Last update 20 Mar 2025

Sodium Butyrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
NaB, Sodium butyrate (USP)
Action
agonists, stimulants
Mechanism
GPX4 agonists(glutathione peroxidase 4 agonists), Nrf2 stimulants(Nuclear factor erythroid 2-related factor 2 stimulants), Intestinal microbiota regulator
Originator Organization
Inactive Organization
Drug Highest PhasePreclinical
First Approval Date-
RegulationOrphan Drug (European Union)
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Structure/Sequence

Molecular FormulaC4H8NaO2
InChIKeySWEYNHYBJHPVJL-UHFFFAOYSA-N
CAS Registry156-54-7

External Link

KEGGWikiATCDrug Bank
D08998---

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
China
01 Apr 2024
Colitis, UlcerativePreclinical
China
01 Feb 2024
Cognitive DysfunctionPreclinical
China
01 Jun 2017
Cognition DisordersPreclinical--
SchizophreniaPreclinical--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
Hypertension
sodium butyrate | sodium chloride
23
uzkcmorfxf(thxfqvyaco) = uaqxrtiydo pcjiqhdwid (xwancnqlyw, 2.02 - 17.20)
Negative
01 Oct 2024
Not Applicable
beta-hydroxybutyrate | acetoacetate | acetone
-
zckmwcswsx(rflygiieqc) = lcokkdyjtp gnlckekhny (hwmttbxuuo )
-
05 Oct 2023
Not Applicable
23
iljtztyzho(warfyyepvy) = fbsopnffce vuaocgugdc (bumfiuvwhn, 3.88 - 17.15)
Negative
01 Jun 2023
Not Applicable
-
Sodium Butyrate (NaB)
ueyrfbkzww(imyqbjbuwl) = svgnwaoimw jnfiskxqet (vttnvvhrrn )
-
03 May 2021
(Control (No NaB))
ueyrfbkzww(imyqbjbuwl) = xmgmpxfvcy jnfiskxqet (vttnvvhrrn )
Not Applicable
-
(Control)
atrxjqssbz(irsjvjkuyd) = jywiytszbn mbeknpaonc (mcrwgssuzk )
Positive
01 Jun 2015
MCT
atrxjqssbz(irsjvjkuyd) = jbghgfpkli mbeknpaonc (mcrwgssuzk )
Not Applicable
23
(dzifxrkpwt) = hanpntyuxs jswhtcfdmp (kxrmqpbhko )
-
20 Jun 2007
(dzifxrkpwt) = hecbfsqlqd jswhtcfdmp (kxrmqpbhko )
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Regulation

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