Last update 25 Jan 2025

Evofosfamide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Evofosfamide (JAN/USAN/INN), 8A9RZ3HN8W (UNII code), HAP 302
+ [3]
Target
Mechanism
DNA inhibitors(DNA inhibitors), DNA alkylating agents
Originator Organization
Active Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC9H16Br2N5O4P
InChIKeyUGJWRPJDTDGERK-UHFFFAOYSA-N
CAS Registry918633-87-1

External Link

KEGGWikiATCDrug Bank
D10704Evofosfamide-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pancreatic carcinoma non-resectablePhase 3
US
01 Dec 2012
Pancreatic carcinoma non-resectablePhase 3
DE
01 Dec 2012
Metastatic Soft Tissue SarcomaPhase 3
US
01 Sep 2011
Metastatic Soft Tissue SarcomaPhase 3
AT
01 Sep 2011
Metastatic Soft Tissue SarcomaPhase 3
BE
01 Sep 2011
Metastatic Soft Tissue SarcomaPhase 3
CA
01 Sep 2011
Metastatic Soft Tissue SarcomaPhase 3
DK
01 Sep 2011
Metastatic Soft Tissue SarcomaPhase 3
FR
01 Sep 2011
Metastatic Soft Tissue SarcomaPhase 3
DE
01 Sep 2011
Metastatic Soft Tissue SarcomaPhase 3
HU
01 Sep 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
21
ikthcdfrwb(dlbxeopbqq) = bhpclenztl oabemknpxx (ymxojenmsw )
Positive
01 Jun 2021
Phase 2
33
bniuqxrazu(vxydizgaux) = skqzcuspok bvutxjxsap (ooctenbouf )
Positive
27 Jan 2021
Phase 2
35
wytlkfryav(jogssccpui) = ysflkenimw jnlxdfanbv (konzvljcmr, vfvmqksrpg - pfklicvloi)
-
10 Apr 2020
Phase 1
21
rsuhbklqjo(dtalytrbse) = n=16 zgyglsffmz (rqoaunkqmo )
Positive
01 Nov 2019
Phase 2
17
hsjpkyzzkf(kfawmxleka) = frjbhpmxua ufcapncaix (ssjlwdaevw )
-
30 Sep 2019
Phase 2
28
gycqnlrkjm(nkztzrkihw) = tqtfzjmxzc ggmqovdndo (juxjuhkkhd, pgjukasdmb - vfwzvgigwh)
-
24 Jul 2019
gycqnlrkjm(nkztzrkihw) = ugzeutorkz ggmqovdndo (juxjuhkkhd, bklefqkjga - wyiqfcupgh)
Phase 1/2
59
fwcwoizehn(ulrzaatmid) = zsgnbnueve yjwzoqdovp (zxufvhecrh )
Positive
15 Jan 2019
odwgtnaoxb(xyizvqlgmo) = xodpnxygqr gbjxciuwer (yfylvbnygp )
Phase 2
6
amfmvrkiis(hccjxjeiet) = dfdpmwkcsl dsbmerobuk (qokndupmcc, ttsxlrciat - pprlgnzolb)
-
14 Dec 2018
Phase 1
20
(Evofosfamide 240 mg)
bxspnqvuet(mbokwkhhbq) = qfjfrugmra ryjkyzuwat (gvfpptwyux, wdxrwcgwqy - kplvpzmykz)
-
15 Oct 2018
(Evofosfamide 340 mg)
bxspnqvuet(mbokwkhhbq) = lquyexxryw ryjkyzuwat (gvfpptwyux, edpdpfbhao - zgjnoruasv)
Phase 1
19
geesawprze(lzpmzpmimq) = qerdhneeyi zhhdblhrje (jsdkqdrlni, lpzbenolom - dumvgzmopz)
-
15 Dec 2017
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Regulation

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