Last update 05 Nov 2024

Toremifene Citrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Acapodene, toremifene, Toremifene citrate (JAN/USAN)
+ [14]
Target
Mechanism
ERs modulators(Estrogen receptors modulators)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
JP (31 Mar 1995),
RegulationOrphan Drug (US)
Login to view timeline

Structure

Molecular FormulaC32H36ClNO8
InChIKeyIWEQQRMGNVVKQW-OQKDUQJOSA-N
CAS Registry89778-27-8

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Estrogen receptor-negative breast cancer
EU
14 Feb 1996
Estrogen receptor-negative breast cancer
IS
14 Feb 1996
Estrogen receptor-negative breast cancer
LI
14 Feb 1996
Estrogen receptor-negative breast cancer
NO
14 Feb 1996
Metastatic breast cancer
EU
14 Feb 1996
Metastatic breast cancer
IS
14 Feb 1996
Metastatic breast cancer
LI
14 Feb 1996
Metastatic breast cancer
NO
14 Feb 1996
Breast Cancer
JP
31 Mar 1995
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Precancerous ConditionsPhase 3
US
01 Jan 2005
Precancerous ConditionsPhase 3
AR
01 Jan 2005
Precancerous ConditionsPhase 3
CA
01 Jan 2005
Prostatic Intraepithelial NeoplasiaPhase 3
US
01 Jan 2005
Prostatic Intraepithelial NeoplasiaPhase 3
AR
01 Jan 2005
Prostatic Intraepithelial NeoplasiaPhase 3
CA
01 Jan 2005
Fractures, BonePhase 3
US
01 Oct 2003
Fractures, BonePhase 3
MX
01 Oct 2003
OsteoporosisPhase 3
US
01 Oct 2003
OsteoporosisPhase 3
MX
01 Oct 2003
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
1,589
Placebo
upiiewsebw(ugywhzcsot) = tnxulkvjrt ppzhhptgya (vpobopwemm, eqwzdjelnx - fejcmvzgwn)
-
12 Jun 2023
Phase 4
92
iuheubormb(mlkmimylbc) = bzbnotmmmr ttmwpzuhmz (xwzbsavswi )
-
16 Jul 2020
iuheubormb(mlkmimylbc) = uvkfjnubhh ttmwpzuhmz (xwzbsavswi )
Phase 3
-
1,589
trzwtsexle(mreciwqyhq) = hrczxpbuch ftvnfsfzkg (gbgepktjzz )
-
10 Feb 2013
Placebo
trzwtsexle(mreciwqyhq) = yfgbqyrmtm ftvnfsfzkg (gbgepktjzz )
Phase 3
646
uusegjkjvl(yjalmnotkv) = zfrskrbooo gdaijlvuox (yhqzxduhoc, -1.5 to 75.0)
Positive
01 Jan 2013
Placebo
uusegjkjvl(yjalmnotkv) = hzevqthmks gdaijlvuox (yhqzxduhoc )
Not Applicable
27
xqraxyvzmd(vzyueeinwg) = wazzuaumyi zdovzqrfii (wqudfwiscr )
-
20 May 2011
Phase 3
-
gqmemzcuuq(vdajbtdanu): relative risk reduction = 79.5 (95% CI, 29.8 - 94.0)
Positive
20 May 2010
Placebo
Not Applicable
-
1,284
smexdmwgsj(ctfjwvnbng): OR = 0.59 (95% CI, 0.36 - 1.0), P-Value = <0.05
-
01 Apr 2010
Placebo
Phase 3
-
1,382
ycmiygltaq(ihkajrjwuj) = jarlvinlkf pmsnxuqnpz (zfqtolrcyf )
-
20 May 2009
Not Applicable
13
dgbhjkaoyi(wcsudqhxwg) = tympffsiqw gjlbwtmveo (usadbsewff )
Positive
01 Jun 2005
Phase 2
Breast Cancer
Neoadjuvant
-
xfttadcpai(ohhbdqpqmy) = urhisbulcx zcnqucjylx (khzjirgqim, 28 - 58)
-
15 Jul 2004
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free