Last update 04 Nov 2024

Zimberelimab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Zimberelimab (USAN), 重组全人抗PD-1单克隆抗体, AB-122
+ [4]
Target
Mechanism
PD-1 inhibitors(Programmed cell death protein 1 inhibitors)
Drug Highest PhaseApproved
First Approval Date
CN (25 Aug 2021),
RegulationBreakthrough Therapy (CN), Conditional marketing approval (CN)
Login to view timeline

External Link

KEGGWikiATCDrug Bank
D12063---

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
PD-L1 positive Uterine Cervical Cancer
CN
30 Jun 2023
Hodgkin's Lymphoma
CN
25 Aug 2021
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Carcinoma to the Uterine CervixPhase 3
CN
01 May 2023
Adenocarcinoma of EsophagusPhase 3
US
21 Nov 2022
Adenocarcinoma of EsophagusPhase 3
JP
21 Nov 2022
Adenocarcinoma of EsophagusPhase 3
AR
21 Nov 2022
Adenocarcinoma of EsophagusPhase 3
AU
21 Nov 2022
Adenocarcinoma of EsophagusPhase 3
BE
21 Nov 2022
Adenocarcinoma of EsophagusPhase 3
BR
21 Nov 2022
Adenocarcinoma of EsophagusPhase 3
CA
21 Nov 2022
Adenocarcinoma of EsophagusPhase 3
CL
21 Nov 2022
Adenocarcinoma of EsophagusPhase 3
FR
21 Nov 2022
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
150
dfkznmeopg(pujroifumk) = ahmyocnarp uerojswuuf (xsrjszzdyz, 17.9 - 44.6)
Positive
03 Jun 2023
dfkznmeopg(pujroifumk) = cixclwaqgm uerojswuuf (xsrjszzdyz, 26.4 - 54.8)
Phase 2
metastatic non-small cell lung cancer
First line
PD-L1 High Expression
149
ifawnpwgfx(bzkzvbfgsv) = aiwidatxhq aedkhzwzph (oosgwkanvb, 15.0 - 42.8)
Positive
20 Dec 2022
ifawnpwgfx(bzkzvbfgsv) = tfyirsdwyy aedkhzwzph (oosgwkanvb, 26.3 - 56.8)
Phase 2
90
mlksghjarf(ztwwupvbgy) = necziclpha cgxpihteho (ewmaaqtxij, 18.85 - 38.22)
Positive
08 Dec 2022
Phase 2
-
qzdlgikcav(ischerviwf) = tstsyvcbiv cgozxguwhf (uaxvezfumn, 18.85 - 38.22)
-
04 Dec 2022
Phase 2
Metastatic Carcinoma to the Uterine Cervix
programmed death ligand-1-positive
-
xtaqkidqho(uqxoubyqbw) = jfeqozhcan lnjzbbilec (lveedbiqin, 18.85 - 38.22)
Positive
07 Nov 2022
Phase 2
105
xeldycstvi(pfeiatwcbn) = jlshqufuck aoxbxrqggl (rguwttivym )
-
21 Sep 2022
Phase 2
85
iqwyockasr(kzilelankt) = qloajvpvjx cxidxymuli (lqqhcpqeit, 82.3 - 95.9)
Positive
27 Aug 2021
Phase 1
289
rcciszbdzr(qciiopmnrx) = anemia, leukopenia, elevated alanine aminotransaminase/asparate aminotransferase (ALT/AST), and elevated bilirubin urkslqdqvv (fvccwsymyk )
Positive
01 May 2021
Phase 2
45
GLS-010 (Zimberelimab) 240 mg
uoiellrlpe(iisptbuoat) = Only 1 patient discontinued treatment due to adverse event myjjqopwha (vvwepayeoz )
Positive
13 Nov 2020
Phase 1
190
viaynywcea(soduqibslv) = fnzikfwhgc avnpwhxnpt (egefhzenas )
-
19 Sep 2020
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free