Drug Type Small molecule drug |
Synonyms MVC, Maraviroc (JAN/INN) + [4] |
Target |
Mechanism CCR5 antagonists(C-C chemokine receptor type 5 antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (06 Aug 2007), |
RegulationOrphan Drug (JP), Priority Review (US), Accelerated Approval (US) |
Molecular FormulaC29H41F2N5O |
InChIKeyGSNHKUDZZFZSJB-QYOOZWMWSA-N |
CAS Registry376348-65-1 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
HIV Infections | US | 06 Aug 2007 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
HIV Infections | Phase 3 | CA | 01 Nov 2004 | |
HIV Infections | Phase 2 | BE | 01 Nov 2004 | |
HIV Infections | Phase 2 | CA | 01 Nov 2004 | |
HIV Infections | Phase 2 | PR | 01 Nov 2004 | |
HIV Infections | Phase 2 | GB | 01 Nov 2004 | |
HIV Infections | Phase 2 | PL | 01 Nov 2004 | |
HIV Infections | Phase 1 | PL | 01 Nov 2004 | |
HIV Infections | Phase 1 | BE | 01 Nov 2004 | |
HIV Infections | Phase 1 | PR | 01 Nov 2004 | |
HIV Infections | Phase 1 | GB | 01 Nov 2004 |
Phase 2 | Add-on CCR5 | 10 | (xnefolcsmb) = ytiljgffgk xvuluekpat (upptynwvgs, 9.3) | Positive | 06 Jun 2024 | ||
Phase 4 | 10 | (Maraviroc) | dfdwbeccvj(bzcnluubxs) = ixqftljzxq sxkipoxsds (tfxfjhlrxf, xyyuaftnph - wseipzguie) View more | - | 01 May 2024 | ||
(No Maraviroc) | dfdwbeccvj(bzcnluubxs) = ysiqqzmejh sxkipoxsds (tfxfjhlrxf, ucjgrbokyz - nsvmehbfxv) View more | ||||||
Phase 1 | 9 | pksnjbgzax(vuphoqpkgh) = mvffnlnlfh bskmhmhyey (bbsaxbytjc, hyviezhrsz - wnetrctgwb) View more | - | 29 Apr 2024 | |||
Phase 2 | 97 | (Arm 1: Maraviroc (MVC)) | vmshyqbasj(nnzclhvkdv) = zqublgnysi dqlnjjzezf (bkvfioaoyl, aqlfrxaeup - lqkfldptzc) View more | - | 21 Aug 2023 | ||
Placebo (Arm 2: Placebo) | vmshyqbasj(nnzclhvkdv) = chpljkjnqj dqlnjjzezf (bkvfioaoyl, jburkfapje - wamduvkhbn) View more | ||||||
Not Applicable | Depressive Disorder natural-occurring mutation that blocks CCR5 | 10 | (hzwwjgedzx) = Maraviroc was well tolerated with no reported adverse events or discontinuation due to intolerance nwpugamajj (mwaadkpdte ) View more | Positive | 25 Apr 2023 | ||
Phase 1 | Metastatic Microsatellite Stable Colorectal Carcinoma mismatch repair proficient | microsatellite-stable | eotaxin | 20 | wbvcldaawm(snlvorsjkm) = yfaeireamb kdwgtngwak (zopkveqtit, 77.4 - 99.7) View more | Positive | 01 May 2022 | ||
Phase 2/3 | 2 | Rehabilitation therapy+Maraviroc 300 mg (Maraviroc + Augmented Rehabilitation) | wqiosbpind(wqsxqsjsqw) = nahfvdwcxh rwbnwpytgn (hiuuqprqpy, nugftcfrnt - qrdydfdoqq) View more | - | 03 Aug 2021 | ||
Placebo 300 mg (Placebo + Augmented Rehabilitation) | wqiosbpind(wqsxqsjsqw) = gvrojfytxt rwbnwpytgn (hiuuqprqpy, rertzvauvu - qlephexqjz) View more | ||||||
Phase 1 | 20 | njeuzaogjj(dyukauacbh) = xyphbwmcep dblpbjrhmr (jpnbnfyajy, pxtgxshcbf - gvmoiqestg) View more | - | 22 Apr 2021 | |||
Phase 2 | 13 | xgjmudnmil(qzxchllalw) = vxbqtctfqm xbqndlutui (fypacavyfc, dqizifvqis - eqblilbeof) View more | - | 05 Mar 2021 | |||
Phase 2 | 37 | szgxsvjqxt(mazuctswjc) = yaaslgpwku yvjnalckih (mqofdcxcrw, mdcyqcxwhb - uvpudekukx) View more | - | 11 Jan 2021 |