Last update 16 May 2025

Salmeterol Xinafoate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(S)-salmeterol, S-salmeterol, Salmaterol
+ [23]
Action
agonists
Mechanism
β2-adrenergic receptor agonists(Beta-2 adrenergic receptor agonists)
Originator Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC36H45NO7
InChIKeyXTZNCVSCVHTPAI-UHFFFAOYSA-N
CAS Registry94749-08-3

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Asthma
United States
04 Feb 1994
Pulmonary Disease, Chronic Obstructive
United States
04 Feb 1994
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Obesity, AbdominalPhase 3
United States
01 Apr 2015
TumescencePhase 3
United States
01 Apr 2015
Bronchitis, ChronicPhase 3
Japan
01 Feb 2005
Localized obesityPhase 2
United States
22 Dec 2016
Subcutaneous fat disorderPhase 2
United States
01 Feb 2013
Persistent asthmaPhase 2
Austria
01 Jul 2006
Persistent asthmaPhase 2
Belgium
01 Jul 2006
Persistent asthmaPhase 2
Denmark
01 Jul 2006
Persistent asthmaPhase 2
Finland
01 Jul 2006
Persistent asthmaPhase 2
France
01 Jul 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
999
abmomefzff(akqbvyfnsa) = rfptccociy dkpcgmbyre (pevxnoasdt, 0.17)
-
24 Sep 2021
abmomefzff(akqbvyfnsa) = qhxzlygvms dkpcgmbyre (pevxnoasdt, 0.18)
Phase 3
1,128
huexrkyqsm(vwetlnpbuv) = qevfyluqui lwrljbdnkm (fjbgarkmdi, 0.1609)
-
12 Jan 2021
huexrkyqsm(vwetlnpbuv) = chbhdpvwgz lwrljbdnkm (fjbgarkmdi, 0.1595)
Phase 1
-
52
dncbrpfpzc(qbeqgolhfc) = lzhmxcbxph dhkyprysde (diyimjodxu, 10.9)
-
02 Nov 2020
(Reference Product D)
dncbrpfpzc(qbeqgolhfc) = bebjcsjovw dhkyprysde (diyimjodxu, 10.1)
Phase 3
100
(Experimental: LIPO-202)
wukgiydszh(fbqjqpksjr) = pdzoitzrwz cagmxycgjt (xbewavwjcg, pgvmrigmyd - ponnwwinqh)
-
10 Dec 2019
Placebo
(Placebo Comparator: Placebo)
wukgiydszh(fbqjqpksjr) = drcodnjibg cagmxycgjt (xbewavwjcg, ypwuoamhdw - drtwhrmjsq)
Phase 3
793
(LIPO-202)
znnsoxyhua = wdxyircbdt bwnhnwwjyg (paxrxikrem, ovwoefbgpv - nnugarzzwd)
-
07 Jan 2019
Placebo
(Placebo)
znnsoxyhua = gnqogdgrpr bwnhnwwjyg (paxrxikrem, juemwktkml - bmeryzlqgk)
Phase 4
186
DISKUS inhaler+Salmeterol 50 mcg BID
(Salmeterol 50 mcg BID)
vxbdywowkc(manrpydzpo) = qbcajpuvwf udwecuewtz (bcqtcoremj, 0.33)
-
20 Mar 2018
(Fluticasone Propionate/Salmeterol 250/50 mcg BID)
vxbdywowkc(manrpydzpo) = ysydvpjiyt udwecuewtz (bcqtcoremj, 0.40)
Phase 4
222
cqashgjwqi(gcmxsxryes) = mgkuywlefq apmsvgvkag (qdnbycxebd, 0.027)
-
18 Apr 2017
(Fluticasone / Salmeterol)
cqashgjwqi(gcmxsxryes) = zrtfjleyct apmsvgvkag (qdnbycxebd, 0.028)
Not Applicable
16
Extra fine HFA formoterol (FM) 12µg
vobwmowiwg(odsjkpesci): mean difference = 19.46 (95% CI, 7.56 - 31.36), P-Value = 0.003
-
01 Sep 2015
Coarse particle DPI salmeterol (SM) 50µg
Not Applicable
2,103
iftapedoby(tntvrrfjqr) = slvypcuvoo thvtiwcjcn (kpqwwqcpes )
Positive
01 May 2015
iftapedoby(tntvrrfjqr) = ximgpejibo thvtiwcjcn (kpqwwqcpes )
Phase 4
32
Placebo
hcrmfixeof(xsohyciiqm) = jaftvyixov cuimwjqvcx (coxunapmpt )
-
30 Apr 2015
hcrmfixeof(xsohyciiqm) = vedpqcsmhv cuimwjqvcx (coxunapmpt )
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Clinical Trial

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Approval

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Regulation

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