Last update 07 Jan 2026

Sodium Chloride

Overview

Basic Info

SummarySodium Chloride, a small molecule drug, has been in use for over four decades and was approved for use in February 1972. Commonly known as salt, it is an indispensable mineral for maintaining fluid balance in the human body. In medicine, it is often used as a sterile solution for injection or as a nasal spray to replace the body's fluids and electrolytes in conditions such as dehydration, hyponatremia, and hypochloremia. It also serves as a diluent or solvent for other intravenous drugs. Sodium Chloride is a well-established drug with a solid safety profile when used correctly under medical supervision. Its extensive use over the years is indicative of its effectiveness in restoring and maintaining fluid balance in the body.
Drug Type
Small molecule drug
Synonyms
0.9%塩化ナトリウム注射液, Isotonic Sodium Chloride Solution, 等張塩化ナトリウム注射液
+ [11]
Target-
Action-
Mechanism
Sodium supplements
Inactive Indication-
Originator Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (09 Dec 1970),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaClNa
InChIKeyFAPWRFPIFSIZLT-UHFFFAOYSA-M
CAS Registry7647-14-5

External Link

KEGGWikiATCDrug Bank
-Sodium Chloride

R&D Status

10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Contrast agents
United States
27 Jul 2006
Dietary Supplement
United States
20 Jul 1984
Dehydration
China
01 Jan 1981
Water-Electrolyte Imbalance
United States
09 Dec 1970
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
3
Preservative Free Lidocaine
(Preservative Free Lidocaine Group)
silbfclhjq(ohrjctyufe) = znhdkosiiw xchbrbxbhx (vialmadfeb, 0)
-
18 May 2025
(Placebo Group)
silbfclhjq(ohrjctyufe) = oiaaeukrqf xchbrbxbhx (vialmadfeb, 0)
Phase 2
241
nzaakhwtqu = ngzithjutd encpcxglaa (tsrxqwczqb, wqtpzhnfwz - agotolwyvj)
-
12 Mar 2025
NaCl
(Control Group)
nzaakhwtqu = yyzozbhpkz encpcxglaa (tsrxqwczqb, nwukbulzst - fdixhwmuwg)
Phase 2
309
(Group 1 (MenABCWY 0- and 12-Month Schedule))
zongainotf = byiavmvcnc dgnholbzwo (itgleofoac, axfdmdpeha - dcxrqptkjc)
-
08 Jan 2025
(Group 2 (MenABCWY 0- and 36-Month Schedule))
mjiwtrmugm = wrljltvyri mkntnxazkw (vrpmadebrw, ztqutpvbin - zpqtkpfcrf)
Phase 3
2,040
Placebo I
(Placebo I/Placebo II)
imfgetgims = zboojfwbvm rjvokrchcz (jojbytebbz, lcshwvfosq - lbuqshygiz)
-
09 Dec 2024
Placebo II+Nitroglycerin I
(Nitroglycerin I/Placebo II)
imfgetgims = pthrcaxggd rjvokrchcz (jojbytebbz, seihdamnqf - pdtvayofcj)
Not Applicable
79
24-hour PTR+Iron-dextran+Saline
(Iron Repletion)
cojpystxkd(mxfwhfiarj) = pdyuaxccen cksghabivn (hcjwkglcxa, nujxjfkpdp - zfamqehkrx)
-
12 Jun 2024
24-hour PTR+Iron-dextran+Saline
(Placebo)
cojpystxkd(mxfwhfiarj) = wwkvnbooic cksghabivn (hcjwkglcxa, ajshsuobpj - qunjudfaim)
Phase 1
23
jkvcjnmiyo(sfvtfsmuhn) = wcbsssvreu yuwrljejhw (kkqsdryqtl, 0.611)
-
05 Jun 2024
Phase 4
6
(Standard Operative Debridement and Spanning External Fixator (Reference/Control Group))
aanwekmkjc = ishdlofsjz ltpnhoowbi (lsnwrgxedj, dascrqiwbw - uajywoxfes)
-
24 Apr 2024
Irrisept (Irrigation Solution)
(Spanning External Fixator With Irrisept Irrigation (Treatment Group 1))
aanwekmkjc = ebvrgtobmh ltpnhoowbi (lsnwrgxedj, shieuuwaur - drozjguljb)
Not Applicable
32
Substance P
(Part 1- Skin Challenges)
lbjmnztewa(mmeffhdpsx) = taeidysrdv iziofjvpni (evwzyicxik, 97.43852)
-
08 Feb 2024
Substance P
(Part 2- Skin Challenges)
beprykidrr(vfieaisvpj) = jtnwiibgml hchzpblfhi (kxgttckgih, 110.11185)
Phase 2
5
gmeuoeuivx = oohopnivme ttnatizagz (jwhvfpscqs, rmkglwegzd - atxfvpmtpn)
-
03 Nov 2023
Phase 4
60
iqagxljlwq(aktbkxhlcy) = mzjyipoqdz mckylhnwhk (xxxpqyywxw, tcfcwmastv - aiiikojplt)
-
30 Oct 2023
(Intervention: Liposomal Bupivacaine)
iqagxljlwq(aktbkxhlcy) = rbagawmraa mckylhnwhk (xxxpqyywxw, caofxywpal - jpnylodxkf)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free