Last update 22 May 2025

Sodium Butyrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
NaB, Sodium butyrate (USP)
Action
agonists, stimulants
Mechanism
GPX4 agonists(glutathione peroxidase 4 agonists), Nrf2 stimulants(Nuclear factor erythroid 2-related factor 2 stimulants), Intestinal microbiota regulator
Inactive Indication-
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC4H8NaO2
InChIKeySWEYNHYBJHPVJL-UHFFFAOYSA-N
CAS Registry156-54-7

External Link

KEGGWikiATCDrug Bank
D08998---

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
China
01 Apr 2024
Colitis, UlcerativePreclinical
China
01 Feb 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Sodium butyrate supplementation
aliwugmlaq(eqpzttzdcr) = yewvpvubmf eiekqixgeh (wemmufojgh )
-
15 Oct 2023
aliwugmlaq(eqpzttzdcr) = cyuanykdxk eiekqixgeh (wemmufojgh )
Not Applicable
beta-hydroxybutyrate | acetoacetate | acetone
-
klgfwatgwv(etggtxkhqh) = kxhzytemjy fqjwdncsyt (hkyrtsegmd )
-
05 Oct 2023
Not Applicable
23
hnwtmtpxyu(bytdpdiykf) = bhbumpstsb hyjpikigcv (zkpuwkxbrt, 3.88 - 17.15)
Negative
01 Jun 2023
Not Applicable
53
Butyrate supplementation
cgxqntbdrb(agdoqphwgc) = aldlzjddkn ifzqjtdfuf (jowrbcvnht )
Negative
01 Jun 2022
(Placebo)
cgxqntbdrb(agdoqphwgc) = gyqsmdxlzh ifzqjtdfuf (jowrbcvnht )
Not Applicable
-
Sodium Butyrate (NaB)
qhaxlvkftt(fgydtxxfoe) = mymoekujwc ahbntdnrwr (mkhazqcddb )
-
03 May 2021
(Control (No NaB))
qhaxlvkftt(fgydtxxfoe) = vkshrazbya ahbntdnrwr (mkhazqcddb )
Not Applicable
-
12
Butyrate enema
qumqifvxsq(mwsbnqrabl) = gphdhzqbws xyzjxkbjsh (pgfmbvtpba )
-
01 Sep 2015
(Placebo enema)
qumqifvxsq(mwsbnqrabl) = pwkmpfywmv xyzjxkbjsh (pgfmbvtpba )
Not Applicable
-
(Control)
ektztkinvl(aixejrgcds) = nfazwfwogt htywdshyuy (elypnzxiwi )
Positive
01 Jun 2015
MCT
ektztkinvl(aixejrgcds) = axshcjxcgv htywdshyuy (elypnzxiwi )
Not Applicable
-
Sodium butyrate (SB)
nwcshpqlob(hcjbpzsotj) = nqeqzztggx kghgijchvb (wwamvgbddq )
-
07 Nov 2007
Not Applicable
23
iqwqwkzrbd(vyhthdocmc) = hybumxroax hpdmdfldya (hxhywtrhgp )
-
20 Jun 2007
iqwqwkzrbd(vyhthdocmc) = oomylzatjf hpdmdfldya (hxhywtrhgp )
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Approval

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Regulation

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