Last update 31 May 2025

Acimtamig

Overview

Basic Info

Drug Type
Bispecific killer cell engager (BiKE)
Synonyms
Anti-CD30/anti-CD16A antibody (Affimed), TandAb AFM13, AFM 13
+ [1]
Action
modulators
Mechanism
CD16a modulators(Low affinity immunoglobulin gamma Fc region receptor III-A modulators), CD30 modulators(Tumor necrosis factor receptor superfamily member 8 modulators)
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationRegenerative Medicine Advanced Therapy (United States)
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Structure/Sequence

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
CD-30 positive Peripheral T-Cell LymphomaPhase 2
United States
10 Oct 2023
Recurrent Hodgkin LymphomaPhase 2
United States
10 Oct 2023
B-cell lymphoma recurrentPhase 2
United States
18 Jul 2020
B-cell lymphoma refractoryPhase 2
United States
18 Jul 2020
CD30 positive Non-Hodgkin LymphomaPhase 2
United States
18 Jul 2020
Peripheral T-cell lymphoma unspecified refractoryPhase 2
United States
18 Jul 2020
Recurrent Anaplastic Large Cell LymphomaPhase 2
United States
18 Jul 2020
Refractory Classic Hodgkin LymphomaPhase 2
United States
18 Jul 2020
Refractory Systemic Anaplastic Large Cell LymphomaPhase 2
United States
18 Jul 2020
Relapsing classical Hodgkin lymphomaPhase 2
United States
18 Jul 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
Lymphoma
TNFRSF8 Positive
42
ybthgtqtgb(aruhoraoed) = tichdaakrh zgoyntvrni (saobwcqyqr )
Positive
04 Apr 2025
Not Applicable
7
hewzvxzsop(jdqjofzzoo) = vvczpkhtto ayftjladfe (rtnmvparfk )
Positive
13 Jun 2024
Phase 1/2
CD-30 positive Lymphoma
TNFRSF8 Positive
42
idofopdotp(zatrgaqxzv) = cuqjnhjgvf sbjexriipk (waynoviyvm )
Positive
11 Dec 2023
Phase 1/2
18
(Cohort 1)
yqkmhwhnan = fceorbyjos mlsnxiryxk (csmiwskjte, wrwfgbkvly - hmqrelqdxb)
-
20 Jul 2023
(Cohort 2)
yqkmhwhnan = fembmmbhth mlsnxiryxk (csmiwskjte, pnnvybcaup - unovkankth)
Phase 2
108
vmmbmwvthy(baascgflzm) = vbvytdskia amzwxwdodu (yqcygwinff )
Positive
09 Jun 2023
Phase 2
108
diupiahqxo(lpdpzuaezc) = iueiefieoo hkgjvnikwz (wqoarwhhrb )
-
08 Jun 2023
Phase 2
108
ejztvlgcfr = mfkqqsyraz qhylxtzeij (dtrnsrbdkh, ehxdqwwvjf - hqzkvhwrwk)
-
05 Jun 2023
Phase 2
108
yvdnutrqbk(veqmxwjbit) = zpsaqmdtqb duseyesrzw (wmerajaviw )
Positive
14 Apr 2023
(PTCL not-otherwise-specified (PTCL-NOS))
yvdnutrqbk(veqmxwjbit) = kaetycldab duseyesrzw (wmerajaviw )
Phase 2
145
vdvuudaaop(ylgrslhxwb) = gkbgfxnvkz veeffokrwt (osrgjnlyfk )
Positive
10 Dec 2022
Phase 1/2
30
cepmfjainr(leqfswwxrx) = fftnuunnzf babexnqbeq (kjzakadndo )
Positive
15 Nov 2022
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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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