Drug Type siRNA |
Synonyms SLN 124, SLN-124, SLN124 |
Target |
Action inhibitors |
Mechanism TMPRSS6 inhibitors(Transmembrane protease serine 6 inhibitors), RNA interference |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
RegulationFast Track (United States), Orphan Drug (United States), Rare Pediatric Disease (United States), Orphan Drug (European Union) |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Polycythemia Vera | Phase 2 | United States | 26 Jan 2023 | |
Polycythemia Vera | Phase 2 | Australia | 26 Jan 2023 | |
Polycythemia Vera | Phase 2 | Bulgaria | 26 Jan 2023 | |
Polycythemia Vera | Phase 2 | Malaysia | 26 Jan 2023 | |
Polycythemia Vera | Phase 2 | Poland | 26 Jan 2023 | |
Thalassemia | Phase 1 | Germany | 14 Apr 2021 | |
Thalassemia | Phase 1 | Israel | 14 Apr 2021 | |
Thalassemia | Phase 1 | Italy | 14 Apr 2021 | |
Thalassemia | Phase 1 | Jordan | 14 Apr 2021 | |
Thalassemia | Phase 1 | Malaysia | 14 Apr 2021 |
NCT04559971 (Pubmed) Manual | Phase 1 | - | 24 | pnqalpfajy(vmmgbmutbg) = none xwapvognkg (upxaguszuo ) View more | Positive | 01 Sep 2023 | |
Placebo | |||||||
Phase 1 | 24 | jepvywfjyr(liasrmptyp) = twnvayitov fvqtazplkw (izgtgdwgrm ) | Positive | 29 Sep 2022 |