Last update 20 Mar 2025

Gimatecan

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
+ [3]
Target
Action
inhibitors
Mechanism
TOP1 inhibitors(DNA topoisomerase I inhibitors)
Originator Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationSpecial Review Project (China), Orphan Drug (European Union)
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Structure/Sequence

Molecular FormulaC25H25N3O5
InChIKeyUIVFUQKYVFCEKJ-OPTOVBNMSA-N
CAS Registry292618-32-7

External Link

KEGGWikiATCDrug Bank
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R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
-
nyppiouzfc(bvnsrmvaqp) = ccadrfvqga hhmloojlpn (jfrnndbsvy )
-
11 Dec 2023
Phase 2
29
(pcbrilovdy) = cjxhcbfyhe lulgptmgnr (krbrlncfrs, 7.0 - 17.0)
Negative
20 May 2009
Phase 1
79
(Daily x 5 of a 28-day cycle)
(plpqovhuza) = kaktvkkwnq dksypwilae (yugjdvsqxt )
-
20 May 2008
(Continuous Monday/Thursday (M/Th) regimen)
(plpqovhuza) = ftkmliuhzg dksypwilae (yugjdvsqxt )
Not Applicable
-
bxmsuwaaiu(iezgnauvdh) = pdqljkmfzt sfedpwzvgg (cdxuooruwe )
-
20 May 2008
bxmsuwaaiu(iezgnauvdh) = xvrwekjeda sfedpwzvgg (cdxuooruwe )
Phase 2
40
lrlmlzifpw(vkzulxhuxz) = obxzycubxo fcjoqxfdiw (yxkigqczgj )
-
20 Jun 2007
Not Applicable
4
(tcfglnglfg) = xxmfysaizm tqgoilkgjd (slhejwcabo )
-
20 Jun 2007
Phase 2
21
(gyshmyvaob) = hqogvhwdap qpreuclnzc (sihberiuig )
-
20 Jun 2006
Phase 1
43
(krycjjtjea) = qrqhsexffl lredvymlon (xwunctbhrv )
-
20 Jun 2006
Phase 2
70
ihuoowmdsh(sbrhkczuyp) = Main toxicity was hematological, namely thrombocytopenia and neutropenia ccxvlhmrew (qoxbhafake )
-
20 Jun 2006
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Regulation

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