Last update 11 Nov 2024

ASN-007

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ASN 007A, ASN-0007, ERAS 007
+ [1]
Mechanism
ERK1 inhibitors(Extracellular-signal-regulated kinase1 inhibitors), ERK2 inhibitors(Extracellular-signal-regulated kinase 2 inhibitors)
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Colorectal CarcinomaPhase 2
US
20 Sep 2021
Metastatic Pancreatic Ductal AdenocarcinomaPhase 2
US
20 Sep 2021
Advanced Malignant Solid NeoplasmPhase 2
US
07 May 2021
Metastatic Solid TumorPhase 2
US
07 May 2021
Gastrointestinal NeoplasmsPhase 2
US
-
BRAF V600E mutant Colorectal CancerPhase 1
US
20 Sep 2021
colon cancer liver metastasisPhase 1
US
19 Jan 2018
Metastatic colon cancerPhase 1
US
19 Jan 2018
Metastatic melanomaPhase 1
US
19 Jan 2018
metastatic non-small cell lung cancerPhase 1
US
19 Jan 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
19
ueajhdanba(ytyruidjui) = 26.3% kvexepmnxy (ezqheamacg )
Positive
24 May 2024
Phase 1/2
12
lnwkobabtd(wdsgycpkwd) = yxzljzvlwu opetbuqjfj (eteurvtpbl )
Positive
31 May 2023
Phase 1/2
30
fsneksamwq(gfcyjvgfiy) = kwnszdnhpg tykebwnxir (altrwvavex )
Positive
26 May 2023
Phase 1/2
-
nqxidvdtht(ypbrjwhocw) = Monitorable and manageable adverse event (AE) profile with mostly grade 1 and 2 treatment-related AEs obpqsaspmo (tifwlsfsrq )
Positive
12 Oct 2022
Phase 1
RAS/RAF mutation Solid Tumors
RAS Mutation | RAF Mutation | MEK Mutation
-
cieogqqpca(ymwutiqkbv) = 40mg QD and 250mg QW,respectively ergsblomix (oqbkwmjpas )
Positive
01 Dec 2019
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Regulation

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