Delving into the Latest Updates on Haerbin Taihua Pharmaceutical Co. Ltd. with Synapse

Overview

Tags

Respiratory Diseases

Infectious Diseases

Otorhinolaryngologic Diseases

Small molecule drug

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

Disease Domain	Count

Infectious Diseases	2
Endocrinology and Metabolic Disease	1

Top 5 Drug Type	Count

Small molecule drug	3

Top 5 Target	Count

Bacterial DNA gyrase	1
A1R x A2aR x COX x DRDs x H1 receptor x NMDA receptor	1

主要研究目的：通过空腹/餐后试验研究，考察中国健康研究参与者在空腹/餐后条件下单次口服受试制剂布洛芬片（规格：0.2 g，哈尔滨泰华药业股份有限公司研发）与参比制剂布洛芬片（商品名：Motrin IB ®，规格：0.2 g，Johnson and Johnson Consumer Inc McNeil Consumer Healthcare Division持证的）后的体内药代动力学特征，评价两制剂的生物等效性。次要研究目的：评价单次口服布洛芬片 0.2 g 受试制剂及参比制剂在中国健康研究参与者中的安全性。

[Translation]

Primary study objective: To investigate the in vivo pharmacokinetic characteristics of the test preparation ibuprofen tablets (specification: 0.2 g, developed by Harbin Taihua Pharmaceutical Co., Ltd.) and the reference preparation ibuprofen tablets (trade name: Motrin IB ®, specification: 0.2 g, licensed by Johnson and Johnson Consumer Inc McNeil Consumer Healthcare Division) after a single oral administration of the test preparation ibuprofen tablets (specification: 0.2 g, developed by Harbin Taihua Pharmaceutical Co., Ltd.) in Chinese health research participants under fasting/postprandial conditions, and to evaluate the bioequivalence of the two preparations. Secondary study objective: To evaluate the safety of a single oral administration of 0.2 g of the test preparation and the reference preparation of ibuprofen tablets in Chinese health research participants.

Start Date-

Sponsor / Collaborator

Haerbin Taihua Pharmaceutical Co. Ltd.

100 Clinical Results associated with Haerbin Taihua Pharmaceutical Co. Ltd.

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0 Patents (Medical) associated with Haerbin Taihua Pharmaceutical Co. Ltd.

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2

Literatures (Medical) associated with Haerbin Taihua Pharmaceutical Co. Ltd.

Heilongjiang Yiyao

Study on extraction technique and purification technique of Rhizoma chuanxiong in Dachuanxiong hydrochloride for injection

Author: Zhu, Li-di ; Liu, Tian-fu ; Shen, Li ; Xu, Yan-li

The objective was to study extraction technique and purification technique of Rhizoma Chuanxiong.Orthogonal experiment design and single factor tests were used for optimizing the extraction and purification technol. of Rhizoma Chuanxiong by measuring transition probability.Rhizoma chuanxiong was reflux-extracted with water, and purified with the methods of ethanol deposition, 20% calcium hydroxide-sulfuric acid-ethanol and water deposition.Transference rate of ferulic acid could arrive at 77.01%, and the impurities such as protein, oxalate, tannin and resin were all removed.

Zhongguo Haiyang Yaowu

Study on biodegradability of hydroxypropylated chitosan with various degrees of substitution

Author: Qi, Qiupeng ; Hong, Sui ; Liu, Tianfu ; Wang, Zhongyan

The biocompatibility of hydroxypropylated chitosan film with diverse degrees of substitution is studied, and the effect of the degrees of substitution to biodegradability is examinedThe in vitro biodegradability of the film was determined by the incubation with lysozyme, and the in vivo biodegradability of the film was determined by the tests on mice.The hydroxypropylated chitosan shows good biocompatibility, and the biodegradation of hydroxypropylated chitosan film increases with increasing the degree of substitution.Lysozyme can promote the biodegradation

100 Deals associated with Haerbin Taihua Pharmaceutical Co. Ltd.

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100 Translational Medicine associated with Haerbin Taihua Pharmaceutical Co. Ltd.

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Pipeline

Pipeline Snapshot as of 07 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Approved

3

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Current Projects

Drug(Targets)	Indications	Global Highest Phase

Oyster Shell Calcium	Hypocalcemia More	Approved
Acetaminophen/Amantadine Hydrochloride/Artificial bezoar/Caffeine/Chlorphenamine Maleate ( A1R x A2aR x COX x DRDs x H1 receptor x NMDA receptor )	Common Cold More	Approved
Pipemidic Acid Hydrate ( Bacterial DNA gyrase )	Bacterial Infections More	Approved