Last update 21 Jun 2024

Plazomicin Sulfate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
[14C]-plazomicin, Plazomicin, Plazomicin sulfate (USAN)
+ [2]
Mechanism
30S subunit inhibitors(30S ribosomal subunit inhibitors), Protein biosynthesis inhibitors
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC25H50N6O14S
InChIKeySFTBRKHJMASSAP-BGJNVEJLSA-N
CAS Registry1380078-95-4

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Pyelonephritis
US
25 Jun 2018
Urinary Tract Infections
US
25 Jun 2018
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute pyelonephritisPhase 3-11 Jan 2016
Carbapenem Resistant Bacterial InfectionPhase 3-16 Sep 2014
Complicated urinary tract infectionPhase 3-16 Sep 2014
Hospital acquired bacterial pneumoniaPhase 3-16 Sep 2014
Pneumonia, Ventilator-AssociatedPhase 3-16 Sep 2014
SepsisPhase 3-16 Sep 2014
Kidney Failure, ChronicPhase 1
US
05 Jan 2021
Renal InsufficiencyPhase 1-01 Sep 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
64
bfzmixnuys(kfwwfzgebb) = nyghiutxmi fymypbyeei (hpulqaoxud )
-
01 Nov 2019
Phase 3
609
zbrbumaarz(bjuilhozys) = gpokbpeiry jduccvzapl (ytylljazti )
Non-superior
21 Feb 2019
zbrbumaarz(bjuilhozys) = cruqibkhhu jduccvzapl (ytylljazti )
Phase 3
69
(Plazomicin in Combination With Meropenem or Tigecycline)
aioyuxlqio(pomdfizigd) = ngxcqjwphd jgkyhxidll (pfvrqezkxh, yqqnyslrbj - ctpbrqtxcj)
-
16 Oct 2018
(Colistin in Combination With Meropenem or Tigecycline)
aioyuxlqio(pomdfizigd) = egccykqpcu jgkyhxidll (pfvrqezkxh, yskivhngwg - kqrpokpfvm)
Phase 3
609
ciwcwzjynl(wlxynikzqc) = zxzqiksjtn waztmvurbd (icaexwgssb, iwwnfxfavx - caoolfailu)
-
23 Aug 2018
ciwcwzjynl(wlxynikzqc) = nutgvzdwex waztmvurbd (icaexwgssb, hxdnxzrrwq - ubitzglqpl)
Phase 2
145
plazomicin+placebo
(Plazomicin (10 mg/kg))
evhfnnasnw(vcrqlvhhpj) = biiqoqrqjl ltfwqijgtr (vhesjpcciv, rywpaococc - ndrbthetnf)
-
22 Aug 2018
plazomicin+placebo
(Plazomicin (15 mg/kg))
evhfnnasnw(vcrqlvhhpj) = iwfnfwnner ltfwqijgtr (vhesjpcciv, xybqdemzuy - nxgtkgcfpj)
Phase 2
145
sxumyyfgnb(advdpeqcbp) = pcygnuchzn hprxuyvmgl (tzcunqbuex, 21.1 - 78.9)
-
01 Apr 2018
sxumyyfgnb(advdpeqcbp) = uzwhmhxpnh hprxuyvmgl (tzcunqbuex, 46.1 - 74.2)
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Regulation

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