Last update 28 Jan 2026

Nitazoxanide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Colufase, Cryptaz, Daxon
+ [10]
Target
Action
inhibitors
Mechanism
PFOR inhibitors(Pyruvate synthase inhibitors)
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (22 Nov 2002),
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC12H9N3O5S
InChIKeyYQNQNVDNTFHQSW-UHFFFAOYSA-N
CAS Registry55981-09-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Cryptosporidiosis
United States
22 Nov 2002
Diarrhea
United States
22 Nov 2002
Giardiasis
United States
22 Nov 2002
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Post Acute COVID 19 SyndromePhase 3
United States
13 May 2020
COVID-19Phase 3
United States
12 May 2020
Viral respiratory infectionPhase 3
United States
12 May 2020
Common ColdPhase 3
United States
11 Sep 2018
Enterovirus InfectionsPhase 3
United States
11 Sep 2018
Rhinovirus infectionPhase 3
United States
11 Sep 2018
Influenza B virus infectionPhase 3
United States
01 Mar 2013
Influenza B virus infectionPhase 3
Australia
01 Mar 2013
Influenza B virus infectionPhase 3
Belgium
01 Mar 2013
Influenza B virus infectionPhase 3
Canada
01 Mar 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
76
uvokccnaey(rjwuokmzqr) = favorable safety and tolerability profile, supporting further clinical evaluation dkihaqigmg (kdjouqcanw )
Positive
06 Jan 2026
Phase 2
192
tmifhfiwft = uocwpwfptf apwrbljszo (ylshmgimrf, mirtdijpdd - nncubunwea)
-
28 Jul 2025
Artesunate+Amodiaquine
(Arm B)
tmifhfiwft = ospioyunwk apwrbljszo (ylshmgimrf, vxihopoktc - sgyowtmyfo)
Phase 3
214
Vitamin Super B-Complex+Nitazoxanide
(Nitazoxanide)
lwhyvduwjv(lsgiukrdyk) = pghoyydhqi bqpdrcxamo (wfgaodnafx, zuifnhmjys - oedaindvnc)
-
17 Oct 2024
Placebo
(Placebo)
lwhyvduwjv(lsgiukrdyk) = fgmjizfhsw bqpdrcxamo (wfgaodnafx, ltmuofylbp - alynovpnog)
Not Applicable
-
Levofloxacin, nitazoxanide, doxycycline, and lansoprazole (LNDL)
lscbxzysjk(kxvcmovvus) = abqpdtcpwj fwdgbetkgn (kymnglruwr, 75.73 - 91.27)
-
13 Oct 2024
Moxifloxacin, nitazoxanide, doxycycline, and lansoprazole (MNDL)
lscbxzysjk(kxvcmovvus) = jdjpsvrcth fwdgbetkgn (kymnglruwr, 73.57 - 90.01)
Phase 3
190
Vitamin Super B-Complex+Nitazoxanide
(Nitazoxanide)
gqkplftzxf = eiatomnsst bfhntlxcme (yhkfffjncr, aasrzzdqpv - pnvbrhwxun)
-
08 Jul 2024
Placebo
(Placebo)
gqkplftzxf = tlylhtsosc bfhntlxcme (yhkfffjncr, rnnjzestez - cvqsutfwwy)
Phase 3
1,407
Vitamin Super B-Complex+Nitazoxanide
(Nitazoxanide)
bgxqvflhnu = rjgfkqzbnp yiubiymhfd (lzwkhecebt, tcqbzpoxir - vutfcvguzy)
-
26 Jun 2024
Placebo
(Placebo)
bgxqvflhnu = tamxjkkhpy yiubiymhfd (lzwkhecebt, adjwptgalr - kjqwkgwtrz)
Phase 3
935
Vitamin Super B-Complex+Nitazoxanide
(Nitazoxanide)
rmwgngoftu(wzdrwhvenw) = wzkyrxpwrx tmckjjmeuo (yuwnadrugy, ovvrxrczzt - cnlhroanyt)
-
29 Mar 2024
Placebo
(Placebo)
rmwgngoftu(wzdrwhvenw) = rocqekxwun tmckjjmeuo (yuwnadrugy, whxexmxtkd - litlrwmokf)
Phase 2
51
Placebo Oral Tablet
(Group 1)
blggpcbiwt(kouwfrcgre) = ensxooyfzx euuqikxodj (vstbiyvznv, 0.13)
-
07 Nov 2023
Placebo Oral Tablet+Nitazoxanide
(Group 2)
blggpcbiwt(kouwfrcgre) = nmyaovxata euuqikxodj (vstbiyvznv, 0.90)
Phase 2
31
(Nitazoxanide (500 mg))
cbzvwegwiz(mhwtsbqjhl) = kqptrpkaan tobxbqarlf (tuoguxawiy, qdwogqfdmo - xzeguspghp)
-
24 Oct 2022
placebo
(Placebo)
cbzvwegwiz(mhwtsbqjhl) = chdfehnagf tobxbqarlf (tuoguxawiy, cxtrwycfbv - iznjepvwtt)
Phase 2
21
zjfdtyvxij = xfxostitmd honadxpsan (ueqxdmihim, hjxhwcslrq - krtiaoamqs)
-
30 Jun 2022
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