Investigating the effects of creatine supplementation on serum testosterone, dihydrotestosterone levels, and hair density in strength athletes: A double-blind clinical trial study

Start Date01 Oct 2024

Sponsor / Collaborator-

CTRI/2024/08/073021 / CompletedNot Applicable

A Double Blind, randomized, single center, comparative, two-treatment, two-period, crossover, oral bioavailability study to determine the effect of MuscleBlaze Creatine Monohydrate (CreAMP)TM 3.1 gm as compared to regular Creatine Monohydrate (micronized) 3.0 gm in adult healthy male subjects under fasting condition. - NIL

Start Date07 Sep 2024

Sponsor / Collaborator

Bright Lifecare Pvt Ltd.

100 Clinical Results associated with Creatine monohydrate

100 Translational Medicine associated with Creatine monohydrate

100 Patents (Medical) associated with Creatine monohydrate

3,850

Literatures (Medical) associated with Creatine monohydrate

31 Dec 2024·RENAL FAILURE

Exploring the relationship between creatine supplementation and renal function: insights from Mendelian randomization analysis

Article

Author: Hong, Minping ; Ling, Keng ; Jin, Liqin ; Zhou, Bing

BACKGROUND:

Creatine supplementation is ubiquitously consumed by fitness enthusiasts due to its perceived advantages in enhancing athletic performance. Although there is an increasing concern within this demographic regarding its possible impact on renal function, there is still a lack of rigorous scientific investigations into this alleged association.

METHODS:

Data were collected through an online survey on the participants' demographics, creatine usage and concerns related to renal function. The reliability and validity of the survey were assessed using SPSS software. A total of 1129 participants responded to the survey, and chi-square tests were utilized for data analysis. To explore the potential association between creatine levels (as the exposure) and renal function (as the outcome), we utilized open-access genetic databases, and Mendelian randomization (MR) techniques were used to confirm this correlation.

RESULTS:

Chi-square analysis revealed no significant association between creatine usage and renal function among the participants. Our MR analysis further supported this finding, demonstrating no significant association between creatine levels and six indicators assessing renal function (IVW, all with p values exceeding 0.05). Similar p values were consistently observed across other MR methods, confirming the absence of a statistical correlation.

CONCLUSIONS:

This MR study offers compelling evidence indicating that creatine levels are not statistically associated with renal function, suggesting the potential to alleviate concerns within the fitness community and emphasizing the significance of evidence-based decision-making when considering nutritional supplementation.

31 Dec 2024·Journal of the International Society of Sports Nutrition

Creatine supplementation protocols with or without training interventions on body composition: a GRADE-assessed systematic review and dose-response meta-analysis

Review

Author: Goudarzi, Kian ; Forbes, Scott C ; Ashtary-Larky, Damoon ; Bagheri, Reza ; Pashayee-Khamene, Fereshteh ; Asbaghi, Omid ; Dutheil, Fred ; Candow, Darren G ; Ghanavati, Matin ; Heidari, Zeinab

BACKGROUND:

Despite the robust evidence demonstrating positive effects from creatine supplementation (primarily when associated with resistance training) on measures of body composition, there is a lack of a comprehensive evaluation regarding the influence of creatine protocol parameters (including dose and form) on body mass and estimates of fat-free and fat mass.

METHODS:

Randomized controlled trials (RCTs) evaluating the effect of creatine supplementation on body composition were included. Electronic databases, including PubMed, Web of Science, and Scopus were searched up to July 2023. Heterogeneity tests were performed. Random effect models were assessed based on the heterogeneity tests, and pooled data were examined to determine the weighted mean difference (WMD) with a 95% confidence interval (CI).

RESULTS:

From 4831 initial records, a total of 143 studies met the inclusion criteria. Creatine supplementation increased body mass (WMD: 0.86 kg; 95% CI: 0.76 to 0.96, I² = 0%) and fat-free mass (WMD: 0.82 kg; 95% CI: 0.57 to 1.06, I² = 0%) while reducing body fat percentage (WMD: -0.28 %; 95% CI: -0.47 to -0.09; I² = 0%). Studies that incorporated a maintenance dose of creatine or performed resistance training in conjunction with supplementation had greater effects on body composition.

CONCLUSION:

Creatine supplementation has a small effect on body mass and estimates of fat-free mass and body fat percentage. These findings were more robust when combined with resistance training.

31 Dec 2024·Journal of the International Society of Sports Nutrition

High-dose short-term creatine supplementation without beneficial effects in professional cyclists: a randomized controlled trial

Article

Author: Valenzuela, Pedro L ; Lucia, Alejandro ; Barranco-Gil, David ; Górriz, Miguel ; Pagola, Itziar ; Alejo, Lidia B ; Revuelta, Carlos ; Ozcoidi, Laureano M

BACKGROUND:

Growing evidence supports the ergogenic effects of creatine supplementation on muscle power/strength, but its effects on endurance performance remain unclear. We assessed the effects of high-dose short-term creatine supplementation in professional cyclists during a training camp.

METHODS:

The study followed a double-blind, randomized parallel design. Twenty-three professional U23 cyclists (19 ± 1 years, maximum oxygen uptake: 73.0 ± 4.6 mL/kg/min) participated in a 6-day training camp. Participants were randomized to consume daily either a recovery drink (containing carbohydrates and protein) with a 20-g creatine supplement (creatine group, n = 11) or just the recovery drink (placebo group, n = 12). Training loads and dietary intake were monitored, and indicators of fatigue/recovery (Hooper index, countermovement jump height), body composition, and performance (10-second sprint, 3-, 6-, and 12-minute time trials, respectively, as well as critical power and W') were assessed as study outcomes.

RESULTS:

The training camp resulted in a significant (p < 0.001) increase of training loads (+50% for total training time and + 61% for training stress score, compared with the preceding month) that in turn induced an increase in fatigue indicators (significant time effect [p < 0.001] for delayed-onset muscle soreness, fatigue, and total Hooper index) and a decrease in performance (significant time effect [p = 0.020] for critical power, which decreased by -3.8%). However, no significant group-by-time interaction effect was found for any of the study outcomes (all p > 0.05).

CONCLUSIONS:

High-dose short-term creatine supplementation seems to exert no consistent beneficial effects on recovery, body composition or performance indicators during a strenuous training period in professional cyclists.

News (Medical) associated with Creatine monohydrate

12 Dec 2023

·www.businesswire.com

WHOOP Announces Its “Year In Review” Celebrating That 2023 Was the Year Human Performance Became a Lifestyle

BOSTON--( BUSINESS WIRE )-- WHOOP , the human performance company, today released its annual Year in Review , highlighting the ways members unlocked their healthy obsessions in 2023, and identifies health and wellness patterns for 2024. The WHOOP community increased its commitment to their overall health and fitness and gained invaluable insights across Sleep, Strain, Recovery, and Stress, as WHOOP turns a dynamic understanding of the body into a healthy obsession, made possible by its latest innovations including Stress Monitor , Strength Trainer , and WHOOP Coach . The past year revealed that the biggest trends in health and wellbeing were centered on lifestyle shifts aiming to optimize performance. From changes in alcohol consumption, to the rise of new recovery behaviors like ice baths and red light therapy, 2023 saw an influx of circadian, nutritional, longevity, and health promoting habits. WHOOP data shows that even the smallest behavioral changes can have a big impact on the body and mind. “‘Year in Review’ is one of our favorite features to launch each year,” said Will Ahmed, Founder and CEO of WHOOP. “It's an important way to celebrate our members’ accomplishments and reflect on changing trends around the world.” Recovery - The best new buzz comes from ice baths, not booze. Alcohol consumption is down. WHOOP members consumed alcohol less frequently in 2023, but when they did, they consumed more, with an average of three drinks per sitting. Ice baths for recovery have shown a strong increase in popularity, as they can help reduce muscle soreness after intense workouts, aid in recovery by constricting blood vessels and decreasing metabolic activity. They may also release endorphins that can improve mood and energy. Red light therapy was also popular with the WHOOP community and helps improve Recovery as it’s believed that red light may increase production of melatonin, ultimately enhancing sleep. A strong Recovery is simple . There’s no need for elaborate Recovery routines or the latest gadgets. Behaviors that helped Recovery this year include strong sleep performance, consuming caffeine and implementing consistent wake times. Behaviors that hinder Recovery are consuming alcohol, having a fever, or excessive Strain. Sex and Recovery: Engaging in sexual activity can contribute to Recovery by reducing stress through the release of endorphins and oxytocin, which may help lower cortisol levels and promote relaxation, potentially leading to improved Recovery scores. The countries where WHOOP members had the most sex in 2023: U.S., Australia, Canada, Denmark, Netherlands Within the U.S., the states where members have the most sex are: Utah, Oklahoma, Alabama, Idaho, Nevada Stress can negatively impact recovery by increasing resting heart rate (RHR) and decreasing heart rate variability (HRV), key indicators WHOOP uses to calculate the Recovery score. Modalities such as breathwork and meditation are top ways WHOOP members managed stress this year. Sleep Hygiene - less can be more, when quality is enhanced. In 2023, WHOOP members didn’t get more sleep, but they found ways to get better sleep. More than half of WHOOP members (52%) tapped WHOOP Coach for individualized recommendations on ways to improve their quality of sleep. When members got morning sunlight, compared to the days they did not, their sleep consistency was higher and they got more sleep, averaging an additional 14 minutes per week. When members practiced daylight eating (consumed all meals during daylight hours), compared to the days they did not, their sleep consistency was also higher and they achieved more quality sleep, averaging an additional 42 minutes per week. Catching zzz's On average, global WHOOP members achieved: Average restorative sleep: 40% Average hours of sleep: 7 Average sleep efficiency: 89% Early birds and Night owls Average bedtime and wake time by country: Earliest bedtime: Australia 10:46 p.m., Latest Qatar 1:50 a.m. Earliest wake time: South Africa 6:40 a.m., Latest Qatar 9:38 a.m. Sleep is cultural: The city that never sleeps is Dubai – but in locations known for nightlife, sleep is also poor (Las Vegas, NV; Miami, FL) Strain - Optimizing Fitness Goes Beyond the Gym When it comes to enhancing performance around Strain and activity, proper nutrition plays a pivotal role. The top 1% of Strain earners (defined as those members with the highest average Strain) log vegetarian, vegan, and kosher diets more than others. On average, these members are the age of 45. WHOOP members reported using more creatine (+41%) as part of their supplement intake. Protein consumption has also seen an increase in 2023 (+38%). Activities with multipurpose benefits are gaining popularity. Rucking targets Zone 2 training , which is done at 60-70% of max heart rate, allowing the body to build an aerobic base, enhancing endurance, optimizing fitness, and unlocking performance gains. It’s typically done outdoors where members also reap the benefits of sunlight. Recreational activities are on the rise as people enjoy team fitness. Those that have seen strong adoption in 2023 include pickleball, soccer, cricket, rugby and paddle tennis. The newest health ambassadors aren’t athletes – they’re performers Stage performance also increased in 2023, with 19% more WHOOP members logging it as a Strain activity year-over-year. Many of the world’s top artists rely on WHOOP to help them choose healthier habits, optimize sleep and travel schedules to be at their best, including record producer, songwriter and DJ Zedd . “Our community achieved a lot in 2023, and we’re confident that WHOOP will help members achieve even more next year,” said Ahmed. “This feature arrives at a perfect time as our members reflect on their goals and get ready to begin 2024 with new ambitions. WHOOP will be there to help.” To access and review the WHOOP Community Year in Review , go to: whoop.com/2023-year-in-review . Individual, personalized Year in Review reports will be available to members in the WHOOP app. Now through December 18, WHOOP is running its Holiday Sale. For a limited time, consumers can take advantage of 10% off prepaid memberships; 12 months for $215 or 24 months for $359. To give the gift of WHOOP this holiday season, go to www.whoop.com . To make it even more convenient than ever before to access WHOOP, it is available for purchase on Amazon.com , as well as at Best Buy and Dick’s Sporting Goods . WHOOP is currently offering a one-month free trial to help everyone start their journey, available at www.whoop.com . ABOUT WHOOP WHOOP, the human performance company, offers a wearable health and fitness coach to help people achieve their goals. The WHOOP membership provides best-in-class wearable technology, actionable feedback, and recommendations across recovery, sleep, training, and health. WHOOP serves professional athletes, Fortune 500 CEOs, executives, fitness enthusiasts, military personnel, frontline workers, and anyone looking to improve their performance. WHOOP Unite is a comprehensive solution dedicated to supporting organizations across a wide range of industries with coaching, organizational insights, and health programs. Studies show WHOOP can positively change behavior, increase sleep, and improve physiological biomarkers. Founded in 2012, WHOOP is based in Boston and has raised more than $400 million in venture capital. The latest round of financing made WHOOP the world's most valuable standalone wearables company. Visit www.whoop.com for more information and connect with WHOOP on Instagram , Twitter , Facebook , LinkedIn , and YouTube .

05 Oct 2023

·www.prnewswire.com

Bizz Energy Is a Clean, Mean Way to Beat the Modern Midday Slump

The Energy Drink Formula Unleashes Unique Levels of Energy Whilst Avoiding Sugar Crashes and Unhealthy Ingredients FORT LAUDERDALE, Fla., Oct. 5, 2023 /PRNewswire/ -- The modern, remote-first work world may not have a consistent nine-to-five rhythm anymore. But that doesn't change the fact that people are still putting a lot of time into working their jobs. The Bureau of Labor Statistics reports that the average American worker clocks in at just over eight hours of labor per day (8.01, to be precise). That means, no matter when those work hours take place, they're going to extend over a significant portion of an individual's daily schedule. It also means it will involve a slump in energy and productivity at some point along the way. "Midday slumps may not always happen in the early afternoon anymore," says Gavin Jacono, founder of Bizz Energy, "But they happen at some point — and on a regular basis. If you start work at four in the morning, chances are you're going to lag after breakfast or in the late morning. If you start at noon, you'll feel tired before dinner." Northwestern Medicine points out that the biggest reason for this energy slump is that it's a predictable part of every individual's circadian cycle. However, the medical site adds that things like sleep disorders, stress, and even poor eating habits can also contribute to a slowdown in the middle of the workday. When that happens, many people turn to energy drinks as a solution — but Jacono points out that traditional energy drink formulas don't really solve the problem. "Those classic formulas use sugar, high fructose corn syrup, or aspartame. They give you a quick boost, but it's often followed by a crash — usually before your work day ends, which only means you're kicking the productivity issue down the road. And your body has to work through all of those unhealthy chemicals and additives, too. That's why we created Bizz Energy. To turn unhealthy, short-term energy drinks into healthy, long-term productivity and health solutions." Bizz Energy replaces unwanted ingredients with healthy alternatives. Each 12 oz can contains a clean shot of 200 mg of caffeine along with a punchy nutritional combination called the SuperTurk® blend. This includes an innovative soluble form of Turkesterone along with creatine, essential amino acids, L-citrulline, L-theanine, L-carnitine, niacin, and biotin. The result of this revolutionary combination is an energy drink that doubles as a nutritional supplement. It helps boost energy without a sugar crash while also stimulating metabolism and helping build muscle and strength. This makes it a clean, mean way to beat a midday slump — no matter when it might take place. About Bizz Energy Bizz Energy was founded by Gavin Jacono. The fitness and nutrition fanatic hails from New York City and is obsessed with boxing, weightlifting, and soccer. As an aspiring 17-year-old entrepreneur, Jacono launched Bizz Energy as a way to create the ultimate energy drink he had always wanted to fuel his athletic pursuits. Along with a potent dose of caffeine, the Bizz Energy formula taps into a unique form of soluble Turkesterone. It is delicious, clean, and effective. Learn more at bizzenergy.com. Media Contact: Gavin Jacono 516-637-8701 [email protected] SOURCE Bizz Energy

17 Oct 2022

·www.prnewswire.com

The Vitamin Shoppe's BodyTech® Sports Nutrition Brand and Warner Bros. Consumer Products Launch Exclusive Flavor Collaborations Inspired by Characters from the DC Universe including Superman, Batman, Wonder Woman, Black Adam and More

The license agreement brings flavor innovation plus the epic excitement of iconic DC Super Heroes and Super-Villains to BodyTech's lineup of premium protein, pre-workout, and sports nutrition products SECAUCUS, N.J., Oct. 17, 2022 /PRNewswire/ -- It's not a bird. It's not a plane. It's The Vitamin Shoppe's mightiest collaboration yet: Sports nutrition inspired by the DC™ Universe. The Vitamin Shoppe, an omnichannel specialty retailer of nutritional products, and Warner Bros. Consumer Products (WBCP) today announced the launch of DC™ flavors by BodyTech®, an exclusive range of protein, pre-workout, creatine, and other premium supplements inspired by Super Heroes and Super-Villains of the DC Universe. Continue Reading New BodyTech sports nutrition formulas unite flavor innovation with the epic excitement of iconic DC Super Heroes and Super-Villains from the DC Universe, including Superman, Batman, Wonder Woman, Black Adam and more. Under the long-term license agreement with WBCP, a series of innovative new flavors unites the epic excitement of iconic characters such as Superman™, Batman™, Wonder Woman™, The Flash™, The Joker™, and Black Adam™ with the best-in-class sports nutrition formulas of BodyTech and BodyTech Elite. Sharon Leite, CEO of The Vitamin Shoppe, commented: "As lifetime fans of these legendary characters that have helped shape popular culture for decades, all of us at The Vitamin Shoppe are thrilled to partner with the exceptional Warner Bros. Consumer Products and DC teams. The heroic action, vast creativity, and indelible impact on our collective imaginations of Super Hero stories – like Superman, Batman, Wonder Woman and Black Adam – have undoubtedly driven the fitness goals and aspirations of many BodyTech customers. This compelling collaboration offers consumers unique new flavors while bringing the fun and excitement of the DC Universe into any Super Hero fan's sports nutrition regimen, giving them the opportunity to fuel their own origin story." Each of the new DC™ x BodyTech® flavors in the launch lineup is designed to match the unique personality and super powers of its respective DC character, while maintaining the trusted quality and performance of The Vitamin Shoppe's best-selling BodyTech and BodyTech Elite premium formulas. The range is exclusively available in over 700 locations of The Vitamin Shoppe and Super Supplements stores, and on , with products including: Black Adam™ Black Cherry BodyTech Elite Nitrulline powder, to support massive pumps and endurance. Wonder Woman™ Sherbet BodyTech Whey Isolate, to support muscle growth and recovery. The Flash™ Lightning Lemonade BodyTech Flash Point, to support pre-workout energy and focus. The Joker™ Candy BodyTech Energized Critical Aminos, to support daily energy and recovery support. Superman™ Kryptonite™ Krusher BodyTech Elite Ultimate EAA, to support muscle building and stim-free focus. Batman™ Gotham City™ Grape BodyTech Elite Micronized Creatine Monohydrate, to support strength training and muscle mass. Additional products, flavors, and DC Universe Super Hero and Super-Villain character collaborations will be unveiled as part of this exclusive assortment in the future. For more information about The Vitamin Shoppe, visit , and for more information about DC, visit . About The Vitamin Shoppe® Lifelong Wellness Starts Here™. The Vitamin Shoppe®, a subsidiary of Franchise Group Inc. (NASDAQ: FRG), is a global, omnichannel specialty retailer and wellness lifestyle Company with the mission of providing customers with the most trusted products, guidance, and services to support them on their journeys of lifelong wellness. Based in Secaucus, New Jersey, the Company offers a comprehensive assortment of nutritional solutions, including vitamins, minerals, specialty supplements, herbs, sports nutrition, homeopathic remedies, green living products, and natural beauty products. In addition to carrying products from approximately 700 national brands, The Vitamin Shoppe offers products from its proprietary brands within its owned and wholesale channels, including: The Vitamin Shoppe®, Vthrive The Vitamin Shoppe™, BodyTech®, BodyTech® Elite, fitfactor™, fitfactor KETO™, plnt®, ProBioCare®, True Athlete®, and TrueYou™. In the U.S., the Company conducts business through over 700 company-operated retail stores under The Vitamin Shoppe and Super Supplements™ banners, and via its website, . The company is expanding its retail footprint via an innovative, omnichannel franchising model and opened its first franchise store in 2022. Globally, The Vitamin Shoppe serves customers in select Asia, South America, and Central America markets through local omnichannel partners. About Warner Bros. Consumer Products Warner Bros. Consumer Products (WBCP), part of Warner Bros. Discovery Global Brands and Experiences, extends the company's powerful portfolio of entertainment brands and franchises into the lives of fans around the world. WBCP partners with best-in-class licensees globally on an award-winning range of toys, fashion, home décor, and publishing inspired by Warner Bros.' biggest franchises from DC, Wizarding World, Looney Tunes, Hanna-Barbera, Game of Thrones, Cartoon Network and Adult Swim. With innovative global licensing and merchandising programs, retail initiatives, and promotional partnerships, WBCP is one of the leading licensing and retail merchandising organizations in the world. About DC DC, a Warner Bros. Discovery Company, creates iconic characters, enduring stories, and immersive experiences that inspire and entertain audiences of every generation around the world and is one of the world's largest publishers of comics and graphic novels. As a creative division, DC is charged with strategically integrating its stories and characters across film, television, consumer products, home entertainment, interactive games, and the DC Universe Infinite digital subscription service and community engagement portal. For more information visit dc.com. SOURCE The Vitamin Shoppe

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100 Deals associated with Creatine monohydrate

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KEGG	Wiki	ATC	Drug Bank
-	Creatine monohydrate	-	DB00148

R&D Status

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Amyotrophic Lateral Sclerosis	Phase 3	US	Avicena Group, Inc.	01 Jun 2003
Parkinson Disease	Phase 3	-	Avicena LLCStartup	-
Charcot-Marie-Tooth Disease	Phase 1	US	Avicena Group, Inc.	25 Jan 2006
Muscular Dystrophies	Phase 1	US	Avicena Group, Inc.	25 Jan 2006
Angelman Syndrome	Preclinical	US	Rady Children's Hospital-San Diego	01 Dec 2011
Angelman Syndrome	Preclinical	US	University of California	01 Dec 2011
Angelman Syndrome	Preclinical	US	National Institutes of Health	01 Dec 2011

Clinical Result

Indication

Phase

Evaluation

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Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


NCT04395183 (CTgov)	Phase 2	Depressive Disorder, Major	43	placebo matched to 5-HTP+5-Hydroxytryptophan 100 MG (5-HTP + Placebo)	rdjafzcmir(gbzlypwxsq) = zmdiwterkn qzdnbnhduk (nyfcbpgrgn, jveotbrfoo - dyfhotgofh) View more	-	23 Jul 2024
				placebo matched to 5-HTP+Creatine monohydrate (Creatine + Placebo)	rdjafzcmir(gbzlypwxsq) = bmpuokkuhe qzdnbnhduk (nyfcbpgrgn, fuljmsdhwe - xdcqtwvayh) View more
Pubmed	Not Applicable	Depressive Disorder	35	Creatine monohydrate 6g daily	aetbdyrcsk(meosjawkcq) = No clinically relevant physical side-effects were reported or observed dstfqtbiyc (qsjekwvxik ) View more	Positive	01 Feb 2018
				Placebo
NCT02356107 (CTgov)	Phase 4	Hypoxia \| Depressive Disorder, Major \| Depressive Disorder, Treatment-Resistant	15	Creatine monohydrate+5-hydroxytryptophan	xgxjvxzdbx(bxyrvboeno) = oygxvoodvi mmurrenhqd (ugmqtxywgo, lcgfiapbkt - dlnioecoyt) View more	-	04 Jan 2018
NCT02188849 (CTgov)	Phase 3	Muscle Weakness	50	Resistance exercise training+Creatine (Creatine)	zmjhurcykv(vtqdsrxhpf) = zwavjdobiz jxlvcbedvr (bwvscmtvqz, umxkhnfzic - zmgxplkurv) View more	-	30 Oct 2015
				Resistance exercise training (Placebo)	zmjhurcykv(vtqdsrxhpf) = ptvwhiciir jxlvcbedvr (bwvscmtvqz, xfdzpfdzkr - avaqxjsqwv) View more
NCT01257581 (SDALS-001, CTgov)	Phase 2	Amyotrophic Lateral Sclerosis	60	creatine (Creatine 30gm)	wchmwfxgvw(ufgreplssw) = xettpgajae tjbiakzhuf (nzsewrlvzx, sujcwtxchf - huhcjyaoiv) View more	-	04 Dec 2014
				Tamoxifen (Tamoxifen 40mg)	wchmwfxgvw(ufgreplssw) = hheqrmbyvo tjbiakzhuf (nzsewrlvzx, gnedzqmwli - igabevlzuy) View more
NCT01412151 (CREST-X, CTgov)	Phase 2	Hodgkin's Lymphoma \| Huntington Disease	10	Creatine monohydrate	enxnnglnsf(vvpowzyjcq) = zefuhreilm ngqoqkjfen (drrgfuoabt, ukgfbezmqy - yxjigjtxpg) View more	-	28 Dec 2012
NCT00348933 (CTgov)	Not Applicable	Angelman Syndrome	90	Metafolin+B12+Creatine+Betaine (Treatment (Metafolin/Creatine/Betaine/B12))	ultllrfujp(twduqrmmei) = fennmpbkgd upsyycwjfz (hncmacxgwy, fixzomvdsf - yhjxfageks) View more	-	24 Sep 2012
				Metafolin (Treatment (Metafolin/Creatine/Betain/B12))	erlqaobeea(rvifdyjxlo) = ardvdfqdou osowptzoqx (dofwxambrv, rmoijztayp - exbbqdjnny) View more
Pubmed \| J Gerontol A Biol Sci Med Sci	Not Applicable	-	-	Creatine monohydrate (CrM) supplementation	tnblyxqxdc(izmjszfxqc) = oniwtswssj kctzabqzxk (zockpzaqbr ) View more	Positive	01 Jan 2003
Pubmed \| Med Sci Sports Exerc	Not Applicable	Multiple Endocrine Neoplasia	-	Creatine supplementation	mriokfqlrb(jsauxzbtvi) = mfwqlxhcsj kvtnbkkfur (mtkrfmfstu ) View more	-	01 Dec 2001
				Creatine (Placebo)	mriokfqlrb(jsauxzbtvi) = wagpktnsyb kvtnbkkfur (mtkrfmfstu ) View more

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