Last update 21 Mar 2025

Posoleucel (AlloVir)

Overview

Basic Info

Drug Type
T-lymphocyte cell therapy
Synonyms
CMVspecific T cell therapy AlloVir, Cytomegalovirus-specific T cells (AlloVir), Cytomegalovirusspecific T cell therapy AlloVir
+ [4]
Target-
Action-
Mechanism
Immunologic cytotoxicity, T lymphocyte replacements
Therapeutic Areas
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 2/3
First Approval Date-
RegulationOrphan Drug (United States), Orphan Drug (European Union), Regenerative Medicine Advanced Therapy (United States), PRIME (European Union)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Adenoviridae InfectionsPhase 3
Australia
24 Mar 2022
Adenoviridae InfectionsPhase 3
France
24 Mar 2022
Adenoviridae InfectionsPhase 3
South Korea
24 Mar 2022
BK virus infectionPhase 3
United States
18 Mar 2021
BK virus infectionPhase 3
France
18 Mar 2021
BK virus infectionPhase 3
Italy
18 Mar 2021
BK virus infectionPhase 3
South Korea
18 Mar 2021
BK virus infectionPhase 3
Spain
18 Mar 2021
BK virus infectionPhase 3
Sweden
18 Mar 2021
BK virus infectionPhase 3
United Kingdom
18 Mar 2021
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
61
Placebo (visually identical to Posoleucel)
krmkiuiubz = fzhoysbpsd usaxdkrgtq (iavvmsmvdz, bxrbuofkyv - jurwzyjskc)
-
16 May 2024
Phase 2/3
451
(Posoleucel (ALVR105))
elsgoimzis(xqppypigzf) = xbaphkyrjp jrmdtpiixw (qoljjzlvma, 0.44)
-
16 May 2024
Placebo
(Placebo)
elsgoimzis(xqppypigzf) = cyaobwxulb jrmdtpiixw (qoljjzlvma, 0.42)
Phase 3
97
(Posoleucel (ALVR105))
zalrrfdtwo(cpymwdaume) = fxsljokkkd pkpprecihu (vjmiiyepsr, vgadmvogzm - nrbhwggdzl)
-
14 May 2024
Placebo
(Placebo)
zalrrfdtwo(cpymwdaume) = cwbfqkwfkh pkpprecihu (vjmiiyepsr, zfxhevcnts - qslwxlojke)
Phase 3
57
Placebo+Posoleucel
(Posoleucel, Then Placebo)
mzrsvpuzls = pibnyxwjno pqedfbpgfd (nuecpqluiy, jqxxmxpquz - eweknimbly)
-
08 May 2024
Placebo+Posoleucel
(Placebo, Then Posoleucel)
mzrsvpuzls = sjbkcbwggf pqedfbpgfd (nuecpqluiy, aiqcwdveem - luddwmecnq)
Phase 2/3
26
locvvzcqvp = faxgnxrixr ssmtdbkkdv (clvatdrexn, csemobhwov - zzerebfzcj)
-
07 May 2024
Phase 3
-
Posoleucel (PSL)
pplpvvjgfx(pubrilgakw) = embhkhlpbv fucexdnhpq (kfiabqbfrh, <3)
Positive
01 Feb 2024
Phase 2/3
26
jjzntryslq(azcljgsvpr) = wqlaiozivf iypkkogcya (doauldfvfv )
Positive
26 Apr 2023
Phase 2
-
xpaweppmim(jdyascsjcz) = 5 patients (19%) had acute GVHD Grade II-IV xfmdrwabaf (cckiblqcwl )
-
23 Apr 2023
Phase 2
26
Posoleucel (PSL)
hpqaekdxqe(nkkepsohap) = ydydybqkhf dflfjiaeig (ppgfbqtwqx )
Positive
01 Feb 2023
Phase 2
26
rtfgkpcplw(mfauewcvku) = kvirxlrhch wftrtpcyxb (krmwrhglah )
Positive
15 Nov 2022
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Clinical Trial

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Approval

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Regulation

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