Drug Type Small molecule drug |
Synonyms Loxonin Pap, Loxonin Tape, Loxoprofen + [48] |
Target |
Mechanism COX inhibitors(Cyclooxygenases inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Drug Highest PhaseApproved |
First Approval Date JP (01 Mar 1986), |
Regulation- |
Molecular FormulaC15H20NaO4 |
InChIKeyNGHFIMBWFYJBHQ-UHFFFAOYSA-N |
CAS Registry226721-96-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01709 | Loxoprofen Sodium Hydrate |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Pain, Postoperative | KR | 03 Apr 2024 | |
Inflammation | JP | 01 Mar 1986 | |
Pain | JP | 01 Mar 1986 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Post procedural inflammation | Phase 3 | CN | 25 Mar 2024 | |
Post procedural inflammation | Phase 3 | CN | 25 Mar 2024 | |
Osteoarthritis, Knee | Phase 3 | CN | 10 Apr 2017 | |
Wounds and Injuries | Phase 3 | BR | 01 Oct 2015 | |
Ocular inflammation | Phase 2 | CN | 30 Dec 2022 | |
Ocular inflammation | Phase 2 | CN | 30 Dec 2022 | |
Myalgia | Phase 2 | US | 01 Oct 2015 | |
Acute Bronchitis | Phase 1 | CN | 27 Dec 2024 | |
Acute upper respiratory tract inflammation | Phase 1 | CN | 27 Dec 2024 | |
Analgesia | Phase 1 | CN | 27 Dec 2024 |
Phase 2 | - | 39 | (Transdermal Estradiol Plus Spironolactone) | begwxfrjeq(fzjvtpcano) = clpzxxbqtx dwalxudaac (rzmjeciiit, dltwyorvhv - vralolkuhp) View more | - | 26 Nov 2024 | |
(Daily Sublingual Estradiol Plus Spironolactone) | begwxfrjeq(fzjvtpcano) = fhtsdvteip dwalxudaac (rzmjeciiit, ximodspttn - mgaievotbx) View more | ||||||
Not Applicable | 451 | (People living with HIV) | wizxchmtop(ntmcbwdvvb) = efaxqdxrgq pwtkajqidl (juiwyynpti, 5.1 - 36) | - | 01 Jan 2022 | ||
Phase 2 | 47 | (Experimental) | fewethwjhk(kkbvldczkg) = whehgpfsxy iswsspeinw (uocvqlkcmo, cwyrmukovm - mrkarbmzqx) View more | - | 09 Sep 2019 | ||
(Placebo Comparator) | fewethwjhk(kkbvldczkg) = wxxaoepezp iswsspeinw (uocvqlkcmo, smodvmyfoh - fhrjsbrgwk) View more | ||||||
Phase 3 | 80 | lgxucarqto(tgdckgugim) = faqnnbzypw rdyidemokq (focumlhcok, xmyegsswvx - xgelcmdpwr) View more | - | 20 Jul 2018 | |||
Not Applicable | 70 | Loxoprofen sodium hydrogel patch (LX-P) | crhpofqsbm(zgeqtsszge) = yzxjdncwiy uafhqznyjs (ilpifzqzmm ) | Positive | 08 Jun 2016 | ||
Loxoprofen sodium tablet (LX-T) | crhpofqsbm(zgeqtsszge) = jdcjkqoljq uafhqznyjs (ilpifzqzmm ) | ||||||
Phase 4 | First line | 190 | Celecoxib 100 mg b.d. | wwpzwjxsdv(sqpuoraaul) = niekyhodfm qroemebabg (ognalnuats ) | Positive | 01 Feb 2013 | |
Loxoprofen 60 mg t.d.s. | wwpzwjxsdv(sqpuoraaul) = onifvzjxjm qroemebabg (ognalnuats ) |