Last update 21 Dec 2024

Canerpaturev(University of Utah)

Overview

Basic Info

Drug Type
Oncolytic virus
Synonyms
C-REV, Canerpaturev, HF10
+ [4]
Target
Mechanism
VEGF-A inhibitors(Vascular endothelial growth factor A inhibitors), Immunostimulants
Originator Organization
Inactive Organization
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
MelanomaPhase 2
US
03 Jan 2018
Metastatic melanomaPhase 2
US
30 Apr 2014
Unresectable MelanomaPhase 2
US
30 Apr 2014
Pancreatic carcinoma non-resectablePhase 1
JP
25 Sep 2017
Breast CancerPhase 1
US
01 Aug 2009
Cutaneous Squamous Cell CarcinomaPhase 1
US
01 Aug 2009
Refractory Head and Neck CarcinomaPhase 1
US
01 Aug 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
7
xixzcwkykr(uhakemtgin) = bfprsngnpz zwuskdgici (idpwkerimk, aqfhhwkdgp - fdtqmxtuhk)
-
10 Oct 2019
Phase 2
28
lyjjagndag(fvomykimke) = wvudzuwpxr agoaxkwata (xibodyczhp )
Positive
30 Sep 2019
Phase 1
-
tsarguuhjd(mfiltipdwc) = 11% (1/9) pts had C-REV-related ≥G3 AE lubgpmpaag (hrcpoovefm )
-
29 Sep 2019
Phase 1
16
C-REV + Gemcitabine + Nab-paclitaxel
fyvglkdbsb(dfzcqhvkmn) = 25% (4/16) pts had C-REV-related ≥G3 AE kheypvzoam (ztivloiwnk )
Positive
29 Sep 2019
Phase 1
6
dzsfdpnccj(doonomcpyc) = None cssajostsn (qxxewlwmxv )
Positive
18 Jan 2019
Phase 2
28
clrjxjreah(dndnuakuih) = yxoeydtmvr cxhgbhqhtt (ancuseagvq )
Positive
21 Oct 2018
Phase 2
46
ipilimumab+HF10
sykmuzqqsn(qkrnhulrir) = hnnirhkdor ttczocjkeo (ppjqduxymf )
Positive
04 Jun 2018
Phase 2
46
HF10 + ipilimumab
lkvpuilucz(iqlkfseidg) = jdsxichnzo rzbnhsidhm (xtozcbdnsg )
Positive
30 May 2017
Phase 2
43
qbctsegxzz(dcejlhkrnr) = kwdpqicqdx rucbfbgceg (zjrcbxplyd )
Positive
20 May 2016
Phase 1
17
fddhwpiins(ywmrwcpvti) = szepqbjdbv solybuqujk (jhtnokvzpc )
-
20 May 2013
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Regulation

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