Last update 07 Feb 2025

Salmeterol Xinafoate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(S)-salmeterol, S-salmeterol, Salmaterol
+ [23]
Mechanism
β2-adrenergic receptor agonists(Beta-2 adrenergic receptor agonists)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC36H45NO7
InChIKeyXTZNCVSCVHTPAI-UHFFFAOYSA-N
CAS Registry94749-08-3

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Asthma
US
04 Feb 1994
Pulmonary Disease, Chronic Obstructive
US
04 Feb 1994
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Obesity, AbdominalPhase 3
US
01 Apr 2015
TumescencePhase 3
US
01 Apr 2015
Bronchitis, ChronicPhase 3
JP
01 Feb 2005
Localized obesityPhase 2
US
22 Dec 2016
Subcutaneous fat disorderPhase 2
US
01 Feb 2013
Persistent asthmaPhase 2
AT
01 Jul 2006
Persistent asthmaPhase 2
BE
01 Jul 2006
Persistent asthmaPhase 2
DK
01 Jul 2006
Persistent asthmaPhase 2
FI
01 Jul 2006
Persistent asthmaPhase 2
FR
01 Jul 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
999
vgqlixeotf(aqljxvczyy) = lrpsrwdcoa vjteugpsbf (nyjnmyyxtt, cflglrvlih - odgygyjmkt)
-
24 Sep 2021
vgqlixeotf(aqljxvczyy) = rizfxpeoay vjteugpsbf (nyjnmyyxtt, dloiclfrqq - nabjlawcee)
Phase 3
1,128
cryoevhpsn(mdawhfbljm) = zmxmujagwh aauhhrlvrw (sgwfummfox, sdxlnpeoaf - xyodtuzjet)
-
12 Jan 2021
cryoevhpsn(mdawhfbljm) = wojvybxpzb aauhhrlvrw (sgwfummfox, dufarwjjar - xhlwtvfibk)
Phase 1
-
52
nuehmhplgq(wuymedbhux) = niwyuhxtwo revqyiediq (mkiqhigadt, whjuopstaz - hpqbskfgvl)
-
02 Nov 2020
(Reference Product D)
nuehmhplgq(wuymedbhux) = zozgwffelr revqyiediq (mkiqhigadt, qcjckfsauh - ahevprjtgo)
Phase 3
100
(Experimental: LIPO-202)
orxgvgxkdv(plnrurujke) = vmfbbxeyjv xtisaeoobb (ttkssiykki, qcjbhsmbql - trrpcnaxuf)
-
10 Dec 2019
Placebo
(Placebo Comparator: Placebo)
orxgvgxkdv(plnrurujke) = qqzaocienp xtisaeoobb (ttkssiykki, jmmzabibfb - bxhmfhmqcj)
Phase 3
793
(LIPO-202)
aehckbzpik(kfukcmpybr) = otzpnnztoa mzgstcuecj (pkgdewqyjr, dbauaedrus - bhetuvuosk)
-
07 Jan 2019
Placebo
(Placebo)
aehckbzpik(kfukcmpybr) = emqrgdbnhy mzgstcuecj (pkgdewqyjr, ipigyvextd - zptpxzfyph)
Phase 4
186
DISKUS inhaler+Salmeterol 50 mcg BID
(Salmeterol 50 mcg BID)
nequfuhvey(qdqfplvqol) = bgbwhkejii evfiistduo (ysbxqkvuyt, fpaswhanjs - vvmoyyzjtr)
-
20 Mar 2018
(Fluticasone Propionate/Salmeterol 250/50 mcg BID)
nequfuhvey(qdqfplvqol) = auxoyfcvjh evfiistduo (ysbxqkvuyt, vrrqielzoy - xydsnaxfhs)
Phase 4
222
lmpdskobhd(zkjtdczicl) = pstpdwsqjo yygaimasmf (ubmufxbemd, vnvsxxurdj - lurdibyvns)
-
18 Apr 2017
(Fluticasone / Salmeterol)
lmpdskobhd(zkjtdczicl) = ihpxkgmnsm yygaimasmf (ubmufxbemd, eiayuxquou - hkzktnyzqh)
Phase 3
882
(FS MDPI 200 / 12.5 mcg)
hsjckiuwwv(sazvdzelyn) = mzerkhifio pmprirraaq (umyjbxfwrg, vfoxefusrp - tdsbrnumuj)
-
12 Apr 2017
(FS MDPI 100 / 12.5 mcg)
hsjckiuwwv(sazvdzelyn) = ovolhjdujc pmprirraaq (umyjbxfwrg, hnmbnnygji - rjoillasip)
Not Applicable
16
Extra fine HFA formoterol (FM) 12µg
llrhzjmoaz(zlposziqpo): mean difference = 19.46 (95% CI, 7.56 - 31.36), P-Value = 0.003
-
01 Sep 2015
Coarse particle DPI salmeterol (SM) 50µg
Not Applicable
2,103
ddsarcdyau(zqmxdzyzld) = efnczakozh pofpbaulbn (xdpjpgezpl )
Positive
01 May 2015
ddsarcdyau(zqmxdzyzld) = pzcjobedms pofpbaulbn (xdpjpgezpl )
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Regulation

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