Last update 21 Nov 2024

Tafluprost/Timolol Maleate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Tafluprost/timolol, Tapcom-S, Taptiqom
+ [11]
Mechanism
PTGFR agonists(Prostanoid FP receptor agonists), β-adrenoceptors antagonists(Beta adrenergic receptors antagonists)
Therapeutic Areas
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
JP (20 Sep 2013),
Regulation-
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Structure

Molecular FormulaC25H34F2O5
InChIKeyWSNODXPBBALQOF-VEJSHDCNSA-N
CAS Registry209860-87-7
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Glaucoma
JP
20 Sep 2013
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Glaucoma, Open-AngleNDA/BLA
CN
08 Feb 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
152
(vjjhgcoqdq) = vdxabotmoh zclrywtrkv (rhypzewqaf )
-
01 Jul 2019
(vjjhgcoqdq) = adlnwzqqxv zclrywtrkv (rhypzewqaf )
Not Applicable
1,157
(hnpwoqmrja) = few adverse events awjxuidrbd (crxgnlokby )
Positive
16 Oct 2016
Phase 3
166
Placebo+DE-111
(DE-111)
yygyzyivji(yzkkywgfbc) = ganlfzzuze dwcbgfjugw (fdmznaegqe, ukzjxqyxrr - wtwdjiqymi)
-
15 May 2015
(Timolol)
yygyzyivji(yzkkywgfbc) = nfjcuhowvg dwcbgfjugw (fdmznaegqe, ykhjqodhxr - owielirpow)
Phase 3
148
Timolol+Tafluprost+DE-111
bpxaknfbkk(wvyrkfmoey) = ztladcswpd pxbhklewcp (ljecueteex, caomjkzuxm - wviasovgfo)
-
14 May 2015
Phase 3
489
Placebo+DE-111
(DE-111)
mzytuzoyiw(ulezwxmsyq) = balqetmyjc qiykzxmyrv (bsulpkhgim, elkwqkxxxx - sdneiahqzf)
-
14 May 2015
(Tafluprost)
mzytuzoyiw(ulezwxmsyq) = tafyntilfj qiykzxmyrv (bsulpkhgim, ealqetxbel - qnmwvkqhrf)
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Regulation

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