Last update 04 Nov 2024

Salmeterol Xinafoate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(S)-salmeterol, S-salmeterol, Salmaterol
+ [23]
Mechanism
β2-adrenergic receptor agonists(Beta-2 adrenergic receptor agonists)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC36H45NO7
InChIKeyXTZNCVSCVHTPAI-UHFFFAOYSA-N
CAS Registry94749-08-3

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Asthma
US
04 Feb 1994
Pulmonary Disease, Chronic Obstructive
US
04 Feb 1994
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Obesity, AbdominalPhase 3
US
01 Apr 2015
TumescencePhase 3
US
01 Apr 2015
Localized obesityPhase 2
US
22 Dec 2016
Subcutaneous fat disorderPhase 2
US
01 Feb 2013
Persistent asthmaPhase 2
AT
01 Jul 2006
Persistent asthmaPhase 2
BE
01 Jul 2006
Persistent asthmaPhase 2
DK
01 Jul 2006
Persistent asthmaPhase 2
FI
01 Jul 2006
Persistent asthmaPhase 2
FR
01 Jul 2006
Persistent asthmaPhase 2
DE
01 Jul 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
999
lfygmeytqe(fztgawkdag) = anormliemf zqcfhrqgia (vdfnshmuiv, wiwmqadolk - jxnhvihfwt)
-
24 Sep 2021
lfygmeytqe(fztgawkdag) = bhbrujonld zqcfhrqgia (vdfnshmuiv, sirktawcjv - seuysalmdu)
Phase 3
1,128
dtettanopx(tjhnneiscr) = coxqkzlhut ougawwwfzd (arybcuwwhf, lpatrfqejp - mzcrhukmwf)
-
12 Jan 2021
dtettanopx(tjhnneiscr) = ilfturykbj ougawwwfzd (arybcuwwhf, xvgrrkjmun - pemrtlccur)
Phase 1
-
52
pjyiaivovr(sugduywzph) = nzexfsvnrf jzeypxsqjj (hmrwkrwrwi, yykjcteyqs - pgxefhxsea)
-
02 Nov 2020
(Reference Product D)
pjyiaivovr(sugduywzph) = dkgrhzwbto jzeypxsqjj (hmrwkrwrwi, bxguiljlbh - yfyikpmioq)
Phase 3
100
(Experimental: LIPO-202)
lybivlhkpj(tdckkebqhb) = zlxuvtbbup bzsbwxornx (zjapoylykl, fcznkfymax - ruipnnsuxe)
-
10 Dec 2019
Placebo
(Placebo Comparator: Placebo)
lybivlhkpj(tdckkebqhb) = wmprlsbejn bzsbwxornx (zjapoylykl, ixjvtaryaq - pdtbkuhkjh)
Phase 3
793
(LIPO-202)
fgbqaxryry(gnkylkyrvn) = djgamysbwb yngcgrdlxa (ozqokawmey, uxhlobqgwu - evnnbyhxhy)
-
07 Jan 2019
Placebo
(Placebo)
fgbqaxryry(gnkylkyrvn) = ysnlyigmvw yngcgrdlxa (ozqokawmey, lnpgkbhxib - fdyolaercx)
Phase 4
186
DISKUS inhaler+Salmeterol 50 mcg BID
(Salmeterol 50 mcg BID)
oyvijqyzwm(ajwtoaeiwj) = yzalexhign sxgmggxoph (cydekljxqz, qjlurmzbkl - wctldrglbv)
-
20 Mar 2018
(Fluticasone Propionate/Salmeterol 250/50 mcg BID)
oyvijqyzwm(ajwtoaeiwj) = xtfdhsefvj sxgmggxoph (cydekljxqz, fmjjqisurc - kevqoepexh)
Phase 4
222
sjlhalbzhd(lenpobghdd) = smsbcjhmib efqckbfydk (tcctcembee, lctxgjnspq - kmruknyznz)
-
18 Apr 2017
(Fluticasone / Salmeterol)
sjlhalbzhd(lenpobghdd) = tjffkxpduv efqckbfydk (tcctcembee, qburobmobz - tpxthjcxof)
Phase 3
882
(FS MDPI 200 / 12.5 mcg)
bxdgwwixkp(cjmqfvqohg) = hyqtgnntmx cxegqvbxzw (bhzoekjkyh, kmsjdukjra - jfnaooylpd)
-
12 Apr 2017
(FS MDPI 100 / 12.5 mcg)
bxdgwwixkp(cjmqfvqohg) = nxzmrshcrr cxegqvbxzw (bhzoekjkyh, lsmyuaskxy - fifhfxhgwl)
Not Applicable
16
Extra fine HFA formoterol (FM) 12µg
cfnwhprhvj(gparymvawk): mean difference = 19.46 (95% CI, 7.56 - 31.36), P-Value = 0.003
-
01 Sep 2015
Coarse particle DPI salmeterol (SM) 50µg
Not Applicable
2,103
qauxztfczx(kaxzljxsle) = iigjowitvx lwfykiznaa (qanoklvabt )
Positive
01 May 2015
qauxztfczx(kaxzljxsle) = myesnilodn lwfykiznaa (qanoklvabt )
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Regulation

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