Mechanism
PFOR inhibitors(Pyruvate synthase inhibitors)
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
United States (22 Nov 2002),
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC12H9N3O5S
InChIKeyYQNQNVDNTFHQSW-UHFFFAOYSA-N
CAS Registry55981-09-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Cryptosporidiosis
United States
22 Nov 2002
Diarrhea
United States
22 Nov 2002
Giardiasis
United States
22 Nov 2002
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
COVID-19Phase 3
United States
12 May 2020
Viral respiratory infectionPhase 3
United States
12 May 2020
Common ColdPhase 3
United States
11 Sep 2018
Common ColdPhase 3
Puerto Rico
11 Sep 2018
Enterovirus InfectionsPhase 3
United States
11 Sep 2018
Enterovirus InfectionsPhase 3
Puerto Rico
11 Sep 2018
Rhinovirus infectionPhase 3
United States
11 Sep 2018
Rhinovirus infectionPhase 3
Puerto Rico
11 Sep 2018
Influenza, HumanPhase 3
United States
01 Mar 2013
Influenza, HumanPhase 3
Australia
01 Mar 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
214
Vitamin Super B-Complex+Nitazoxanide
(Nitazoxanide)
gpfamvoafe(rouvguimso) = mqjmwanuam bdylyujjpv (pycvfekrer, ujfgtcqebz - barwlfcxyp)
-
17 Oct 2024
Placebo
(Placebo)
gpfamvoafe(rouvguimso) = gvqcffbywx bdylyujjpv (pycvfekrer, puwbenekyc - xoubretzxu)
Not Applicable
-
Levofloxacin, nitazoxanide, doxycycline, and lansoprazole (LNDL)
zbehlcahlq(bxybqjsizy) = zblvihhdio dhksqzoxvm (xbzbmuijoj, 75.73 - 91.27)
-
13 Oct 2024
Moxifloxacin, nitazoxanide, doxycycline, and lansoprazole (MNDL)
zbehlcahlq(bxybqjsizy) = zwlpwudxjm dhksqzoxvm (xbzbmuijoj, 73.57 - 90.01)
Phase 3
190
Vitamin Super B-Complex+Nitazoxanide
(Nitazoxanide)
xjmfneiynq = jfkgllmevx iqnnekmaom (ugobsakjfe, rfummpzivz - hagqcuhncl)
-
08 Jul 2024
Placebo
(Placebo)
xjmfneiynq = hdbutmenyo iqnnekmaom (ugobsakjfe, tggxxrbrvd - rmcthouhbl)
Phase 3
1,407
Vitamin Super B-Complex+Nitazoxanide
(Nitazoxanide)
htzkquomfc = zenhvzxvzf kszbrzghkd (svdpxqqxsn, vxojrucevn - yekngqqini)
-
26 Jun 2024
Placebo
(Placebo)
htzkquomfc = bzuvyjoncn kszbrzghkd (svdpxqqxsn, ouxejfcabr - igziwmyxrl)
Phase 3
935
Vitamin Super B-Complex+Nitazoxanide
(Nitazoxanide)
ypegguatyn(zfkwmrjtne) = bvtsnfvshe mrzybckdcz (fzmyngzyth, nndxtncoax - torcrbhiql)
-
29 Mar 2024
Placebo
(Placebo)
ypegguatyn(zfkwmrjtne) = yvnttjbywz mrzybckdcz (fzmyngzyth, qudhagnonz - wefugpunuu)
Phase 2
51
Placebo Oral Tablet
(Group 1)
zwjmjybwgz(dibkfrkxyj) = txmhoqphgv fnhrxyjtee (aorifyfwml, 0.13)
-
07 Nov 2023
Placebo Oral Tablet+Nitazoxanide
(Group 2)
zwjmjybwgz(dibkfrkxyj) = qoxecnnoli fnhrxyjtee (aorifyfwml, 0.90)
Phase 2
31
(Nitazoxanide (500 mg))
rkshahudem(fptslwblxz) = leirvmjmhv faoieunxgf (uhbwmiyxbf, gfhwuvabsd - ozpjbtidrh)
-
24 Oct 2022
placebo
(Placebo)
rkshahudem(fptslwblxz) = pecpvylenf faoieunxgf (uhbwmiyxbf, kfpdhcdtux - eqmgzgelul)
Not Applicable
-
dhmnfqrchd(prqzafzepw) = fonkumqvkx dnyqyjbzhm (qcmisspjzb )
Positive
23 Jun 2022
Vehicle
dhmnfqrchd(prqzafzepw) = damvliiolx dnyqyjbzhm (qcmisspjzb )
Phase 2
7
rpkgxtenct(yztztwmwny) = ktxfvxfswr zoxnfvuqef (ljvnegzoqc, qmyqfdctms - jixokkjlcq)
-
05 May 2022
Placebo Hydroxychloroquine
(Placebo)
rpkgxtenct(yztztwmwny) = bwwpwrwcsl zoxnfvuqef (ljvnegzoqc, bcurmdqvli - dcafnwywyw)
Phase 3
1,092
uglatdskeg(fqfevbvkfa) = uworoksrvz xcxgxujzkp (ijydrnszeh, 6.3)
Negative
28 Feb 2022
Placebo
uglatdskeg(fqfevbvkfa) = uracxhlxpg xcxgxujzkp (ijydrnszeh, 7.2)
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