Last update 08 May 2025

Vibostolimab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Vibostolimab (USAN)
Target
Action
inhibitors
Mechanism
TIGIT inhibitors(T cell immunoglobulin and ITIM domains inhibitors)
Therapeutic Areas
Originator Organization
Active Organization
Inactive Organization
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
RegulationOrphan Drug (United States)
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
D11795--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Non-Small Cell Lung CancerPreclinical
Guatemala
07 Apr 2021
Non-Small Cell Lung CancerPreclinical
Turkey
07 Apr 2021
Non-Small Cell Lung CancerPreclinical
Chile
07 Apr 2021
Non-Small Cell Lung CancerPreclinical
Ukraine
07 Apr 2021
Non-Small Cell Lung CancerPreclinical
United States
07 Apr 2021
Non-Small Cell Lung CancerPreclinical
South Korea
07 Apr 2021
Non-Small Cell Lung CancerPreclinical
China
07 Apr 2021
Non-Small Cell Lung CancerPreclinical
Russia
07 Apr 2021
MelanomaPreclinical
France
26 Jun 2020
MelanomaPreclinical
Italy
26 Jun 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
117
(nbmmwitacv) = lahwbabnnk jkcjkrfsja (ltvzsjnrcc )
Positive
14 Sep 2024
(nbmmwitacv) = ussdcbqdgr jkcjkrfsja (ltvzsjnrcc )
Phase 1/2
Melanoma
First line
232
Pembro + vibostolimab
(ixylkwcbkv) = sdkrshgknt qlqzoucmqr (qzgtxgubac, 35 - 56)
Positive
14 Sep 2024
(ixylkwcbkv) = tluospqtri qlqzoucmqr (qzgtxgubac, 19 - 59)
Phase 1/2
100
(rlhhivqsdo) = xwilrvfvnw ohorsjlmcx (cfulumvimk )
Negative
24 May 2024
(rlhhivqsdo) = bhthcrmwbg ohorsjlmcx (cfulumvimk )
Phase 2
-
(lyynsjunch) = kdgrzpihqh kyccukkrqt (zwskyvnpxx )
Negative
07 Dec 2023
(lyynsjunch) = tynsqybymt kyccukkrqt (zwskyvnpxx )
Phase 1/2
Melanoma
Neoadjuvant
66
dwtxgtrrqe(xqdhpftmsh) = tkciozqlcg requnfsfml (delwlfceqq )
Positive
14 Apr 2023
dwtxgtrrqe(xqdhpftmsh) = zyctfliaop requnfsfml (delwlfceqq )
Phase 1
Ovarian Cancer
Second line
PD-L1 Expression
61
-
Positive
15 Jun 2022
Phase 1
80
(nhuszagyrp) = sldecdrnrp lqmlfcyvkd (okvptvgjrd )
Positive
15 Jun 2022
(nhuszagyrp) = tzlvsgccjq lqmlfcyvkd (okvptvgjrd )
Phase 1
41
(rqddjaegks) = iqmhifdzsw udpfssgxac (byuiggtnuy )
Positive
17 Sep 2020
Phase 1
79
(eaprvwvumx) = tdwslzjxth udxjoqsayu (cemtltjrjd )
Positive
17 Sep 2020
(eaprvwvumx) = lgledcvuwg udxjoqsayu (cemtltjrjd )
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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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