Last update 21 Nov 2024

SEL-110

Overview

Basic Info

Drug Type
Gene therapy
Synonyms
ImmTOR, SVP Rapamycin, SVP-R
+ [3]
Mechanism
MUT stimulants(Methylmalonyl-CoA Mutase stimulants), mTOR inhibitors(Serine/threonine-protein kinase mTOR inhibitors)
Therapeutic Areas
Active Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
MesotheliomaPhase 2--
GoutDiscovery
US
10 Sep 2020
Methylmalonic AcidemiaDiscovery
US
-
Urea Cycle Disorders, InbornDiscovery
US
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
60
SEL-212 (0.4mg/kg pegsiticase + 0.08mg/kg SVP-R)
lwdubxneds(kbdsyohgqe) = Of 7 observed serious infusion reactions, 4 were associated with patients receiving pegsiticase alone or the lowest dose of SEL-212, as expected, and two were related to dosing errors lbvcvqlsiz (eplnuberzz )
Positive
07 Nov 2017
Pegsiticase alone (0.4mg/kg)
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Regulation

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