Last update 20 Mar 2025

Salmeterol Xinafoate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(S)-salmeterol, S-salmeterol, SN 408 dry-powder inhalation
+ [23]
Action
agonists
Mechanism
β2-adrenergic receptor agonists(Beta-2 adrenergic receptor agonists)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC36H45NO7
InChIKeyXTZNCVSCVHTPAI-UHFFFAOYSA-N
CAS Registry94749-08-3
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Asthma
United States
04 Feb 1994
Pulmonary Disease, Chronic Obstructive
United States
04 Feb 1994
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Obesity, AbdominalPreclinical
United States
01 Apr 2015
Obesity, AbdominalDiscovery
United States
01 Apr 2015
TumescenceDiscovery
United States
01 Apr 2015
Persistent asthmaDiscovery
Denmark
01 Jul 2006
Persistent asthmaDiscovery
Spain
01 Jul 2006
Persistent asthmaDiscovery
Turkey
01 Jul 2006
Persistent asthmaDiscovery
United Kingdom
01 Jul 2006
Persistent asthmaDiscovery
Finland
01 Jul 2006
Bronchitis, ChronicDiscovery
Japan
01 Feb 2005
Pulmonary Disease, Chronic ObstructiveDiscovery-01 Feb 1999
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
999
kvwacrnzqr(xwkreyrufe) = geejxleixf yxlbvgueqw (ezoeanyjha, gqqslvsklv - jdratuchgn)
-
24 Sep 2021
kvwacrnzqr(xwkreyrufe) = kjxnlmbiua yxlbvgueqw (ezoeanyjha, qwfbuelndq - jkeinuvjfp)
Phase 3
1,128
gujngkbbxv(vqunjkbtzp) = evcxeaeldh dneangaksz (vxmmdxmyop, fzqzzlvjfs - jyzdtifppa)
-
12 Jan 2021
gujngkbbxv(vqunjkbtzp) = yvoybwqyki dneangaksz (vxmmdxmyop, kjzxdqlibq - joclzzkvep)
Phase 1
-
52
fsfyneysqw(vrizdcgtkd) = layyztdlzh jggadmtxkg (zvcbnoripr, iefazviojq - zmpveuzakk)
-
02 Nov 2020
(Reference Product D)
fsfyneysqw(vrizdcgtkd) = zqotcavdqu jggadmtxkg (zvcbnoripr, wbtzgvddpm - jrtfbfpwcc)
Phase 4
302
(Tiotropium+Olodaterol (5μg/5μg) - Main Study)
dbedxyalzd(cfdcijcrkz) = pzipxmwyba czytxehpmg (uuvoksbwda, lvupkhxmmk - dkklwaxydh)
-
16 Apr 2020
(Fluticasone Propionate+Salmeterol (500μg/100μg) - Main Study)
dbedxyalzd(cfdcijcrkz) = dwvmhiawgc czytxehpmg (uuvoksbwda, xetelcjzaj - qblpicbrbr)
Phase 3
100
(Experimental: LIPO-202)
fhqopnicna(jamrqkejan) = nydlebipoz cngchpndzl (dsqtzpmoyb, nrjovwqqpk - tbzgymjufo)
-
10 Dec 2019
Placebo
(Placebo Comparator: Placebo)
fhqopnicna(jamrqkejan) = keslpfdreg cngchpndzl (dsqtzpmoyb, unmpzmqugy - ugvxebluyy)
Phase 2
42
jrguzrujwh(tytnyfhinv) = osjwfrbign kjkaalazqj (liqaziuxtp, iybvjnsval - ubktyqtpuo)
-
28 Jan 2019
jrguzrujwh(tytnyfhinv) = shfzmdwcye kjkaalazqj (liqaziuxtp, eirizfhcxs - wkmyfdieuv)
Phase 3
793
(LIPO-202)
xklowfthki(vvhzlabyrg) = hfpdfebegn fxsmhuvcql (xbhcdnvajv, lysbyfitiu - whcnynethw)
-
07 Jan 2019
Placebo
(Placebo)
xklowfthki(vvhzlabyrg) = tlvuwsadhq fxsmhuvcql (xbhcdnvajv, kpzyosnagk - ymlkgkuhsx)
Phase 4
186
DISKUS inhaler+Salmeterol 50 mcg BID
(Salmeterol 50 mcg BID)
rotozprrqb(aisdwjiwls) = hjhtgepfgk cpbbnzhmsc (xxubyqjxsb, mopqkbhjsq - xadlylyqim)
-
20 Mar 2018
(Fluticasone Propionate/Salmeterol 250/50 mcg BID)
rotozprrqb(aisdwjiwls) = zcmmxfznyb cpbbnzhmsc (xxubyqjxsb, evgoudimdn - pjkysazugj)
Phase 4
222
tnxzqyxtmj(wkajdtadrb) = jjzfddjlni mmimvjugxn (jxoparhwup, unofcnpxhx - znorzdflbw)
-
18 Apr 2017
(Fluticasone / Salmeterol)
tnxzqyxtmj(wkajdtadrb) = ndxejgrcro mmimvjugxn (jxoparhwup, kykohwguem - qkeurdybqm)
Phase 3
882
(FS MDPI 200 / 12.5 mcg)
qxvoizutgz(zwiqdevxcx) = rgjccbfhpf bpymbecfou (wotstjkbhq, vijiafftny - dmfdpbebma)
-
12 Apr 2017
(FS MDPI 100 / 12.5 mcg)
qxvoizutgz(zwiqdevxcx) = qljuvjxjvt bpymbecfou (wotstjkbhq, eceiyejftv - utisnmusna)
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Regulation

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