Last update 01 Nov 2024

MDNA-11

Overview

Basic Info

Drug Type
Cytokines
Synonyms
Target
Mechanism
IL-2R agonists(Interleukin-2 receptor agonists)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acral Lentiginous Malignant MelanomaPhase 2
KR
27 Aug 2021
Acral Lentiginous Malignant MelanomaPhase 2
AU
27 Aug 2021
Acral Lentiginous Malignant MelanomaPhase 2
US
27 Aug 2021
Acral Lentiginous Malignant MelanomaPhase 2
CA
27 Aug 2021
Gastrooesophageal junction cancerPhase 2
AU
27 Aug 2021
Gastrooesophageal junction cancerPhase 2
US
27 Aug 2021
Merkel Cell CarcinomaPhase 2
US
27 Aug 2021
Merkel Cell CarcinomaPhase 2
CA
27 Aug 2021
Merkel Cell CarcinomaPhase 2
AU
27 Aug 2021
Merkel Cell CarcinomaPhase 2
KR
27 Aug 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
14
(aumuuuecmt) = ufnjipylfy bnaxcjrllk (thlgnwpewm )
Positive
13 May 2024
Phase 1/2
30
(gcrwkzwdpp) = none umhtuaeraa (vixhyuyocz )
-
05 Apr 2024
Phase 1/2
20
(ngvtcbhkhu) = MDNA11 was generally well tolerated across cohorts, with the majority of adverse events (AEs) being grade 1 or 2, with no grade 4 or 5 AEs. kvcvvestid (kfcpganwjp )
Positive
09 Aug 2023
Phase 1/2
-
kogftdvarp(vfbupuwrbb) = dose dependent activation of various biomarkers on effector cells without concomitant stimulation of immune suppression iyfwgbocep (vqdhbajzpc )
Positive
01 Nov 2022
Phase 1/2
14
(kqleqkdlca) = jadlrvgqpc ygwpxmtapo (ugiieumybf )
Positive
28 Sep 2022
Phase 1/2
Neoplasms
Last line
14
(dose escalation)
(gtulhdwyzh) = goaphvrxer jothzdkres (kxgqocjoxg )
Positive
27 Jul 2022
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Approval

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Regulation

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