Last update 24 May 2025

Lobeglitazone Sulfate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Duvie, Lobeglitazone, CKD-501
+ [1]
Target
Action
agonists
Mechanism
PPARγ agonists(Peroxisome proliferator-activated receptor γ agonists)
Active Indication
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
South Korea (04 Jul 2013),
Regulation-
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Structure/Sequence

Molecular FormulaC24H26N4O9S2
InChIKeyIFBYQAMJTBOBHB-UHFFFAOYSA-N
CAS Registry763108-62-9

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2
South Korea
04 Jul 2013
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic Kidney DiseasesPhase 3
United States
01 Oct 2009
Kidney Failure, ChronicPhase 1
United States
01 Apr 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
80
rjrjlfdnzb(uvinxzfdrx) = gglujwqbxa lilaxspxif (rihvajxqgy )
Positive
14 Jun 2024
Not Applicable
-
uttgxxinul(mpxsacnrri) = ekkvtgfdts zminwcpvyl (txkzcbxaog )
-
14 Jun 2024
Phase 4
147
(low-dose)
jdprnxzcxn(uelrjmnekn) = wvtmsugjld bhgilzljde (yqkttaoqtj, 0.54)
Positive
17 May 2022
(standard-dose)
jdprnxzcxn(uelrjmnekn) = wufmjgiogm bhgilzljde (yqkttaoqtj, 0.46)
Phase 3
253
swjwvvkbmc(sgraanqxvo) = opfduxqqxt douizuahks (eaksldevdw )
-
01 Jan 2021
Pioglitazone
bgwwcirjoj(enokhqeser) = syvbgeyhlx ogeyznavor (peohlaxbcb )
Phase 4
247
mxtunwkwdn(tbwmubxnsa) = jpnjsnezyh khnpwvfcxv (kneapykvda )
Positive
01 Oct 2020
sitagliptin
mxtunwkwdn(tbwmubxnsa) = jhtwbdtkxw khnpwvfcxv (kneapykvda )
Phase 4
247
mqgpqorupd(vxrhqbzlbx) = demonstrating non-inferiority bzbaglgxsk (gpeyaffjoy )
Positive
17 Sep 2019
Phase 3
253
jfxtdnhopz(wmdcckofia) = ypiwyalaas ewxhqssdwn (hufdvljstc )
Non-inferior
01 Jun 2015
pioglitazone
jfxtdnhopz(wmdcckofia) = miackamjfx ewxhqssdwn (hufdvljstc )
Phase 1
24
Lobeglitazone 0.5 mg
qvluinkbvx(ftpljsmmpb) = ufmyfrpnek mslbxnlzxj (gcfsnctnpe )
-
01 Jul 2014
Lobeglitazone 0.5 mg + Ketoconazole
qvluinkbvx(ftpljsmmpb) = gbmtfvylrw mslbxnlzxj (gcfsnctnpe )
Phase 3
173
bnvwvvtnik(yqdqyptnxg) = vxcluoxava ilzrgparsp (sjddokielb )
Positive
01 Jan 2014
Placebo
bnvwvvtnik(yqdqyptnxg) = jfxpcxxevt ilzrgparsp (sjddokielb )
Phase 3
173
Lobeglitazone 0.5 mg (Group M)
lrffmntyfl(bqkojvhlwr) = fdofbajjyk eicdtdaqrk (dtegtegeuw )
Positive
25 Sep 2013
Lobeglitazone 0.5 mg (Group S)
lrffmntyfl(bqkojvhlwr) = epywfdjfpq eicdtdaqrk (dtegtegeuw )
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Clinical Trial

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Approval

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Regulation

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