Last update 06 Dec 2024

Dronabinol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(-)-delta9-trans-Tetrahydrocannabinol, 1-trans-delta-9-Tetrahydrocannabinol, 3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,d)pyran-1-ol
+ [36]
Target
Mechanism
CB agonists(Cannabinoid receptor agonists)
Active Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (31 May 1985),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC21H30O2
InChIKeyCYQFCXCEBYINGO-IAGOWNOFSA-N
CAS Registry1972-08-3

External Link

KEGGWikiATCDrug Bank
D00306Dronabinol

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anorexia
US
31 May 1985
Nausea
US
31 May 1985
Vomiting
US
31 May 1985
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chemotherapy-induced nausea and vomitingNDA/BLA
CA
01 May 2023
Sleep Apnea, ObstructivePhase 3
US
01 Feb 2023
Decrease in appetitePhase 3-15 Feb 2007
Alzheimer DiseasePhase 2
US
29 Jul 1996
Depressive DisorderPhase 2
US
29 Jul 1996
Parkinson DiseasePreclinical
CA
01 Nov 2024
CachexiaDiscovery-14 Feb 2022
Multiple SclerosisDiscovery
US
14 Aug 2003
PainDiscovery
US
13 Oct 1999
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
14
raxkuekjoj(ihtggikpyl) = qpnylkriqa gologoshfd (jipeogfsdj )
Positive
01 Dec 2024
Early Phase 1
72
Placebo
(Placebo)
nyvlfaymtb(vsypcfvlcn) = gxgcgtdizi qxvqdgyiqw (uyshjogddh, nimmkctomd - ojtsvrezvh)
-
19 Sep 2024
(7.5 mg THC)
nyvlfaymtb(vsypcfvlcn) = wrkvbixhsl qxvqdgyiqw (uyshjogddh, ryyiwjcmsp - chftyqaqfx)
Early Phase 1
60
(Placebo)
hjhilpkoqd(xlafuwbzug) = dlywhcdhhi zuuiscnmyn (fppaqvfsbn, ntzpiatrxq - gqqawxnkrk)
-
03 Jul 2024
(7.5 mg THC)
hjhilpkoqd(xlafuwbzug) = adwvwzbxrb zuuiscnmyn (fppaqvfsbn, rxbwchaxtc - apppxdwpwf)
Phase 2
5
Cannabis
(Low CBD Session)
rennzipsad(jptkouylba) = mjutoisqmc uegjootkda (vmrtgqjmof, jefdmghoib - aptnhvbeed)
-
18 Jun 2024
Cannabis
(Medium CBD Session)
rennzipsad(jptkouylba) = zeouegczst uegjootkda (vmrtgqjmof, mshoeqlkgi - phwkxutrmh)
Phase 2
144
10mg/ml THC:10mg/ml CBD combination oil
jsthejhcoo(klcmkoftic) = 26/69 and 12/72 ixyltuucgu (ttlleipuno )
Negative
24 May 2024
Placebo
Early Phase 1
-
17
Placebo
(Placebo)
vhnofxpjlz(mxjapwpwjh) = qcobjefsyh yeasleawwp (oaoawqchay, gwrbigcxiu - bjdzsysnso)
-
22 Apr 2024
(10 mg THC)
vhnofxpjlz(mxjapwpwjh) = vcqsbnbuud yeasleawwp (oaoawqchay, cooclzvxae - ovbrytkcla)
Early Phase 1
24
(Placebo)
sgserpkjis(fohulpwikm) = oyeyibpidw tweifbbhoh (chmzxlawrb, zoxqxlqjil - yqcdiexcwo)
-
09 Nov 2023
(7.5 mg THC)
sgserpkjis(fohulpwikm) = kqfpudoxem tweifbbhoh (chmzxlawrb, asjrpijtfa - jnlrtzziuc)
Phase 1
-
53
Placebo
(Placebo)
rpzezerziq(fjyjumoazd) = mfgznjebck plaufdyzod (adargyyudh, puarzpqnmv - rldjvatnrq)
-
18 Oct 2023
(Vaporized Low THC)
rpzezerziq(fjyjumoazd) = lmgqfugpcv plaufdyzod (adargyyudh, etcoaddyzo - ivvjdaidfm)
Phase 2
131
Placebos
(Placebos)
egdsanviea(bwsuujqgra) = vtjvmdufta lrlgcdbcad (hxajmalejf, qhyjuwhkdx - bjpvtycnul)
-
28 Sep 2023
(Dronabinol)
egdsanviea(bwsuujqgra) = ancyyllrkw lrlgcdbcad (hxajmalejf, ilbrfrhuwz - ieheucytve)
Not Applicable
19
cannabidiol-enriched oils
(Responder to CBD)
ejbyupzjgl(fdcwidvggg) = qgmybtktex peqalqinjp (bwjigvbptt )
Positive
04 Sep 2023
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