A gas chromatog. method for the determination of residual organic solvents in prasugrel was developed. The samples were injected into DB624 capillary column and analyzed with FID detector using acetone as the internal standard The linear ranges of ethanol, Et ether, dichloromethane, Et acetate were 50-800 mg·L-1 (r=0.9995), 50-800 mg·L-1 (r=0.9991), 6-96 mg·L-1 (r=0.9994), 50-800 mg·L-1 (r=0.9996) resp. The recoveries were 99.51%, 98.97%, 99.25%, 99.32%; RSD 1.25%, 1.14%, 1.23%, 1.05% (n=9) resp. The method is simple, accurate and sensitive with good reproducibility. It can be used for the determination of the residual organic solvents in prasugrel.