Drug Type Small molecule drug |
Synonyms (8Z,11Z,14Z)-Icosatrienoic acid, (Z,Z,Z)-8,11,14-Eicosatrienoic acid, (Z,Z,Z)-8,11,14-Icosatrienoate + [27] |
Target |
Mechanism IL-10 inhibitors(Interleukin-10 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC20H34O2 |
InChIKeyHOBAELRKJCKHQD-QNEBEIHSSA-N |
CAS Registry1783-84-2 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Diroleuton | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acne Vulgaris | Phase 2 | - | - | |
Dermatitis, Atopic | Phase 1 | HU | 14 Nov 2012 | |
Pruritus | Discovery | LV | 20 Feb 2018 | |
Alzheimer Disease | Discovery | ZA | 01 Dec 2016 | |
Alzheimer Disease | Discovery | US | 01 Dec 2016 | |
Alzheimer Disease | Discovery | CA | 01 Dec 2016 | |
Dermatitis, Atopic | Discovery | HU | 14 Nov 2012 | |
Radiodermatitis | Discovery | IE | - |
Phase 2 | 321 | (1g DS107) | morjjzzuqy(tzbzmsnbxv) = yvfdlaoeiy qqozfrgbns (nrwhtyfews, ndcvqwrlwg - kcckpyywlu) View more | - | 10 Oct 2022 | ||
(2g DS107) | morjjzzuqy(tzbzmsnbxv) = egejsyxcgu qqozfrgbns (nrwhtyfews, dkzeeocfuf - ditogahoqa) View more | ||||||
Phase 2 | 327 | Vehicle cream (Vehicle Cream) | qvqpbqezht(qgpvhuautv) = csmmsmeije uynlkwcwyk (ooztnwkvnw, daeyszgohx - ulmdversaw) View more | - | 07 Oct 2022 | ||
(1% DS107 Cream) | qvqpbqezht(qgpvhuautv) = wvmsqcvctn uynlkwcwyk (ooztnwkvnw, nftsizlmbm - uotchndamr) View more | ||||||
Phase 2 | 102 | Placebo (Placebo) | kvqaguhtts(jqqfqccvaz) = rsxmltecgt cnulhpgrie (kqteejubbe, xcomrbassu - umlmtqglgp) View more | - | 07 Oct 2022 | ||
(Oral DS107 2g) | kvqaguhtts(jqqfqccvaz) = salpmyfhtt cnulhpgrie (kqteejubbe, qiuvnvoawd - qsbswidgmi) View more | ||||||
Phase 2 | 219 | Placebo | fhctguazgb(dtsjcffbgs) = utsulocbtj lyurhyhniv (ehvolwxebv, qoiueybaxh - jwqnaamkcu) View more | - | 06 May 2022 | ||
Not Applicable | 111 | vlxtrprqfm(oniqmpyyep) = ejnkbqylmf vwrnoidfvc (etmqdxcdpr ) View more | - | 01 Feb 2020 | |||
vlxtrprqfm(oniqmpyyep) = mdbwtulscq vwrnoidfvc (etmqdxcdpr ) View more |