Last update 08 May 2025

Lead Chemical Co., Ltd.

Private Company|1987|Tokyo-to, Japan|
www.leadchem.co.jp

Overview

Tags

Nervous System Diseases
Immune System Diseases
Respiratory Diseases
Small molecule drug

Disease domain score
A glimpse into the focused therapeutic areas
Technology Platform
Most used technologies in drug development
Targets
Most frequently developed targets
Disease DomainCount
Immune System Diseases1
Infectious Diseases1
Nervous System Diseases1
Top 5 Drug TypeCount
Small molecule drug1
Top 5 TargetCount
COXs(Cyclooxygenases)1

Related

2
Drugs associated with Lead Chemical Co., Ltd.
Loxoprofen Sodium Hydrate
Target
COXs
Mechanism
COX inhibitors
Active Org.
Overseas Pharmaceuticals Ltd.Overseas Pharmaceuticals Ltd. [+7]
Originator Org.
Daiichi Sankyo Co., Ltd.Daiichi Sankyo Co., Ltd.
Active Indication
Pain, Postoperative [+14]
Inactive Indication
Myalgia [+1]
Drug Highest PhaseApproved
First Approval Ctry. / Loc.
Japan
First Approval Date01 Mar 1986
LCY-018
Target
AT1R
Mechanism
AT1R antagonists
Active Org.-
Originator Org.
Lead Chemical Co., Ltd.
Active Indication-
Inactive Indication
Hypertension
Drug Highest PhasePending
First Approval Ctry. / Loc.-
First Approval Date-
5
Clinical Trials associated with Lead Chemical Co., Ltd.
NCT02602353
/ CompletedPhase 2
A Phase 2, Randomized, Double-Blind, Parallel-Group and Placebo-Controlled Pilot Study to Assess the Safety and Efficacy of a New Pain Patch Versus Placebo and No Treatment for the Treatment of Delayed Onset Muscle Soreness (DOMS)
ISRCTN10182003
/ CompletedNot Applicable
A randomized, controlled, double blind, double dummy clinical trial to evaluate the safety and efficacy of Loxoprofen Sodium Cataplasm ointment (Loxonin®PAP100mg) against swelling and pain caused by trauma
ISRCTN40097939
/ CompletedPhase 2
A randomized, controlled, double blind, double dummy clinical trial to evaluate the safety and efficacy of Loxoprofen Sodium Cataplasm Ointment (Loxonin®PAP100mg) against knee osteoarthritis
100 Clinical Results associated with Lead Chemical Co., Ltd.
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0 Patents (Medical) associated with Lead Chemical Co., Ltd.
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11
Literatures (Medical) associated with Lead Chemical Co., Ltd.
01 Jan 2019Proceedings for Annual Meeting of The Japanese Pharmacological Society
Decreased hippocampal GLP-1 and the shift in the circadian rhythms are induced by long-term exposure of isoflurane with surgery in mice
01 Jan 2019Proceedings for Annual Meeting of The Japanese Pharmacological Society
Isoflurane-induced postoperative cognitive impairment and enhanced abnormal social interaction are associated with decrease in hippocampal dopamine D<sub>2</sub> receptor in mice
01 Jan 2008Chemical and Pharmaceutical BulletinQ4 · MEDICINE
New Chromane Derivatives Isolated from the Brown Alga, Sargassum micracanthum
Q4 · MEDICINE
100 Deals associated with Lead Chemical Co., Ltd.
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100 Translational Medicine associated with Lead Chemical Co., Ltd.
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Pipeline

Pipeline Snapshot as of 24 Jun 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3
Approved
1
1
Other
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Current Projects

Drug(Targets)IndicationsGlobal Highest Phase
Loxoprofen Sodium Hydrate
 ( COXs )		Pain
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Approved
LCY-018
 ( AT1R )		Hypertension
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Pending
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Profit

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