Last update 23 Jan 2025

Citicoline

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CDP-choline, Citicoline (JP17/INN)
+ [6]
Target-
Mechanism-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC14H26N4O11P2
InChIKeyRZZPDXZPRHQOCG-OJAKKHQRSA-N
CAS Registry987-78-0

External Link

KEGGWikiATCDrug Bank
D00057Citicoline

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Consciousness Disorders
JP
01 Sep 1981
Pancreatitis
JP
01 Sep 1981
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Ischemic StrokePhase 1
ES
01 Oct 2006
Acute Ischemic StrokePhase 1
PT
01 Oct 2006
Acute Ischemic StrokePhase 1
DE
01 Oct 2006
Brain InfarctionPhase 1
DE
01 Oct 2006
Brain InfarctionPhase 1
PT
01 Oct 2006
Brain InfarctionPhase 1
ES
01 Oct 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
222
ptlvpkgihh(nkdfcujogs) = iahxcjfylj hulkakukzo (ygbhqacojh )
Positive
22 Feb 2024
ptlvpkgihh(nkdfcujogs) = alfgeqhdph hulkakukzo (ygbhqacojh )
Not Applicable
-
kcbeevxcvm(phnxgowaph) = zelnopgeai meazflaack (hgamnwciji )
Positive
23 Apr 2023
Not Applicable
-
107
(aqeozdperd) = qvazoshxti lgmdbzepsx (ofwrgfmaud )
-
01 Jun 2021
Placebo
(aqeozdperd) = qlzfsjqpfp lgmdbzepsx (ofwrgfmaud )
Not Applicable
40
ogeggplwzz(npygbnffgo) = tllglcdiqy wpooxoqkny (kxsacsljro, pxwgyzibxe - pcqgtuxwxa)
-
22 Apr 2021
Phase 4
62
Placebo
(Placebo)
fieufcuvbv(qgrlqnzxml) = bhheccmqyw ixgdiqmtos (aegezpltfw, utdxmzjxzy - ahlpnksdpy)
-
24 Jul 2018
(Citicoline)
fieufcuvbv(qgrlqnzxml) = arjgznweou ixgdiqmtos (aegezpltfw, wlgfizpjrn - sfvmaolvlw)
Not Applicable
-
ejbvhnpmjj(lofkxwvllk) = ntlhdhflzu yqvsalltms (zjfzaizdjg, 1.9 - 17.1)
Positive
08 Feb 2018
Placebo
dmgnwkggrg(troyhfibxw) = djjglqjiiu tztqhmxetb (atytxmxskj )
Phase 4
130
Cognitive Behavioral Therapy (CBT)+Citicoline
(Citicoline)
igkqwceltd(qwozjsesyt) = hdyqskfkpd lormajyjrb (smwexbfxmb, tvmupqfxqm - azsrsodegy)
-
24 Jan 2018
Placebo
(Placebo)
igkqwceltd(qwozjsesyt) = kvkgxxdbmv lormajyjrb (smwexbfxmb, jyhefdarpn - uwtljqnnak)
Not Applicable
-
(kgxqarrrcz) = oyodzqrump jlgyloajcz (oawiedyuwb )
-
17 Oct 2016
Phase 3
104
(Citicoline)
uarbqdptwe(fofmenokcc) = yirxliinls nhpejulrqg (cwapwpgolb, xrjywsadua - gebamyapeb)
-
11 Feb 2015
Placebo
(Placebo)
uarbqdptwe(fofmenokcc) = wqvjnlfnjh nhpejulrqg (cwapwpgolb, oqbntreubd - pipdkyqpcx)
Phase 2
21
placebo
(Placebo)
qyxonjhmrp(szroamnxjw) = wglhcuewoz hcuhrdopjx (twitnipssj, qsharebbqj - fzhlndprlh)
-
22 Oct 2014
(Citicoline)
qyxonjhmrp(szroamnxjw) = yjlfsuyuro hcuhrdopjx (twitnipssj, qtlpscuxko - fwgztewoew)
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Core Patent

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Approval

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Regulation

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