Drug Type Small molecule drug |
Synonyms Ketotifen fumarate (JP17/USAN), Ketotifen Fumarate Nasal Drops, Ketotifen Fumarate Nasal Spray + [15] |
Target |
Mechanism H1 receptor antagonists(Histamine H1 receptor antagonists) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date CH (03 May 1979), |
Regulation- |
Molecular FormulaC23H23NO5S |
InChIKeyYNQQEYBLVYAWNX-WLHGVMLRSA-N |
CAS Registry34580-14-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01332 | Ketotifen Fumarate | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Eczema | JP | 30 Apr 1986 | |
Pruritus | JP | 30 Apr 1986 | |
Urticaria | JP | 30 Apr 1986 | |
Asthma | CH | 03 May 1979 | |
Chronic Urticaria | CH | 03 May 1979 | |
Conjunctivitis, Allergic | CH | 03 May 1979 | |
Dermatitis, Atopic | CH | 03 May 1979 | |
Rhinitis, Allergic | CH | 03 May 1979 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Seasonal allergic conjunctivitis | Phase 3 | US | 18 Nov 2022 |
Not Applicable | - | crmuhuygmk(brxtfxvlkz) = qpzrmjdumu jrlpzijxrb (kqiuiaosuy ) | Positive | 01 Jun 2021 | |||
Phosphate buffer saline eye drops | jhnlfvuevl(vzofxpjsgi) = nwdcerqrht rwawzeipjh (cmgocfwbdf ) | ||||||
Not Applicable | Peanut Hypersensitivity eosinophilia | 6 | chhuipepwr(ulhylacdmc) = 3 anaphylactic reactions occurred: day-1 placebo patient at 50mg dose (gastrointestinal, cutaneous); day-5 treatment patient at 50mg dose, occurred post exercise, (gastrointestinal, cutaneous, respiratory); day-6 placebo patient at 12mg dose, associated with fever, (gastrointestinal, cutaneous, respiratory), epinephrine was given and patient withdrew from study zsirpnlpkh (zncdkqxlcr ) View more | Positive | 01 Feb 2012 | ||
Placebo | |||||||
Not Applicable | 99 | Epinastine HCl 0.05% | xwreduzbjw(hrnjmqpysx) = Three (5.9%) epinastine patients and 7 (14.6%) ketotifen patients experienced adverse events. Treatment-related sleep disorder was reported for 2 ketotifen-treated patients, but was not found in epinastine-treated patients. czijxdkjsn (qvxioevyri ) | - | 01 May 2004 | ||
Not Applicable | Conjunctivitis, Allergic HLA-DR+ | CD29+ | eotaxin+ | 19 | xewfccqerp(wouzjlovlf) = exfweoitqv bdxxuewxop (bhgirntvng ) View more | Positive | 01 May 2003 | ||
Not Applicable | 92 | lbptdgevux(szksjhuznb) = uztdwhhnrg tznokqyngo (bhibluapkl ) | - | 01 May 2003 | |||
Olopatadine HCl 0.1% | lbptdgevux(szksjhuznb) = minpyodslj tznokqyngo (bhibluapkl ) | ||||||
Not Applicable | - | - | cuxrdwlxia(bwaikddxhq) = jchlnzkleu fkuepbcibo (vaddlfbmlp ) | Positive | 22 Oct 2000 |