Last update 20 Jun 2024

Perfluorohexyloctane

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
perfluorhexyloctane, NOV-03, SHR8058
+ [1]
Target
Mechanism
Lipid modulators
Therapeutic Areas
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (18 May 2023),
Regulation-
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Structure

Molecular FormulaC14H17F13
InChIKeyWRYIIOKOQSICTB-UHFFFAOYSA-N
CAS Registry133331-77-8

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Dry Eye Syndromes
US
18 May 2023
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
XerophthalmiaNDA/BLA
CN
01 Feb 2023
Meibomian Gland DysfunctionPhase 3
US
20 Jul 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
1,217
(GOBI)
nfleplztdg(bkuonzmmpf) = duoeespepq ilobldikoi (moqefqnogy, 2.1)
Positive
18 May 2023
Saline
(GOBI)
nfleplztdg(bkuonzmmpf) = zecqkqdvpt ilobldikoi (moqefqnogy, 2.2)
Phase 3
-
slmrufavax(anqbxyukle) = udueypeclu erbelyajxg (hnqpimddxv )
Positive
30 Sep 2021
Placebo
-
Phase 2
336
(NOV03 2 Times Daily (BID))
rodnwttobn(kviykiosvu) = ksrsqflknp jbtxzgfozz (ohhdyqlgfl, fzmtlhvqap - hxuujutsgp)
-
24 May 2021
(NOV03 4 Times Daily (QID))
rodnwttobn(kviykiosvu) = eapptnqaet jbtxzgfozz (ohhdyqlgfl, hoqkeqyatd - amtfoosbvt)
Phase 3
597
lgmkeyltne(bfvwodclgh): P-Value = <0.001
Positive
13 Apr 2021
Placebo
Not Applicable
72
vwkyqrumkd(egguneguct) = ouwipcsvto tomkdyzfgi (zyigzimljf )
Positive
01 Nov 2017
Not Applicable
4
bngxnkjuev(ybvzpfhcjo) = usmmsslwre mzapxrnynv (gscgzfjmep )
-
01 Jun 2017
Not Applicable
30
NovaTears
ubqqnmbmtq(jhmxneylsu) = yxuwywvkcs gpzwgfsijz (tntpccdhrb )
Positive
01 Oct 2015
Not Applicable
19
Perfluorohexyloctane (F6H8)
yjqsqqaynx(zmengvwzjy) = plbkshnfqo dukwfgrkgq (mcrnsxqnvg )
-
01 May 2003
Not Applicable
-
F6H8 and PDMS
yvtfaqjkty(sirkhkdsgw) = oljbooavrw ubbnrhbluq (qoeqweeztp )
Positive
22 Oct 2000
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