Delving into the Latest Updates on Wuhan Wuyao Pharmaceutical Co., Ltd. with Synapse

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Neoplasms

Nervous System Diseases

Small molecule drug

Disease domain score

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Technology Platform

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Disease Domain	Count

Neoplasms	2
Nervous System Diseases	2
Infectious Diseases	2
Hemic and Lymphatic Diseases	1
Immune System Diseases	1

Top 5 Drug Type	Count

Small molecule drug	5

Top 5 Target	Count

rpoB(DNA-directed RNA polymerase beta chain)	1
α1A-AR x α1B-AR	1
DNA	1

The production of metronidazole is generally performed by batch tank reaction process with long-time and high-exhausting, accompanying with low conversion of the starting material 2-methyl-5-nitroimidazole and serious side-reaction of ethylene epoxide.A lot of waste acid and salt are generated in the productive process.Based on the original material and solvents, the reaction conditions were explored in single tube by the aid of a new tubular reactor.The results showed that the reaction could be quickly completed in 7-10 min at 90-95 °C.The reaction time was shortened by more than 30 times and the conversion of the nitro-compound was increased by 1.5 times.It suggests that a continuous production can be realized, and provides a tech. basis for the industrialization of metronidazole by tubular reaction.

RSC Advances

Adsorption and desorption of flavonoids on activated carbon impregnated with different metal ions

Article

Author: Huang, Jingdan ; Deng, Changyong ; Lu, Li ; Liu, Zhimei ; Cao, Shuang ; Jiang, Yukai ; Liu, Ziwei ; Li, Zhexuan

The application for the flavonoids seperation of the activated carbon impregnated with metal ions.

Guangzhou Huagong

A new method of synthesized dibenzothiazole disulfide

Author: Wang, Yin ; Wang, Xiu-jun ; Di, Zhen-xue ; Chen, Long ; Liang, Hua-liang ; Yang, Ming-li

The dibenzothiazyl disulfide (accelerator DM) was first synthesized with 2-mereapto benzothiazole (accelerator M), fuming nitric acid and glacial acetic acid by one step.The effects of the reactions temperature, the reaction time, and the mass ration yield were discussed.The optimal reaction conditions established were that the reaction temperature was 20°C, the ration of accelerator and glacial acetic was 1:20, the reaction was time was 40 min, and the ration of fuming nitric acid and accelerator M was 2:1.Under above conditions, the yield of accelerator DM was 92.4% and the m.p. was 169.6-171.0°C.

100 Deals associated with Wuhan Wuyao Pharmaceutical Co., Ltd.

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100 Translational Medicine associated with Wuhan Wuyao Pharmaceutical Co., Ltd.

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Pipeline

Pipeline Snapshot as of 21 Feb 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Approved

5

1

Other

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Current Projects

Drug(Targets)	Indications	Global Highest Phase

Methoxsalen ( DNA )	Vitiligo More	Approved
Pirenoxine	Cataract More	Approved
Norepinephrine Bitartrate ( α1A-AR x α1B-AR )	Hypotension More	Approved
Ethambutol Hydrochloride ( rpoB )	Tuberculosis More	Approved
Aminophenazone	Pain More	Approved