Delving into the Latest Updates on Shanghai New Asiatic Pharmaceuticals Co., Ltd. with Synapse

Overview

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Other Diseases

Infectious Diseases

Nervous System Diseases

Small molecule drug

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

Disease Domain	Count

Nervous System Diseases	3
Infectious Diseases	3
Immune System Diseases	1

Top 5 Drug Type	Count

Small molecule drug	9

Top 5 Target	Count

PBPs(Bacterial penicillin-binding protein)	3
GABAA receptor(Gamma-aminobutyric acid A receptor)	2
AHR(Aryl hydrocarbon receptor)	1
Opioid receptors	1

DDM product as additive for several imported PMMA units is not produced in China, mainly depends on import.In this paper, a new synthesis process of DDM, alkyl sodium sulfate method, was introduced, and the factors affecting the yield were researched.Exptl. results show that, the process is effective, less investment, low cost, obvious economic benefit.Single pass yield exceeds 90%, reaches French patent level; the quality of product fully reaches quality standards

Liaoning Huagong

Study on industrialization process of thiotriazinone

Author: Yu, Yonghong ; Lin, Lin

In order to improve the product quality and yield by finding out the optimal technol. conditions, thiotriazinone sodium was synthesized by condensation of 2-methyl-3-thiosemicarbazide, di-Et oxalate and sodium methoxide in a mixed solvent (a polar proton solvent and a polar non-proton solvent) at 0∼45°C, and then the target product thiotriazinone (TTZ) was obtained by hydrochloric acid acidification.By using mixed solvents, the viscosity of the synthesized process system was greatly improved, the yield of thiotriazinone (TTZ) was increased to more than 90% (calculated by 2-methyl-3-thiosemicarbazide), and the average purity was over 99.5%, the byproduct material, 1-methyl-5-mercapto-1,2,4-triazole-3-carboxylate (TTA), was less than 0.1%.So, this industrial method is suitable for the synthesis of thiotriazinone (TTZ).

Jingxi Shiyou Huagong Jinzhan

Fe/ZnO photocatalytic degradation of methylene blue

Author: Zhang, Yi

Fe/ZnO photocatalyst was prepared by impregnation method with Fe (NO₃)₃·9 H₂O and ZnO as raw materials.And the catalytic degradation performance of Fe/ZnO photocatalyst on methylene blue was investigated.The effects of catalyst dosage, initial concentration of methylene blue solution, reaction time, light source, and light power on the catalytic degradation of methylene blue were explored in details.Results showed that the degradation rate of methylene blue could reach 88% under the conditions of catalyst dosage of 0.2 g, 20 mL methylene blue solution of 10 mg/L, xenon lamp used as the light source with 1000 W for reacting 3 h.When using mercury lamp power as the light source with 400 W for reacting 40 min, the degradation rate of methylene blue was close to 100%.

100 Deals associated with Shanghai New Asiatic Pharmaceuticals Co., Ltd.

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100 Translational Medicine associated with Shanghai New Asiatic Pharmaceuticals Co., Ltd.

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Pipeline

Pipeline Snapshot as of 26 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Phase 2 Clinical

1

Phase 3 Clinical

NDA/BLA

1

6

Approved

Other

2

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Current Projects

Drug(Targets)	Indications	Global Highest Phase

Carbenicillin Disodium ( PBPs )	Pseudomonas Infections More	Approved
Cefamandole Nafate ( PBPs )	Bacterial Infections More	Approved
Pentobarbital Sodium ( GABAA receptor )	Sleep Initiation and Maintenance Disorders More	Approved
Amobarbital sodium ( GABAA receptor )	Sedation More	Approved
Loperamide Hydrochloride ( Opioid receptors )	Diarrhea More	Approved