Last update 24 Mar 2025

Palifosfamide Tromethamine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ifosfamide mustard, Ifosforamide mustard, IPM-tris
+ [11]
Target-
Action-
Mechanism-
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseSuspendedPhase 3
First Approval Date-
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC8H22Cl2N3O5P
InChIKeyPGLRCMRTUIMSFQ-UHFFFAOYSA-N
CAS Registry1070409-31-2

External Link

KEGGWikiATCDrug Bank
D10373--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Extensive stage Small Cell Lung CancerPhase 3
United States
01 May 2012
Extensive stage Small Cell Lung CancerPhase 3
Australia
01 May 2012
Extensive stage Small Cell Lung CancerPhase 3
Canada
01 May 2012
Extensive stage Small Cell Lung CancerPhase 3
France
01 May 2012
Extensive stage Small Cell Lung CancerPhase 3
Hungary
01 May 2012
Extensive stage Small Cell Lung CancerPhase 3
Israel
01 May 2012
Extensive stage Small Cell Lung CancerPhase 3
Italy
01 May 2012
Extensive stage Small Cell Lung CancerPhase 3
Poland
01 May 2012
Extensive stage Small Cell Lung CancerPhase 3
Russia
01 May 2012
Extensive stage Small Cell Lung CancerPhase 3
Taiwan Province
01 May 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
188
fanaqtojwf(mqiaifyhdr) = fmmauofhwv lqokjwjcvm (gyhhmnelbl )
Negative
10 Aug 2017
fanaqtojwf(mqiaifyhdr) = oymahlxpgf lqokjwjcvm (gyhhmnelbl )
Phase 3
447
adypdtnukr(imrkmocyos) = wxsuedccnt xayqghfjvx (vvnvdcaroa )
Negative
10 Nov 2016
Doxorubicin+Placebo
adypdtnukr(imrkmocyos) = jhdtublhzs xayqghfjvx (vvnvdcaroa )
Phase 2
5
uvatrnmdye = qjxvpqapff fapyictcox (rsgterpdvb, idoilahfnz - irszxhbmrh)
-
02 Jul 2015
Phase 3
188
qrjpbanyhr(vuoynactsu) = thjmfakklz plziyothcj (iyqmsqihwf )
Negative
20 May 2015
qrjpbanyhr(vuoynactsu) = bkhppoabba plziyothcj (iyqmsqihwf )
Phase 2
Sarcoma
Second line
-
uujqzmmhov(ewbcqxkicr) = juoxkdgwyg uudahejhig (qgqkcjripq )
Positive
20 May 2010
uujqzmmhov(ewbcqxkicr) = cecrpntmll uudahejhig (qgqkcjripq )
Phase 1
13
ftdinzishc(pgrezsmmpm) = ihbjeostts fmwsctkqab (tqgeenhpkt )
-
20 May 2009
Phase 1
18
lpguvpdjmf(vryfxbnehs) = wzjpfdygot kklpdknaot (cktkutzltc )
-
20 Jun 2006
Phase 1
-
Isophosphoramide mustard-lysine (IPM-L; ZIO-201)
ctoysixbqv(zuzejjcgcg) = ubqnccxgop clqnktthza (jtmjyyaqiy )
-
01 Feb 2006
Cyclophosphamide (CPA)
dahogatrij(sksghamrsd) = janmqoorzi ajgrurqvmp (lgsedkplcp )
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Regulation

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