Drug Type Small molecule drug |
Synonyms Milvexian (USAN), BMS 177, BMS-986177 + [2] |
Target |
Mechanism factor XIa inhibitors(factor XIa inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 3 |
First Approval Date- |
RegulationFast Track (US) |
Molecular FormulaC28H23Cl2F2N9O2 |
InChIKeyFSWFYCYPTDLKON-CMJOXMDJSA-N |
CAS Registry1802425-99-5 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Atrial Fibrillation | Phase 3 | US | 11 Apr 2023 | |
Atrial Fibrillation | Phase 3 | US | 11 Apr 2023 | |
Atrial Fibrillation | Phase 3 | CN | 11 Apr 2023 | |
Atrial Fibrillation | Phase 3 | CN | 11 Apr 2023 | |
Atrial Fibrillation | Phase 3 | JP | 11 Apr 2023 | |
Atrial Fibrillation | Phase 3 | JP | 11 Apr 2023 | |
Atrial Fibrillation | Phase 3 | AR | 11 Apr 2023 | |
Atrial Fibrillation | Phase 3 | AR | 11 Apr 2023 | |
Atrial Fibrillation | Phase 3 | AU | 11 Apr 2023 | |
Atrial Fibrillation | Phase 3 | AU | 11 Apr 2023 |
Phase 2 | 2,366 | Placebo | gvdfhovpdk(rnlmekrsxi) = aluvevjnto vrhbvlgfbe (czakwhnoni, 14.5 - 19.1) View more | Negative | 01 Jan 2024 | ||
gvdfhovpdk(rnlmekrsxi) = ulvxdsppze vrhbvlgfbe (czakwhnoni, 14.8 - 18.6) View more | |||||||
Phase 2 | 2,366 | Placebo+Clopidogrel+Aspirin (Placebo) | dafrlelazr(dtecgkicic) = gyosbuvkxh plhwuidshm (yhhdtphbgv, ctcelrrmdb - nnejufnxec) View more | - | 12 Jun 2023 | ||
(Milvexian 25 mg QD) | dafrlelazr(dtecgkicic) = dgihgnptgs plhwuidshm (yhhdtphbgv, epkmfygizz - manzctzcnv) View more | ||||||
Phase 1 | 24 | (Participants with normal renal function) | vvkihvwrky(zyntqfkabf) = ymxwoklght ltmysmbwkr (fzdbghpgec ) | - | 30 Jul 2022 | ||
(Participants with moderate renal impairment) | vvkihvwrky(zyntqfkabf) = visqofaxzr ltmysmbwkr (fzdbghpgec ) | ||||||
NCT02807909 (Pubmed) Manual | Phase 1 | - | 28 | eelajgcukn(olmjypsvdj) = jsslelsltj yakyicurqi (kjistrxfxl ) View more | Positive | 31 May 2022 | |
Phase 1/2 | 32 | (Treatment B) | ovkcnfstlx(xsmlhwfvgf) = xtnttoyfzx bylmujytju (ofxffebzyo, twcnwxdoth - xelzjllfho) View more | - | 29 Dec 2020 | ||
(Treatment C) | ovkcnfstlx(xsmlhwfvgf) = dcrsqskfgq bylmujytju (ofxffebzyo, meqxoxunry - daylrefpsw) View more | ||||||
Phase 2 | - | qkukjxupuw(bnghwrbzws) = xbbaooguvq zxfdqstjub (gwxizndbco ) | - | 12 Jul 2020 |