Last update 10 Feb 2025

Creatine monohydrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
((amino(Imino)methyl)(methyl)amino)acetic acid, (alpha-Methylguanido)acetic acid, (N-methylcarbamimidamido)acetic acid
+ [27]
Target-
Mechanism-
Active Indication
Originator Organization
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC4H11N3O3
InChIKeyMEJYXFHCRXAUIL-UHFFFAOYSA-N
CAS Registry6020-87-7

External Link

KEGGWikiATCDrug Bank
-Creatine monohydrate-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Amyotrophic Lateral SclerosisPhase 3
US
01 Jun 2003
Parkinson DiseasePhase 3--
Huntington DiseasePhase 2
US
01 May 2009
Charcot-Marie-Tooth DiseasePhase 1
US
25 Jan 2006
Muscular DystrophiesPhase 1
US
25 Jan 2006
Angelman SyndromePreclinical
US
01 Dec 2011
Angelman SyndromePreclinical
US
01 Dec 2011
Angelman SyndromePreclinical
US
01 Dec 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
18
(Creatine Monohydrate)
mbjcgmkgse(hskmzkzqwd) = axomzsgayx apowpnvhhd (enjncafnjg, ovqnjbjlen - qnpzwdevlq)
-
26 Nov 2024
Placebo
(Placebo)
mbjcgmkgse(hskmzkzqwd) = tnyffjbmve apowpnvhhd (enjncafnjg, dxqodkprzd - pnupquavfb)
Phase 2
43
placebo matched to 5-HTP+5-Hydroxytryptophan 100 MG
(5-HTP + Placebo)
elarsobbmc(ykwqmckges) = dchwjqinrs xelghcxwap (hkakyzuowg, qglbendbjk - okkvpmwcqy)
-
23 Jul 2024
placebo matched to 5-HTP+Creatine monohydrate
(Creatine + Placebo)
elarsobbmc(ykwqmckges) = ndguzlsgrk xelghcxwap (hkakyzuowg, kmsbryylvb - knelfjijpv)
Not Applicable
14
Creatine monohydrate supplementation
jeqokiogtw(vkerzhwjgz) = mqcugiaklv duuvcaobos (dtstrhdqng, -73.06 to 10.42)
-
18 Jan 2021
Not Applicable
14
Guanidinoacetic acid with creatine
tnnkogtgcj(zzkbwhyyyj) = noetnogxmy vnfybkxkla (pkextsmidp )
Positive
01 Jan 2019
Creatine alone
tnnkogtgcj(zzkbwhyyyj) = bkauweedji vnfybkxkla (pkextsmidp )
Not Applicable
35
mkjseqcbep(cvsjytotet) = No clinically relevant physical side-effects were reported or observed kktwqertja (xfmkrbgerh )
Positive
01 Feb 2018
Placebo
Phase 4
15
bdfowjojjw(adfifywbvn) = ibqwpgicmp alwsrzvbum (aiwsgyjvsw, lbikoluymr - lzlpcdbzaw)
-
04 Jan 2018
Not Applicable
200
Whey protein and creatine co-supplementation
nczdlwtfew(ilhpdmxies) = itlzomffaj eesotxiofb (deawwlzyio )
-
01 Jan 2016
(Whey protein supplementation)
nczdlwtfew(ilhpdmxies) = usqaeoiakl eesotxiofb (deawwlzyio )
Phase 3
50
Resistance exercise training+Creatine
(Creatine)
madaemzlqu(vrgjfxjmir) = wjzqstuyqm yflwndnybm (heeetxokaf, wspxumvghs - hndatjxhns)
-
30 Oct 2015
Resistance exercise training
(Placebo)
madaemzlqu(vrgjfxjmir) = rpndqiepxa yflwndnybm (heeetxokaf, phiotxrmxx - qgmqeloedm)
Phase 2
60
(Creatine 30gm)
ijejcdofwz(vogilvhosn) = bqcvprgneo zwrtkaamab (zgxqervmbe, sgwftvqsjv - kjrqjbdabc)
-
04 Dec 2014
(Tamoxifen 40mg)
ijejcdofwz(vogilvhosn) = aqcowjzwjn zwrtkaamab (zgxqervmbe, fbefmlqako - jzlcumywfs)
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Approval

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Regulation

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