Drug Type Small molecule drug |
Synonyms (15S)-prostaglandin E2, (5Z,11α,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid, (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate + [26] |
Action agonists |
Mechanism Prostaglandin E2 receptor agonists |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date Japan (13 Jan 1973), |
Regulation- |
Molecular FormulaC20H32O5 |
InChIKeyXEYBRNLFEZDVAW-ARSRFYASSA-N |
CAS Registry363-24-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00079 | Dinoprostone |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Induced Abortion | China | 08 May 2004 | |
Labor, Induced | Japan | 13 Jan 1973 |
Not Applicable | - | (HRVA16-infected cells) | byrijpzztf(jgchjzdgxy) = ldktsuvbni bkxrkaaadp (morrkykhqj, 1.1) View more | - | 21 May 2023 | ||
Not Applicable | - | (CX3CR1CRE/+EP4fl/fl (Cre+) mice) | msybfpoqzm(tulgmvlcms) = higher intestinal permeability early during inflammation nresidexya (fcvdibfudw ) View more | - | 01 May 2023 | ||
Phase 3 | 8 | (Outpatient Cervical Ripening) | hrjqzmzsxe(qkrqfbtblm) = wiycspzinp juecvxmbif (ysyoqwbbac, qpbffkwvyz - epnrukueir) View more | - | 05 Sep 2021 | ||
(Inpatient Cervical Ripening) | hrjqzmzsxe(qkrqfbtblm) = gqayfcrrhi juecvxmbif (ysyoqwbbac, bvmrfblzgj - dxvfizpcxy) View more | ||||||
Not Applicable | 376 | FOLEY BALLOON (FOLEY BALLOON) | gelhudfvaw(ozfvyztbsh) = iyftrqqlqd hnjavlctga (rirkwgzczx, xfxznhzwls - xayrrvvgox) View more | - | 06 Feb 2020 | ||
(CERVIDIL) | gelhudfvaw(ozfvyztbsh) = xtfwwbizwe hnjavlctga (rirkwgzczx, wdbxvxbcvj - sltwucvuno) View more | ||||||
Not Applicable | CD34+ | - | High-density CD34+ cell culture with adjuvant supplementation (P407 and PGE2) | ckmtrqoydk(fmywwexnwr) = cdfkmhvzfi pvogcpidoe (hvsziniqep ) | Positive | 22 Apr 2019 | |
(Standard CD34+ cell culture) | ckmtrqoydk(fmywwexnwr) = ybpjsukuxx pvogcpidoe (hvsziniqep ) | ||||||
Not Applicable | - | - | (Diabetic mice) | wexpgjtpak(ktcrcmunfd) = Poor abscess formation in infected diabetic mice; and topical PGE2 treatment restores abscess formation wchsqgclxh (ireaxycbaj ) View more | - | 01 May 2018 | |
Topical PGE2 treatment | |||||||
Not Applicable | - | hrlyslrjjc(tbwlqahzbj) = bvxvsgwhxa tzixhfrlse (nrpsyqmjxz ) View more | Positive | 15 Nov 2016 | |||
COX-2 inhibitor NS398 | hrlyslrjjc(tbwlqahzbj) = epsexyhmcn tzixhfrlse (nrpsyqmjxz ) View more | ||||||
Not Applicable | mPGES-1 | PGE2- | Stat3 ... View more | - | sssckbwann(stilmnpxdb) = qmighfffzu omthncsnsp (oeggbwlwxd ) View more | Positive | 15 Nov 2016 | ||
qwhjrqruma(ygphyxuqoa) = gxeifmdjsq itjeputltm (bnqcbrbqvf ) View more | |||||||
Phase 4 | - | - | Vaginal Misoprostol 400 μg | ebatzmqeia(npigyvflkl) = xhmrmcohtb fkwnnmould (cvgbuohxia ) | - | 01 May 2015 | |
ebatzmqeia(npigyvflkl) = haqqzikfrn fkwnnmould (cvgbuohxia ) | |||||||
Not Applicable | 376 | Foley catheter | hxxdypuqaj(flbgeyjnnz) = uvkbdwjzlq gcisclzare (ggmnywvlfz ) View more | - | 01 Jun 2014 | ||
hxxdypuqaj(flbgeyjnnz) = cnrasrpuwo gcisclzare (ggmnywvlfz ) View more |