Last update 08 May 2025

Loxoprofen Sodium Hydrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
LX-A, LX-P, Loxonin Pap
+ [51]
Target
Action
inhibitors
Mechanism
COX inhibitors(Cyclooxygenases inhibitors)
Inactive Indication
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
Japan (01 Mar 1986),
RegulationPriority Review (China)
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Structure/Sequence

Molecular FormulaC15H20NaO4
InChIKeyNGHFIMBWFYJBHQ-UHFFFAOYSA-N
CAS Registry226721-96-6
View All Structures (3)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pain, Postoperative
South Korea
03 Apr 2024
Inflammation
Japan
01 Mar 1986
Pain
Japan
01 Mar 1986
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pain, PostoperativePhase 3
China
25 Mar 2024
Pain, PostoperativePhase 3
China
25 Mar 2024
Post procedural inflammationPhase 3
China
25 Mar 2024
Post procedural inflammationPhase 3
China
25 Mar 2024
Ocular inflammationPhase 2
China
30 Dec 2022
Ocular inflammationPhase 2
China
30 Dec 2022
Osteoarthritis, KneePreclinical
China
10 Apr 2017
MyalgiaPreclinical
United States
01 Oct 2015
PainPreclinical
Brazil
01 Oct 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
-
39
(Transdermal Estradiol Plus Spironolactone)
scczyvjgvw(jcxlunawcq) = qwglpkgpnz hejkisdxpo (qliidplufu, bsfdwjpiwd - pllgjxkmmb)
-
26 Nov 2024
Hormone Profile+Spironolactone+Daily Sublingual Tablet
(Daily Sublingual Estradiol Plus Spironolactone)
scczyvjgvw(jcxlunawcq) = mxwagaonmr hejkisdxpo (qliidplufu, yxqikjpmqw - ospfiznrav)
Not Applicable
451
(People living with HIV)
ysrolnkmqr(skgcsmtnhk) = zgpconubgo klhafnawps (jefwnxgfnj, 5.1 - 36)
-
01 Jan 2022
Phase 2
47
hbrxiqvzbd(umssupdqhz) = qqmwpbzowf eqfubftbvo (eqxvvgyogo, hikykumcaa - sofzdmpdhq)
-
09 Sep 2019
hrIL-2 placebo+Loxoprofen+Folic Acid+MTX
(Placebo Comparator)
hbrxiqvzbd(umssupdqhz) = albsjyygin eqfubftbvo (eqxvvgyogo, idmbhtbntn - gjddoesmjf)
Phase 3
80
eoinfcbcoj(kzqoqlknsy) = xxykjrexqg pgnsbsntsf (rdecpmgjdu, zabhgbyxzr - guuaahhysu)
-
20 Jul 2018
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Regulation

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