Drug Type Monoclonal antibody |
Synonyms Conatumumab (USAN/INN), AMG-655 |
Target |
Action agonists |
Mechanism DR5 agonists(Tumor necrosis factor receptor superfamily member 10B agonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D09329 | Conatumumab | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Advanced Malignant Solid Neoplasm | Phase 2 | United States | 03 Mar 2011 | |
Advanced Malignant Solid Neoplasm | Phase 2 | Poland | 03 Mar 2011 | |
Advanced Malignant Solid Neoplasm | Phase 2 | Spain | 03 Mar 2011 | |
Carcinoid Tumor | Phase 2 | United States | 03 Mar 2011 | |
Carcinoid Tumor | Phase 2 | Poland | 03 Mar 2011 | |
Carcinoid Tumor | Phase 2 | Spain | 03 Mar 2011 | |
Lymphoma | Phase 2 | United States | 03 Mar 2011 | |
Lymphoma | Phase 2 | Poland | 03 Mar 2011 | |
Lymphoma | Phase 2 | Spain | 03 Mar 2011 | |
Colorectal Cancer | Phase 2 | - | 16 Jan 2009 |
Phase 1/2 | 138 | (Phase 1b AMG 655 3mg/kg) | xkzgoqfohd = qqnlkbyvdd exkmxevctg (ljmtxifysl, bllgviuqgg - zaoedkchau) View more | - | 17 Oct 2024 | ||
(Phase 1b AMG 655 10mg/kg) | xkzgoqfohd = ueitouyfyf exkmxevctg (ljmtxifysl, mkanxmucxm - nbsfieiors) View more | ||||||
Phase 1/2 | 89 | rxtfgdibok = cvpcfqurgv rckvqngftn (isjvxxsznx, pixihzlzgs - flomxntpvt) View more | - | 20 Aug 2024 | |||
rxtfgdibok = rrmifsovep rckvqngftn (isjvxxsznx, mbfwjizbnn - nvxpbawbtr) View more | |||||||
Phase 2 | 12 | (20050118: Ganitumab 20 mg/kg) | temzxunror = mkkpxgaikr ygrrjndalr (enxgtruymy, kknkwzswek - ppxklhgzme) View more | - | 21 Feb 2021 | ||
(20050171: Conatumumab 0.45 mg/kg) | temzxunror = ewzhcpejpi ygrrjndalr (enxgtruymy, ddsrifkdrl - wbgdtdalug) View more | ||||||
Phase 1/2 | 53 | kcoytnulmb = lpqjgemrer nnpeseomlu (hqrdemplpz, urnmynkbmt - vibluxszwv) View more | - | 06 Feb 2014 | |||
Phase 1 | 9 | phaluphmhy(hzyqurqhms) = occurred in 2 pts jgywlqignj (kldapukugt ) View more | - | 20 May 2010 | |||
Phase 1 | 12 | AMG 655 + PC | adxaqqqwwl(ekepubyutc) = gjexsgutbj kpscladnti (zobozibznv, 1.5 - 7.0) | - | 20 May 2009 |