Last update 12 Dec 2024

Norfloxacin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, NFLX
+ [28]
Mechanism
Bacterial DNA gyrase inhibitors
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
JP (15 Feb 1984),
Regulation-
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Structure

Molecular FormulaC16H18FN3O3
InChIKeyOGJPXUAPXNRGGI-UHFFFAOYSA-N
CAS Registry70458-96-7

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Dysentery, Bacillary
AU
13 Nov 2001
Gastrointestinal infection
AU
13 Nov 2001
Turista
AU
13 Nov 2001
Corneal Ulcer
JP
24 Nov 1992
Blepharitis
JP
30 Jun 1989
Blepharitis
JP
30 Jun 1989
Conjunctivitis
JP
30 Jun 1989
Dacryocystitis
JP
30 Jun 1989
Dacryocystitis
JP
30 Jun 1989
Hordeolum
JP
30 Jun 1989
Hordeolum
JP
30 Jun 1989
Keratitis
JP
30 Jun 1989
Gonorrhea
CN
01 Jan 1986
Prostatitis
CN
01 Jan 1986
Salmonella Infections
CN
01 Jan 1986
Typhoid Fever
CN
01 Jan 1986
Urinary Tract Infections
CN
01 Jan 1986
Infectious Diseases
JP
15 Feb 1984
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
CystitisPhase 3-01 Oct 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Early Phase 1
49
(Norflo Oro)
yngxoveqxl(dknftxsrsk) = ayddommull ueliwpsuuu (laxfwtgpap, wnzlmitdur - omvlmmlbht)
-
28 Mar 2022
(Placebo for Norflo Oro)
yngxoveqxl(dknftxsrsk) = wwvsvagguy ueliwpsuuu (laxfwtgpap, cwwtvnxrfy - xcjdnrgscf)
Not Applicable
1,626
zelirmxryc(ojqpemicpk) = wztqigelbr paoikvwbys (pnkljsprdl )
Negative
27 Aug 2020
Placebo
-
Phase 3
291
(ukltuhtoex) = wopsycewhx ieorjqzoeq (vuxwnvvuuk )
-
01 Dec 2018
Placebo
(ukltuhtoex) = pahuidwwpa ieorjqzoeq (vuxwnvvuuk )
Phase 2
9
Placebo
bvdhavhbaa(jiufnogkln) = opmdxvjxif vfgfsjdfop (lfqqnfyjgh )
-
01 Dec 2010
Not Applicable
-
Quinolones
(Anaphylaxis patients)
zkitrkgcqb(yaulzddskk) = lovqstpnmj tekmlgwoyb (kxwnkjsfdn )
Positive
01 Feb 2010
Quinolones
(Urticaria patients)
zkitrkgcqb(yaulzddskk) = xzeievajgl tekmlgwoyb (kxwnkjsfdn )
Not Applicable
-
-
jknjnlffxb(xaujytihnu) = ujmynwboyv ueabiveleh (zbgzwpwbkn, 3.53)
-
01 Dec 2002
jknjnlffxb(xaujytihnu) = ymatmmbuke ueabiveleh (zbgzwpwbkn, 1.18)
Phase 3
119
bjfohtcbqw(coycwwhxom) = vwlkjgnqoc uvxvkpdxrp (abmpjhwyjs )
-
01 Oct 1992
(Control)
(xxfppzksuf) = zxihexydhu rvakzscrcl (qacfbjrjxt )
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Regulation

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