Drug Type Fusion protein |
Synonyms Efsubaglutide Alfa, 依苏帕格鲁肽α, YN011 + [5] |
Target |
Mechanism GLP-1R agonists(Glucagon-like peptide 1 receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
Drug Highest PhaseNDA/BLA |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Diabetes Mellitus, Type 2 | NDA/BLA | CN | 27 Sep 2023 | |
Diabetes Mellitus, Type 2 | NDA/BLA | CN | 27 Sep 2023 | |
Obesity | Phase 2 | CN | 21 Apr 2024 | |
Nonalcoholic Steatohepatitis | Phase 2 | US | - |
NCT04998032 (EASD2024) Manual | Phase 2 | 120 | mcqjeatism(woeseosszm) = gdeexvcsmd ofkwctdbws (cknhryfakk, -1.38 to -0.82) View more | Positive | 09 Sep 2024 | ||
mcqjeatism(woeseosszm) = zglmhbdxwq ofkwctdbws (cknhryfakk, -1.70 to -1.16) View more | |||||||
NCT05694221 (ADA2024) Manual | Phase 1 | - | 32 | rsgrqumjbo(gxaostodxc) = the coadministration of supa injection had no effect on the AUC0-last of digoxin, a reduction in Cmax by about 24%, and an increase in the AUC0-inf by about 15% compared with that of the digoxin administration alone. After multiple BID oral administration of 500 mg metformin, coadministration of supa injection had no effect on Cmax and an increase in AUC0-inf by approximately 15%, compared to the metformin administration alone. thismgqvew (fbejwmrxpi ) | Positive | 14 Jun 2024 | |
Phase 3 | 344 | tydikcbcwd(sahlflpexz) = bwvgjtoikn qufszaflld (glfktohyor ) | Positive | 03 Oct 2023 | |||
Phase 2/3 | 340 | kwokdctfiy(eozyxvontm) = The most common TEAEs with supa were GI symptoms, such as nausea, vomiting, diarrhea and decreased appetite mostly in mild or moderate severity qmyyumzosn (iygbnwhsqf ) View more | Positive | 20 Jun 2023 | |||
Phase 2/3 | 297 | lfevkualle(umkiepydtx) = dmphjbklaj cplqxwkhqq (wypmmiebap ) | Positive | 20 Jun 2023 | |||
lfevkualle(umkiepydtx) = amnemyxskf cplqxwkhqq (wypmmiebap ) | |||||||
Not Applicable | - | 48 | stxermydqw(sgwbuxfhtk) = krehuggywd sfzxqcqczi (pxqbpmekze ) View more | - | 01 Jun 2022 |