Drug Type Small molecule-drug conjugates |
Synonyms Folate-TRPV6-peptide exatecan drug conjugate (Coherent), CBP 1019, CBP1019 |
Target |
Mechanism FOLR1 antagonists(Folate receptor alpha antagonists), TOP1 inhibitors(DNA topoisomerase I inhibitors), TRPV6 antagonists(Transient receptor potential cation channel subfamily V member antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
RegulationOrphan Drug (US) |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Advanced Malignant Solid Neoplasm | Phase 2 | US | 14 Mar 2023 | |
Advanced Malignant Solid Neoplasm | Phase 2 | CN | 14 Mar 2023 | |
Breast Cancer | Phase 2 | US | 14 Mar 2023 | |
Breast Cancer | Phase 2 | CN | 14 Mar 2023 | |
Colorectal Cancer | Phase 2 | US | 14 Mar 2023 | |
Colorectal Cancer | Phase 2 | CN | 14 Mar 2023 | |
Esophageal Carcinoma | Phase 2 | US | 14 Mar 2023 | |
Esophageal Carcinoma | Phase 2 | CN | 14 Mar 2023 | |
Lung Cancer | Phase 2 | US | 14 Mar 2023 | |
Lung Cancer | Phase 2 | CN | 14 Mar 2023 |