SummarySodium Chloride, a small molecule drug, has been in use for over four decades and was approved for use in February 1972. Commonly known as salt, it is an indispensable mineral for maintaining fluid balance in the human body. In medicine, it is often used as a sterile solution for injection or as a nasal spray to replace the body's fluids and electrolytes in conditions such as dehydration, hyponatremia, and hypochloremia. It also serves as a diluent or solvent for other intravenous drugs. Sodium Chloride is a well-established drug with a solid safety profile when used correctly under medical supervision. Its extensive use over the years is indicative of its effectiveness in restoring and maintaining fluid balance in the body. |
Drug Type Small molecule drug |
Synonyms 0.9%塩化ナトリウム注射液, Isotonic Sodium Chloride Solution, 等張塩化ナトリウム注射液 + [11] |
Target- |
Action- |
Mechanism Sodium supplements |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date United States (09 Dec 1970), |
Regulation- |
Molecular FormulaClNa |
InChIKeyFAPWRFPIFSIZLT-UHFFFAOYSA-M |
CAS Registry7647-14-5 |
| KEGG | Wiki | ATC | Drug Bank |
|---|---|---|---|
| - | Sodium Chloride |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Contrast agents | United States | 27 Jul 2006 | |
| Dietary Supplement | United States | 20 Jul 1984 | |
| Dehydration | China | 01 Jan 1981 | |
| Water-Electrolyte Imbalance | United States | 09 Dec 1970 |
Phase 4 | 3 | Preservative Free Lidocaine (Preservative Free Lidocaine Group) | silbfclhjq(ohrjctyufe) = znhdkosiiw xchbrbxbhx (vialmadfeb, 0) View more | - | 18 May 2025 | ||
(Placebo Group) | silbfclhjq(ohrjctyufe) = oiaaeukrqf xchbrbxbhx (vialmadfeb, 0) View more | ||||||
Phase 2 | 241 | (NS Group) | nzaakhwtqu = ngzithjutd encpcxglaa (tsrxqwczqb, wqtpzhnfwz - agotolwyvj) View more | - | 12 Mar 2025 | ||
NaCl (Control Group) | nzaakhwtqu = yyzozbhpkz encpcxglaa (tsrxqwczqb, nwukbulzst - fdixhwmuwg) View more | ||||||
Phase 2 | 309 | (Group 1 (MenABCWY 0- and 12-Month Schedule)) | zongainotf = byiavmvcnc dgnholbzwo (itgleofoac, axfdmdpeha - dcxrqptkjc) View more | - | 08 Jan 2025 | ||
placebo+MenABCWY vaccine (Group 2 (MenABCWY 0- and 36-Month Schedule)) | mjiwtrmugm = wrljltvyri mkntnxazkw (vrpmadebrw, ztqutpvbin - zpqtkpfcrf) View more | ||||||
Phase 3 | 2,040 | Placebo I (Placebo I/Placebo II) | imfgetgims = zboojfwbvm rjvokrchcz (jojbytebbz, lcshwvfosq - lbuqshygiz) View more | - | 09 Dec 2024 | ||
Placebo II+Nitroglycerin I (Nitroglycerin I/Placebo II) | imfgetgims = pthrcaxggd rjvokrchcz (jojbytebbz, seihdamnqf - pdtvayofcj) View more | ||||||
Not Applicable | 79 | (Iron Repletion) | cojpystxkd(mxfwhfiarj) = pdyuaxccen cksghabivn (hcjwkglcxa, nujxjfkpdp - zfamqehkrx) View more | - | 12 Jun 2024 | ||
(Placebo) | cojpystxkd(mxfwhfiarj) = wwkvnbooic cksghabivn (hcjwkglcxa, ajshsuobpj - qunjudfaim) View more | ||||||
Phase 1 | 23 | jkvcjnmiyo(sfvtfsmuhn) = wcbsssvreu yuwrljejhw (kkqsdryqtl, 0.611) View more | - | 05 Jun 2024 | |||
Phase 4 | 6 | (Standard Operative Debridement and Spanning External Fixator (Reference/Control Group)) | aanwekmkjc = ishdlofsjz ltpnhoowbi (lsnwrgxedj, dascrqiwbw - uajywoxfes) View more | - | 24 Apr 2024 | ||
Irrisept (Irrigation Solution) (Spanning External Fixator With Irrisept Irrigation (Treatment Group 1)) | aanwekmkjc = ebvrgtobmh ltpnhoowbi (lsnwrgxedj, shieuuwaur - drozjguljb) View more | ||||||
Not Applicable | 32 | Substance P (Part 1- Skin Challenges) | lbjmnztewa(mmeffhdpsx) = taeidysrdv iziofjvpni (evwzyicxik, 97.43852) View more | - | 08 Feb 2024 | ||
Substance P (Part 2- Skin Challenges) | beprykidrr(vfieaisvpj) = jtnwiibgml hchzpblfhi (kxgttckgih, 110.11185) View more | ||||||
Phase 2 | 5 | gmeuoeuivx = oohopnivme ttnatizagz (jwhvfpscqs, rmkglwegzd - atxfvpmtpn) View more | - | 03 Nov 2023 | |||
Phase 4 | 60 | (Control Arm) | iqagxljlwq(aktbkxhlcy) = mzjyipoqdz mckylhnwhk (xxxpqyywxw, tcfcwmastv - aiiikojplt) View more | - | 30 Oct 2023 | ||
(Intervention: Liposomal Bupivacaine) | iqagxljlwq(aktbkxhlcy) = rbagawmraa mckylhnwhk (xxxpqyywxw, caofxywpal - jpnylodxkf) View more |





