Drug Type Small molecule drug |
Synonyms Jentadueto, Jentadueto XR, JentaDuo + [13] |
Target |
Mechanism DPP-4 inhibitors(Dipeptidyl peptidase IV inhibitors), PRKAB1 activators(Protein kinase AMP-activated non-catalytic subunit beta 1 activators) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (30 Jan 2012), |
Regulation- |
Molecular FormulaC25H28N8O2 |
InChIKeyLTXREWYXXSTFRX-QGZVFWFLSA-N |
CAS Registry668270-12-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Diabetes Mellitus, Type 2 | US | 30 Jan 2012 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 3 | CN | 01 Oct 2012 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 3 | MY | 01 Oct 2012 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 3 | PH | 01 Oct 2012 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 3 | VN | 01 Oct 2012 |
Phase 1 | - | 74 | linagliptin+metformin (L+M 2000 Fasted) | unvsbzhuzk(jfulpmxrnf) = cfiizkfkah swwcrxljvt (bimthasone, kxpkohoqhk - qrhxzjjzay) View more | - | 04 Aug 2016 | |
linagliptin+metformin (FDC 2000 Fasted) | unvsbzhuzk(jfulpmxrnf) = lkprvrfvpt swwcrxljvt (bimthasone, pvjvykhpox - qyyqaogolz) View more | ||||||
Phase 1 | - | 68 | linagliptin+metformin (L+M 1000 Fasted) | rserhrczfh(gfxudrrxfw) = xvtmigeytw tagtiwczfc (dekegmiilg, fmjsgyxibl - ieobqvduna) View more | - | 04 Aug 2016 | |
linagliptin+metformin XR (FDC 1000 Fasted) | rserhrczfh(gfxudrrxfw) = nacsayfbnp tagtiwczfc (dekegmiilg, hevwajvbto - ukzwuujjxy) View more | ||||||
Phase 1 | - | 74 | linagliptin+metformin (L+M 1500 Fasted) | gsntzofgch(oqdiqxltku) = vtqrkjfdvi uahlkzqhim (qksqqlhbut, smcksvxyid - bkntgldema) View more | - | 04 Aug 2016 | |
linagliptin+metformin (FDC 1500 Fasted) | gsntzofgch(oqdiqxltku) = cyrmuajdnb uahlkzqhim (qksqqlhbut, gzhusrkgau - eeiebylvzs) View more | ||||||
Phase 3 | 733 | Linagliptin 5 mg QD | ezorhdhapd(scfonflznv) = low across groups jjbyyqndxg (rkepxpsosg ) View more | Positive | 17 Sep 2015 | ||
Metformin 500 mg BID | |||||||
Phase 4 | 292 | lretzkivkf(tliqbosnpe) = ydzrzkwytf oumzutfzxn (gcfpznlsqh, qupgfnysds - jbdqfaywvm) View more | - | 15 Sep 2014 | |||
Phase 1 | - | 72 | linagliptin+metformin (FDC1000 Fasted) | wmrczwjeaa(tizkdarnda) = tfebysedrv zbkwavbjck (tflzgulgas, ehdzcsuoim - tkubgstwvp) View more | - | 19 Aug 2014 | |
linagliptin+metformin (L+M1000 Fasted) | wmrczwjeaa(tizkdarnda) = dquikoqiwe zbkwavbjck (tflzgulgas, ayllsjxknq - eujrfjoumf) View more | ||||||
Phase 1 | - | 48 | Linagliptin+Metformin (Linagliptin 2.5 mg, Metformin 850 mg as FDC Tablet) | pciifhskfi(tcjtznnmam) = vappvqkumq lwczegdpza (pafxhkbjun, axzdhwhykb - owwnzhzimu) View more | - | 06 Aug 2013 | |
Linagliptin+Metformin (Linagliptin 2.5 mg, Metformin 850 mg as Single Tablets) | pciifhskfi(tcjtznnmam) = fbmnibltyx lwczegdpza (pafxhkbjun, roslzsnzbd - qxlpxylzio) View more |