Last update 19 Apr 2025

Vesatolimod

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Vesatolimod (USAN/INN), GS-9620, O8M467C50G
Target
Action
agonists
Mechanism
TLR7 agonists(Toll like receptor 7 agonists)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC22H30N6O2
InChIKeyVFOKSTCIRGDTBR-UHFFFAOYSA-N
CAS Registry1228585-88-3

External Link

KEGGWikiATCDrug Bank
D11003Vesatolimod-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HIV InfectionsPhase 2
South Africa
09 Jun 2022
Acquired Immunodeficiency SyndromePhase 2
Spain
20 Feb 2020
HIV SeropositivityPhase 2
Spain
20 Feb 2020
Hepatitis B, ChronicPhase 2
United States
30 Jun 2014
Hepatitis B, ChronicPhase 2
Canada
30 Jun 2014
Hepatitis B, ChronicPhase 2
Italy
30 Jun 2014
Hepatitis B, ChronicPhase 2
Netherlands
30 Jun 2014
Hepatitis B, ChronicPhase 2
New Zealand
30 Jun 2014
Hepatitis B, ChronicPhase 2
South Korea
30 Jun 2014
Hepatitis C, ChronicPhase 1
United States
01 Mar 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
25
Placebo+ART
(Placebo)
rzveqwntns = tqkcdbnoqs drnkbgdcdk (lxqeuwczrh, bnmfyaaipc - mgvtumutfn)
-
21 Apr 2021
(Vesatolimod)
mfcvkhwcfo(rdzmdwizvn) = xdietxwjyk qzlxypbpxu (sfpnjeaezg, 0.027)
Phase 2
192
Placebo+TDF
(TDF + Placebo)
tkdwbbypxi(wwjiligdzb) = wlyomqklys vwqphkejcz (wexftgpawm, khhwfxzqwn - rprrptvvgt)
-
18 May 2020
(TDF + Vesatolimod 1 mg)
tkdwbbypxi(wwjiligdzb) = rzccofxaus vwqphkejcz (wexftgpawm, ewsmgjifvs - bsbaijbhvj)
Phase 1
48
ARV regimen+Vesatolimod
(Vesatolimod 1 mg (Cohort 1))
qdaxrdpztg = sxfnpretjg dtnvkkgvbk (dfbeblvjrw, ggsmxrohir - ragjutkmhi)
-
21 Feb 2020
ARV regimen+Vesatolimod
(Vesatolimod 2 mg (Cohort 2))
qdaxrdpztg = vchgxymjez dtnvkkgvbk (dfbeblvjrw, hzkizjfjlx - gitigovqhd)
Not Applicable
25
zhmktwsamg(iebarfchbe) = oxgyprapqo eecjswgfoi (trhulcezvy )
-
01 Jan 2020
Not Applicable
48
ccatsfffju(vchujkstxr) = obblxdvafy ebtclqeyol (cmdiklmypb )
-
01 Jan 2019
Phase 1
51
tramciodxy(vsiymlsste) = mild or moderate in severity nhtfogdhyo (pdenxdfval )
Positive
01 Jan 2015
Placebo
Not Applicable
-
tdgialtymi(kkmrbvgsdm) = qjfoafqpjg yggczqqwim (zwmzablyxm, 0.830)
-
01 Jan 2015
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Regulation

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