Background: Creatine supplementation is an effective ergogenic nutrient for athletes, as well as people for people starting a health or fitness program. Resistance training previously been identified as an important method of increasing muscle mass and strength among people, specially in people with cancer to avoid sarcopenia. The potential of creatine supplementation for adaptations produced by strength training in cancer patients are still unknown.
Objective: the primary aim of this study is to evaluate the effectiveness of a 16-week supervised resistance training program intervention with and without creatine supplementation in patients with breast cancer.
Methods: A multicentre, randomized, double-blind, placebo-controlled study designed to evaluate the effects of creatine supplementation in addition to resistance training in breast cancer patients. Patients will be randomly assigned to 3 groups: a control group (CG) and two experimental groups. The first resistance training group (RG) will perform resistance training, while the second resistance-creatine experimental group (RCG) will perform the same resistance training as the RG and will also receive a 5 g/day supplementation of creatine for the duration of the exercise the 16-week intervention. RG participants will follow the same daily dosing protocol, but in their case, with dextrose/maltodextrin. Resistance training will be a 16-week supervised workout that will consist of a series of resistance exercises (leg press, knee extension, knee bends, chest press, sit-ups, back extensions, pull-ups, and shoulder press) that involved the largest muscle groups of the body and will be performed three times a week on non-consecutive days. Both the RG and the RCG will receive a supplement of soluble protein powder (20-30 g) daily.
Discussion: The results of this intervention will help to better understand the potential of non-pharmacological treatment for improving strength and wellbeing values in breast cancer patients with and without creatine supplementation.

Start Date08 Apr 2024

Sponsor / Collaborator

University of Deusto

[+2]

CTRI/2024/02/063205 / Not yet recruitingPhase 2

A Randomized, Controlled Clinical Study on Creatine Monohydrate Supplement: Pharmacokinetics, Bioavailability, Safety and Efficacy in Enhancing Strength, Power, Muscle volumization,Energy, and Lean Body Mass in Active Males. - NA

Start Date03 Mar 2024

Sponsor / Collaborator

Lasons India Private Limited

DRKS00032563 / SuspendedNot Applicable

CreAtine iN Post-COVID – Intervention to mitigate postviraL fatiguE - CANDLE

Start Date01 Oct 2023

Sponsor / Collaborator-

100 Clinical Results associated with Creatine monohydrate

100 Translational Medicine associated with Creatine monohydrate

100 Patents (Medical) associated with Creatine monohydrate

3,422

Literatures (Medical) associated with Creatine monohydrate

01 Mar 2024·Synthetic and systems biotechnology

Efficient biosynthesis of creatine by whole-cell catalysis from guanidinoacetic acid in Corynebacterium glutamicum

Article

Author: Li, Jingyuan ; Deng, Yang ; Zhu, Yuqi ; Liu, Yanfeng ; Wei, Guoqing ; Chen, Jian ; Sun, Pengdong ; Li, Chunjian

Creatine is a naturally occurring derivative of an amino acid commonly utilized in functional foods and pharmaceuticals. Nevertheless, the current industrial synthesis of creatine relies on chemical processes, which may hinder its utilization in certain applications. Therefore, a biological approach was devised that employs whole-cell biocatalysis in the bacterium Corynebacterium glutamicum, which is considered safe for use in food production, to produce safe-for-consumption creatine. The objective of this study was to identify a guanidinoacetate N-methyltransferase (GAMT) with superior catalytic activity for creatine production. Through employing whole-cell biocatalysis, a gamt gene from Mus caroli (Mcgamt) was cloned and expressed in C. glutamicum ATCC 13032, resulting in a creatine titer of 3.37 g/L. Additionally, the study employed a promoter screening strategy that utilized nine native strong promoters in C. glutamicum to enhance the expression level of GAMT. The highest titer was achieved using the P₁₆₇₆ promoter, reaching 4.14 g/L. The conditions of whole-cell biocatalysis were further optimized, resulting in a creatine titer of 5.42 g/L. This is the first report of successful secretory creatine expression in C. glutamicum, which provides a safer and eco-friendly approach for the industrial production of creatine.

01 Feb 2024·Archives of gerontology and geriatrics

The association between methylmalonic acid, a biomarker of mitochondria dysfunction, and phenotypic age acceleration: A population-based study

Article

Author: Liu, Dan ; Cao, Bing ; Xue, Yu

Phenotypic age acceleration (PAA) is a sensitive marker of biological aging. Circulating methylmalonic acid (MMA) is a novel biomarker of mitochondrial dysfunction and has been associated with age-related disorders. Our study aimed to investigate to what extent circulating MMA was associated with PAA, and whether the association was independent of vitamin B12 status and renal function in the general population. We analyzed cross-sectional data from 13,023 participants across a wide age range (mean age: 38.9 years, range: 12 - 85 years, 51.1% women) from the US National Health and Nutrition Examination Survey (NHANES). PAA was calculated based on the published algorithm. Linear regression models were performed to assess the association between circulating MAA and PAA. Only 31% of the variation in MMA levels was explained by age, sex, race/ethnicity, social economic status, vitamin B12 status, and renal function. Per unit increase in circulating MAA (1.0 nmol/L) was associated with 1.59 years increase in PAA (β = 1.59, 95% CI: 1.17, 2.00, p < 0.001) after adjusting for multiple confounders. Importantly, PAA increased with circulating MMA levels independent of vitamin B12, creatine, and homocysteine levels. The association was more pronounced in subgroups of age ≥ 65 years, women, underweight, vitamin B12 < 400 μmol/L, and homocysteine ≥ 10 μmol/L. The association was much stronger among participants with cardiovascular diseases (CVDs) than without CVDs. In conclusion, our current population-based study showed that mitochondria-derived circulating MMA was associated with increased phenotypic age acceleration in the general population.

01 Feb 2024·Nutrition (Burbank, Los Angeles County, Calif.)

Prevalence of sports supplements consumption and its association with food choices among female elite football players

Article

Author: Planells, Elena ; Sánchez-Oliver, Antonio Jesús ; Gamarra-Morales, Yenifer ; Pérez, Andrea Baena ; Vázquez-Lorente, Héctor ; Herrera-Quintana, Lourdes ; Molina-López, Jorge

OBJECTIVES:

The present study aimed to 1) investigate the consumption of Sports Supplements (SSs) among female elite football players, 2) evaluate the influence of age on SS consumption, and 3) determine the relationship between the consumption of SSs and dietary choices among elite football players.

METHODS:

A total of 126 female football players of Primera Iberdrola and Reto Iberdrola who participated in this descriptive, observational, and cross-sectional study completed a self-administered questionnaire on SSs and the Athletes' Food Choices Questionnaire.

RESULTS:

Overall, 84.1% of participants consumed supplements, mainly for improved sports performance (68.3%) and health (34.1%). The main sources of purchase were the Internet (34.9%) and specialized shops (23.8%), and players were commonly advised by a dietitian-nutritionist to use SSs (56.3%). The SSs most often consumed included whey protein (30.2%), sports drinks (28.6%), creatine monohydrate (28.6%), sports bars (27.8%), and caffeine (27.8%). Older players consumed more supplements at the time of data compilation. Players predominantly acquired these supplements by using the Internet and reported benefits from their use (all P ≤ 0.036). Additionally, players who consumed SSs conveyed more concern about their food choices.

CONCLUSIONS:

A high prevalence of female football players consumed SSs, particularly SSs supported by robust scientific evidence. Older players had higher supplement consumption rates. The use of SSs was related to food choices through nutritional characteristics of foods, knowledge about health and nutrition, weight control with the help of food, and the performance benefits players could acquire.

News (Medical) associated with Creatine monohydrate

12 Dec 2023

·www.businesswire.com

WHOOP Announces Its “Year In Review” Celebrating That 2023 Was the Year Human Performance Became a Lifestyle

BOSTON--( BUSINESS WIRE )-- WHOOP , the human performance company, today released its annual Year in Review , highlighting the ways members unlocked their healthy obsessions in 2023, and identifies health and wellness patterns for 2024. The WHOOP community increased its commitment to their overall health and fitness and gained invaluable insights across Sleep, Strain, Recovery, and Stress, as WHOOP turns a dynamic understanding of the body into a healthy obsession, made possible by its latest innovations including Stress Monitor , Strength Trainer , and WHOOP Coach . The past year revealed that the biggest trends in health and wellbeing were centered on lifestyle shifts aiming to optimize performance. From changes in alcohol consumption, to the rise of new recovery behaviors like ice baths and red light therapy, 2023 saw an influx of circadian, nutritional, longevity, and health promoting habits. WHOOP data shows that even the smallest behavioral changes can have a big impact on the body and mind. “‘Year in Review’ is one of our favorite features to launch each year,” said Will Ahmed, Founder and CEO of WHOOP. “It's an important way to celebrate our members’ accomplishments and reflect on changing trends around the world.” Recovery - The best new buzz comes from ice baths, not booze. Alcohol consumption is down. WHOOP members consumed alcohol less frequently in 2023, but when they did, they consumed more, with an average of three drinks per sitting. Ice baths for recovery have shown a strong increase in popularity, as they can help reduce muscle soreness after intense workouts, aid in recovery by constricting blood vessels and decreasing metabolic activity. They may also release endorphins that can improve mood and energy. Red light therapy was also popular with the WHOOP community and helps improve Recovery as it’s believed that red light may increase production of melatonin, ultimately enhancing sleep. A strong Recovery is simple . There’s no need for elaborate Recovery routines or the latest gadgets. Behaviors that helped Recovery this year include strong sleep performance, consuming caffeine and implementing consistent wake times. Behaviors that hinder Recovery are consuming alcohol, having a fever, or excessive Strain. Sex and Recovery: Engaging in sexual activity can contribute to Recovery by reducing stress through the release of endorphins and oxytocin, which may help lower cortisol levels and promote relaxation, potentially leading to improved Recovery scores. The countries where WHOOP members had the most sex in 2023: U.S., Australia, Canada, Denmark, Netherlands Within the U.S., the states where members have the most sex are: Utah, Oklahoma, Alabama, Idaho, Nevada Stress can negatively impact recovery by increasing resting heart rate (RHR) and decreasing heart rate variability (HRV), key indicators WHOOP uses to calculate the Recovery score. Modalities such as breathwork and meditation are top ways WHOOP members managed stress this year. Sleep Hygiene - less can be more, when quality is enhanced. In 2023, WHOOP members didn’t get more sleep, but they found ways to get better sleep. More than half of WHOOP members (52%) tapped WHOOP Coach for individualized recommendations on ways to improve their quality of sleep. When members got morning sunlight, compared to the days they did not, their sleep consistency was higher and they got more sleep, averaging an additional 14 minutes per week. When members practiced daylight eating (consumed all meals during daylight hours), compared to the days they did not, their sleep consistency was also higher and they achieved more quality sleep, averaging an additional 42 minutes per week. Catching zzz's On average, global WHOOP members achieved: Average restorative sleep: 40% Average hours of sleep: 7 Average sleep efficiency: 89% Early birds and Night owls Average bedtime and wake time by country: Earliest bedtime: Australia 10:46 p.m., Latest Qatar 1:50 a.m. Earliest wake time: South Africa 6:40 a.m., Latest Qatar 9:38 a.m. Sleep is cultural: The city that never sleeps is Dubai – but in locations known for nightlife, sleep is also poor (Las Vegas, NV; Miami, FL) Strain - Optimizing Fitness Goes Beyond the Gym When it comes to enhancing performance around Strain and activity, proper nutrition plays a pivotal role. The top 1% of Strain earners (defined as those members with the highest average Strain) log vegetarian, vegan, and kosher diets more than others. On average, these members are the age of 45. WHOOP members reported using more creatine (+41%) as part of their supplement intake. Protein consumption has also seen an increase in 2023 (+38%). Activities with multipurpose benefits are gaining popularity. Rucking targets Zone 2 training , which is done at 60-70% of max heart rate, allowing the body to build an aerobic base, enhancing endurance, optimizing fitness, and unlocking performance gains. It’s typically done outdoors where members also reap the benefits of sunlight. Recreational activities are on the rise as people enjoy team fitness. Those that have seen strong adoption in 2023 include pickleball, soccer, cricket, rugby and paddle tennis. The newest health ambassadors aren’t athletes – they’re performers Stage performance also increased in 2023, with 19% more WHOOP members logging it as a Strain activity year-over-year. Many of the world’s top artists rely on WHOOP to help them choose healthier habits, optimize sleep and travel schedules to be at their best, including record producer, songwriter and DJ Zedd . “Our community achieved a lot in 2023, and we’re confident that WHOOP will help members achieve even more next year,” said Ahmed. “This feature arrives at a perfect time as our members reflect on their goals and get ready to begin 2024 with new ambitions. WHOOP will be there to help.” To access and review the WHOOP Community Year in Review , go to: whoop.com/2023-year-in-review . Individual, personalized Year in Review reports will be available to members in the WHOOP app. Now through December 18, WHOOP is running its Holiday Sale. For a limited time, consumers can take advantage of 10% off prepaid memberships; 12 months for $215 or 24 months for $359. To give the gift of WHOOP this holiday season, go to www.whoop.com . To make it even more convenient than ever before to access WHOOP, it is available for purchase on Amazon.com , as well as at Best Buy and Dick’s Sporting Goods . WHOOP is currently offering a one-month free trial to help everyone start their journey, available at www.whoop.com . ABOUT WHOOP WHOOP, the human performance company, offers a wearable health and fitness coach to help people achieve their goals. The WHOOP membership provides best-in-class wearable technology, actionable feedback, and recommendations across recovery, sleep, training, and health. WHOOP serves professional athletes, Fortune 500 CEOs, executives, fitness enthusiasts, military personnel, frontline workers, and anyone looking to improve their performance. WHOOP Unite is a comprehensive solution dedicated to supporting organizations across a wide range of industries with coaching, organizational insights, and health programs. Studies show WHOOP can positively change behavior, increase sleep, and improve physiological biomarkers. Founded in 2012, WHOOP is based in Boston and has raised more than $400 million in venture capital. The latest round of financing made WHOOP the world's most valuable standalone wearables company. Visit www.whoop.com for more information and connect with WHOOP on Instagram , Twitter , Facebook , LinkedIn , and YouTube .

05 Oct 2023

·www.prnewswire.com

Bizz Energy Is a Clean, Mean Way to Beat the Modern Midday Slump

The Energy Drink Formula Unleashes Unique Levels of Energy Whilst Avoiding Sugar Crashes and Unhealthy Ingredients FORT LAUDERDALE, Fla., Oct. 5, 2023 /PRNewswire/ -- The modern, remote-first work world may not have a consistent nine-to-five rhythm anymore. But that doesn't change the fact that people are still putting a lot of time into working their jobs. The Bureau of Labor Statistics reports that the average American worker clocks in at just over eight hours of labor per day (8.01, to be precise). That means, no matter when those work hours take place, they're going to extend over a significant portion of an individual's daily schedule. It also means it will involve a slump in energy and productivity at some point along the way. "Midday slumps may not always happen in the early afternoon anymore," says Gavin Jacono, founder of Bizz Energy, "But they happen at some point — and on a regular basis. If you start work at four in the morning, chances are you're going to lag after breakfast or in the late morning. If you start at noon, you'll feel tired before dinner." Northwestern Medicine points out that the biggest reason for this energy slump is that it's a predictable part of every individual's circadian cycle. However, the medical site adds that things like sleep disorders, stress, and even poor eating habits can also contribute to a slowdown in the middle of the workday. When that happens, many people turn to energy drinks as a solution — but Jacono points out that traditional energy drink formulas don't really solve the problem. "Those classic formulas use sugar, high fructose corn syrup, or aspartame. They give you a quick boost, but it's often followed by a crash — usually before your work day ends, which only means you're kicking the productivity issue down the road. And your body has to work through all of those unhealthy chemicals and additives, too. That's why we created Bizz Energy. To turn unhealthy, short-term energy drinks into healthy, long-term productivity and health solutions." Bizz Energy replaces unwanted ingredients with healthy alternatives. Each 12 oz can contains a clean shot of 200 mg of caffeine along with a punchy nutritional combination called the SuperTurk® blend. This includes an innovative soluble form of Turkesterone along with creatine, essential amino acids, L-citrulline, L-theanine, L-carnitine, niacin, and biotin. The result of this revolutionary combination is an energy drink that doubles as a nutritional supplement. It helps boost energy without a sugar crash while also stimulating metabolism and helping build muscle and strength. This makes it a clean, mean way to beat a midday slump — no matter when it might take place. About Bizz Energy Bizz Energy was founded by Gavin Jacono. The fitness and nutrition fanatic hails from New York City and is obsessed with boxing, weightlifting, and soccer. As an aspiring 17-year-old entrepreneur, Jacono launched Bizz Energy as a way to create the ultimate energy drink he had always wanted to fuel his athletic pursuits. Along with a potent dose of caffeine, the Bizz Energy formula taps into a unique form of soluble Turkesterone. It is delicious, clean, and effective. Learn more at bizzenergy.com. Media Contact: Gavin Jacono 516-637-8701 [email protected] SOURCE Bizz Energy

17 Oct 2022

·www.prnewswire.com

The Vitamin Shoppe's BodyTech® Sports Nutrition Brand and Warner Bros. Consumer Products Launch Exclusive Flavor Collaborations Inspired by Characters from the DC Universe including Superman, Batman, Wonder Woman, Black Adam and More

The license agreement brings flavor innovation plus the epic excitement of iconic DC Super Heroes and Super-Villains to BodyTech's lineup of premium protein, pre-workout, and sports nutrition products SECAUCUS, N.J., Oct. 17, 2022 /PRNewswire/ -- It's not a bird. It's not a plane. It's The Vitamin Shoppe's mightiest collaboration yet: Sports nutrition inspired by the DC™ Universe. The Vitamin Shoppe, an omnichannel specialty retailer of nutritional products, and Warner Bros. Consumer Products (WBCP) today announced the launch of DC™ flavors by BodyTech®, an exclusive range of protein, pre-workout, creatine, and other premium supplements inspired by Super Heroes and Super-Villains of the DC Universe. Continue Reading New BodyTech sports nutrition formulas unite flavor innovation with the epic excitement of iconic DC Super Heroes and Super-Villains from the DC Universe, including Superman, Batman, Wonder Woman, Black Adam and more. Under the long-term license agreement with WBCP, a series of innovative new flavors unites the epic excitement of iconic characters such as Superman™, Batman™, Wonder Woman™, The Flash™, The Joker™, and Black Adam™ with the best-in-class sports nutrition formulas of BodyTech and BodyTech Elite. Sharon Leite, CEO of The Vitamin Shoppe, commented: "As lifetime fans of these legendary characters that have helped shape popular culture for decades, all of us at The Vitamin Shoppe are thrilled to partner with the exceptional Warner Bros. Consumer Products and DC teams. The heroic action, vast creativity, and indelible impact on our collective imaginations of Super Hero stories – like Superman, Batman, Wonder Woman and Black Adam – have undoubtedly driven the fitness goals and aspirations of many BodyTech customers. This compelling collaboration offers consumers unique new flavors while bringing the fun and excitement of the DC Universe into any Super Hero fan's sports nutrition regimen, giving them the opportunity to fuel their own origin story." Each of the new DC™ x BodyTech® flavors in the launch lineup is designed to match the unique personality and super powers of its respective DC character, while maintaining the trusted quality and performance of The Vitamin Shoppe's best-selling BodyTech and BodyTech Elite premium formulas. The range is exclusively available in over 700 locations of The Vitamin Shoppe and Super Supplements stores, and on , with products including: Black Adam™ Black Cherry BodyTech Elite Nitrulline powder, to support massive pumps and endurance. Wonder Woman™ Sherbet BodyTech Whey Isolate, to support muscle growth and recovery. The Flash™ Lightning Lemonade BodyTech Flash Point, to support pre-workout energy and focus. The Joker™ Candy BodyTech Energized Critical Aminos, to support daily energy and recovery support. Superman™ Kryptonite™ Krusher BodyTech Elite Ultimate EAA, to support muscle building and stim-free focus. Batman™ Gotham City™ Grape BodyTech Elite Micronized Creatine Monohydrate, to support strength training and muscle mass. Additional products, flavors, and DC Universe Super Hero and Super-Villain character collaborations will be unveiled as part of this exclusive assortment in the future. For more information about The Vitamin Shoppe, visit , and for more information about DC, visit . About The Vitamin Shoppe® Lifelong Wellness Starts Here™. The Vitamin Shoppe®, a subsidiary of Franchise Group Inc. (NASDAQ: FRG), is a global, omnichannel specialty retailer and wellness lifestyle Company with the mission of providing customers with the most trusted products, guidance, and services to support them on their journeys of lifelong wellness. Based in Secaucus, New Jersey, the Company offers a comprehensive assortment of nutritional solutions, including vitamins, minerals, specialty supplements, herbs, sports nutrition, homeopathic remedies, green living products, and natural beauty products. In addition to carrying products from approximately 700 national brands, The Vitamin Shoppe offers products from its proprietary brands within its owned and wholesale channels, including: The Vitamin Shoppe®, Vthrive The Vitamin Shoppe™, BodyTech®, BodyTech® Elite, fitfactor™, fitfactor KETO™, plnt®, ProBioCare®, True Athlete®, and TrueYou™. In the U.S., the Company conducts business through over 700 company-operated retail stores under The Vitamin Shoppe and Super Supplements™ banners, and via its website, . The company is expanding its retail footprint via an innovative, omnichannel franchising model and opened its first franchise store in 2022. Globally, The Vitamin Shoppe serves customers in select Asia, South America, and Central America markets through local omnichannel partners. About Warner Bros. Consumer Products Warner Bros. Consumer Products (WBCP), part of Warner Bros. Discovery Global Brands and Experiences, extends the company's powerful portfolio of entertainment brands and franchises into the lives of fans around the world. WBCP partners with best-in-class licensees globally on an award-winning range of toys, fashion, home décor, and publishing inspired by Warner Bros.' biggest franchises from DC, Wizarding World, Looney Tunes, Hanna-Barbera, Game of Thrones, Cartoon Network and Adult Swim. With innovative global licensing and merchandising programs, retail initiatives, and promotional partnerships, WBCP is one of the leading licensing and retail merchandising organizations in the world. About DC DC, a Warner Bros. Discovery Company, creates iconic characters, enduring stories, and immersive experiences that inspire and entertain audiences of every generation around the world and is one of the world's largest publishers of comics and graphic novels. As a creative division, DC is charged with strategically integrating its stories and characters across film, television, consumer products, home entertainment, interactive games, and the DC Universe Infinite digital subscription service and community engagement portal. For more information visit dc.com. SOURCE The Vitamin Shoppe

Collaborate

100 Deals associated with Creatine monohydrate

External Link

KEGG	Wiki	ATC	Drug Bank
-	Creatine monohydrate	-	DB00148

R&D Status

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Amyotrophic Lateral Sclerosis	Phase 3	US	Avicena Group, Inc.	01 Jun 2003
Parkinson Disease	Phase 3	-	Avicena LLCStartup	-
Charcot-Marie-Tooth Disease	Phase 1	US	Avicena Group, Inc.	25 Jan 2006
Muscular Dystrophies	Phase 1	US	Avicena Group, Inc.	25 Jan 2006

Clinical Result

Indication

Phase

Evaluation

View All Results

Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


Pubmed	Not Applicable	Depressive Disorder	35	Creatine monohydrate 6g daily	xcaypfrhxe(hqyksqnpoh) = No clinically relevant physical side-effects were reported or observed yawdpahezh (brozlevxha ) View more	Positive	01 Feb 2018
				Placebo
NCT02356107 (CTgov)	Phase 4	Depressive Disorder, Major \| Depressive Disorder, Treatment-Resistant \| Hypoxia	15	Creatine monohydrate+5-hydroxytryptophan	ncmbkmfscr(dbxuauejja) = hjpphnplvc nbxltjocvv (fxevcvtdrs, nomsdazolp - mnouezxkzx) View more	-	04 Jan 2018
NCT02189915 (CTgov)	Not Applicable	Depressive Disorder \| Depression	14	Creatine Monohydrate	boqerrnbix(ctwhcuxzjo) = rverlvakgb rfbraizira (vfpyykxkdz, mndbyoctfm - bwjnutpdgs) View more	-	20 May 2016
NCT02188849 (CTgov)	Phase 3	Muscle Weakness	50	Resistance exercise training+Creatine (Creatine)	ylpksdlhpt(ylejjbdjho) = fioncqcyil fosrelzije (ylpgdcauab, tbzhquipah - fbyptttjxc) View more	-	30 Oct 2015
				Resistance exercise training (Placebo)	ylpksdlhpt(ylejjbdjho) = ldfnryayup fosrelzije (ylpgdcauab, pallzocppg - cumdtevkug) View more
NCT01257581 (CTgov)	Phase 2	Amyotrophic Lateral Sclerosis	60	creatine (Creatine 30gm)	akgtwmzduq(cfbtjcgpwc) = yhcfudanuo wvujhjbjah (ubozjfntsg, gtcokzfcpm - wwbpuhsnax) View more	-	04 Dec 2014
				Tamoxifen (Tamoxifen 40mg)	akgtwmzduq(cfbtjcgpwc) = spcyfawnww wvujhjbjah (ubozjfntsg, gjpepadpau - jvcvzkaszc) View more
NCT01412151 (CTgov)	Phase 2	Hodgkin's Lymphoma \| Huntington Disease	10	Creatine monohydrate	djbnpxrpxu(rxftyhkimm) = nqztamcpyy nnznexwgzy (mspmwdsnwh, ivslblixaw - sqwwnpjfic) View more	-	28 Dec 2012
NCT00348933 (CTgov)	Not Applicable	Angelman Syndrome	90	Metafolin+B12+Creatine+Betaine (Treatment (Metafolin/Creatine/Betaine/B12))	sznjhtrsdg(beznvcitww) = gkmdzpurcp cuxyogerbz (jsvihijcwr, hzukwmyeje - xxjfrofubs) View more	-	24 Sep 2012
				Metafolin (Treatment (Metafolin/Creatine/Betain/B12))	ukjdllwaps(fhlnaupclv) = mfuzjsirak xyxjhodcvp (qtyhctitjp, uceayowpgd - lznemqlixe) View more

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