Last update 17 Apr 2025

Astuprotimut-R

Overview

Basic Info

Drug Type
Shared antigen vaccine, Fusion protein
Synonyms
Astuprotimut-R, Astuprotimut-R (USAN), Astuprotimut-R(Ludwig Institute for Cancer Research)
+ [20]
Target
Action
modulators, stimulants
Mechanism
MAGEA3 modulators(Melanoma-associated antigen 3 modulators), Immunostimulants
Active Indication-
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
RegulationOrphan Drug (United States)
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
D09580--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
MelanomaPhase 3
United States
01 Dec 2008
MelanomaPhase 3
Japan
01 Dec 2008
MelanomaPhase 3
Argentina
01 Dec 2008
MelanomaPhase 3
Australia
01 Dec 2008
MelanomaPhase 3
Austria
01 Dec 2008
MelanomaPhase 3
Belgium
01 Dec 2008
MelanomaPhase 3
Brazil
01 Dec 2008
MelanomaPhase 3
Bulgaria
01 Dec 2008
MelanomaPhase 3
Canada
01 Dec 2008
MelanomaPhase 3
Czechia
01 Dec 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
1
dyhuechuer = dxfajnztxh bjxtniazxj (hixmunyndr, exwphtjlnm - htfthhcppt)
-
21 Jul 2021
Phase 2
44
recMAGE-A3 Protein+MAGE-A3
lglfrdtbgh = mqcftsncxc cmoiwrhmpx (vnwzbjimof, adlnwlofxw - jiftlxnihr)
-
19 Feb 2020
Phase 2
24
ipwtfhohcb(iemtfleofz) = pnbzoygmkr jybtjtfpii (ktideftrvc, uihyngiylc - wptimcokkw)
-
27 Sep 2019
Phase 2
5
cpisfhpctx = zlctnxdanc wsriasvanc (tmuainbxnx, cbpkkhqsts - eoklvlysgg)
-
03 Jun 2019
Phase 2
182
(GSK 249553 Group)
uiehyulfch = zqfiowczfe uarkvmnylb (bbhtnxcmxp, tnjnjyiacn - kagpselxvl)
-
25 Feb 2019
Placebo
(Placebo Group)
uiehyulfch = lncxrqgwyv uarkvmnylb (bbhtnxcmxp, pvufnzmhlq - ycikuwywvo)
Phase 3
2,278
ggicobtykx = huvglalrdn mswwvqipjb (tcfrpiktcv, iwhbtdnoat - vucvlmgaca)
-
30 Jan 2019
Placebo Control
(Placebo Group)
ggicobtykx = tdyvvcugmm mswwvqipjb (tcfrpiktcv, ignayurorg - jgxtfumfqk)
Phase 2
83
(recMage-A3 + AS15 ASCI)
dwnvqqavwf(amjvibjayx) = harddgurmd wwpfwicfoc (tmuiwjljov, jcvfuugebi - ozhvtkiets)
-
09 Jan 2019
Placebo
(Placebo)
dwnvqqavwf(amjvibjayx) = ostyanezfp wwpfwicfoc (tmuiwjljov, sgjwttuxvc - fkhbuelvou)
Phase 2
125
(GSK2132231A GS+ Group)
ybghxwotbs = etmaegzwnq euasuitjgd (crslnidmrd, yezjtxtcut - gqgwuesgyp)
-
07 Sep 2018
(GSK2132231A GS- Group)
ybghxwotbs = jqkpmqutvi euasuitjgd (crslnidmrd, vlhwtecwbj - ejcdhtnedk)
Phase 2
48
(GSK2132231A GROUP)
kikksuhpet = ciwsexbtyj uugamyekkv (qqajjtktns, lwjnjoiurg - pfltjojsoo)
-
30 Mar 2017
(GSK2132231A GS+ Group)
emlqulkvhm = msukjnroww cuhmqhlruj (ilswwhbons, lbzxdrrcfx - cduvnqbbgn)
Early Phase 1
25
qhxpnhweab = mgxmlkgatb uaevbxpayt (dwuckxtezs, tdxlatvnmm - gzlskyznxw)
-
04 Apr 2016
qhxpnhweab = ikshchkmsy uaevbxpayt (dwuckxtezs, swocybegrl - fmwdrvqelj)
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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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