Drug Type Small molecule drug |
Synonyms 5-aminolevulinic acid methyl ester, Aminolevulinic acid methyl ester, methyl 5-aminolevulinate + [14] |
Target- |
Action- |
Mechanism Photosensitizers |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date United Kingdom (27 Nov 2001), |
RegulationOrphan Drug (South Korea) |
Molecular FormulaC6H12ClNO3 |
InChIKeyUJYSYPVQHFNBML-UHFFFAOYSA-N |
CAS Registry79416-27-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D04988 | Methyl Aminolevulinate Hydrochloride |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Keratosis | South Korea | 27 Oct 2006 | |
Basal Cell Carcinoma | Australia | 04 Apr 2003 | |
Actinic Keratosis | Austria | 27 Nov 2001 | |
Actinic Keratosis | Belgium | 27 Nov 2001 | |
Actinic Keratosis | Denmark | 27 Nov 2001 | |
Actinic Keratosis | Finland | 27 Nov 2001 | |
Actinic Keratosis | Germany | 27 Nov 2001 | |
Actinic Keratosis | Greece | 27 Nov 2001 | |
Actinic Keratosis | Iceland | 27 Nov 2001 | |
Actinic Keratosis | Ireland | 27 Nov 2001 | |
Actinic Keratosis | Italy | 27 Nov 2001 | |
Actinic Keratosis | Luxembourg | 27 Nov 2001 | |
Actinic Keratosis | Netherlands | 27 Nov 2001 | |
Actinic Keratosis | Norway | 27 Nov 2001 | |
Actinic Keratosis | Portugal | 27 Nov 2001 | |
Actinic Keratosis | Slovakia | 27 Nov 2001 | |
Actinic Keratosis | Sweden | 27 Nov 2001 | |
Actinic Keratosis | United Kingdom | 27 Nov 2001 | |
Bowen's Disease | Austria | 27 Nov 2001 | |
Bowen's Disease | Belgium | 27 Nov 2001 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Facial Dermatoses | Phase 3 | Colombia | 01 Feb 2008 | |
Skin aging | Phase 3 | Colombia | 01 Feb 2008 | |
Metastatic basal cell carcinoma | Phase 3 | Australia | 01 Oct 2000 | |
Superficial basal cell carcinoma | Phase 3 | Austria | 18 Oct 1999 | |
Superficial basal cell carcinoma | Phase 3 | Belgium | 18 Oct 1999 | |
Superficial basal cell carcinoma | Phase 3 | Finland | 18 Oct 1999 | |
Superficial basal cell carcinoma | Phase 3 | France | 18 Oct 1999 | |
Superficial basal cell carcinoma | Phase 3 | Italy | 18 Oct 1999 | |
Superficial basal cell carcinoma | Phase 3 | Sweden | 18 Oct 1999 | |
Superficial basal cell carcinoma | Phase 3 | United Kingdom | 18 Oct 1999 |
Not Applicable | 224 | zgohigujps(lnjmskstdk) = hxrkfvqqot qvdtzuvicl (rbwlrkbpik ) View more | Positive | 07 Nov 2024 | |||
Phase 3 | 120 | (Metvix® PDT) | tgsttyqfeo = nirsxlouga cresjeauow (owmcwlwyxw, dpsebkitwu - yplofohdwi) View more | - | 19 Aug 2024 | ||
Hand held liquid nitrogen spray cryotherapy (Cryotherapy) | tgsttyqfeo = vysoedhtpy cresjeauow (owmcwlwyxw, dfwudkwmvu - kgfxcesrlb) View more | ||||||
Phase 3 | 66 | (Metvix® Cream 160 Milligram Per Gram) | kfqcmojdde = aovfueytbl ricsyfkddc (najfutioes, rohgoiiedo - txshilrxrr) View more | - | 06 Aug 2024 | ||
Placebo (Placebo) | kfqcmojdde = mmcjoiniwt ricsyfkddc (najfutioes, aqgbheorzb - kznwtfdxbr) View more | ||||||
Phase 3 | 65 | Photodynamic Therapy (PDT)+Metvix cream | yvjuaxqliu = fsocjakpnh ccgozedtsz (ysmtkznfrg, uceszakmbh - urkmyopaht) View more | - | 05 Aug 2024 | ||
Phase 3 | 125 | (MAL Cream Arm) | lghwyiupmv = xlmmyqynli ncckqgufud (refcacosom, umamfvmhuq - zydwipldyq) View more | - | 10 Oct 2023 | ||
Vehicle cream (Vehicle Cream Arm) | lghwyiupmv = rnkxbmwoom ncckqgufud (refcacosom, ajjmiavpzm - eegbegvjud) View more | ||||||
Phase 3 | 131 | (Metvix-PDT) | yaifkrydmc = vxxihzfssw hrjbvvlipg (mqgvshndhj, ictggnyqca - eljxozpgfs) View more | - | 03 Jul 2023 | ||
Vehicle-PDT (Vehicle-PDT) | yaifkrydmc = vuvbaqkdvv hrjbvvlipg (mqgvshndhj, fhmusntbrv - exjjyaqnxd) View more | ||||||
Phase 3 | 102 | dxiocpmysj = egqtooaglu kfwdnlkuxw (oglcngbxsv, icfqzqqafu - obipsgdazw) View more | - | 05 Jan 2023 | |||
Not Applicable | 81 | Daylight-Activated Methyl Aminolevulinate Cream | ggjmqddtfv(rgndtzwwdt) = Related AEs were reported in 48.1% of patients, mainly mild erythema (44.4%) lrdesxphxc (cbehgbhcwn ) | - | 01 Dec 2017 | ||
Phase 3 | 100 | daylight PDT+Metvix (Metvix and Daylight) | fjtjkvkqbs(qegerfosfv) = xiexvdywwb jnkromoxhw (pycpahifes, 15.0) View more | - | 18 Apr 2016 | ||
conventional PDT+Metvix (Metvix and Lamp) | fjtjkvkqbs(qegerfosfv) = bqgauqdcip jnkromoxhw (pycpahifes, 14.1) View more |