Shandong Chengchuang Pharmaceutical R&D Co., Ltd.

To evaluate the effectiveness and safety of this oral solution for bowel cleansing before colonoscopy in adult patients

A human pharmacokinetic study was conducted using cycloserine capsules provided by Beijing Yuekang Kaiyue Pharmaceutical Co., Ltd. at three single doses: low, medium, and high. The time course of cycloserine blood concentration in subjects was observed and the pharmacokinetic characteristics of absorption, distribution, metabolism, and excretion in Chinese people were evaluated.

Healthy male volunteers were used as test subjects. A randomized self-crossover control trial method was used to evaluate the bioequivalence of cycloserine capsules provided by Beijing Yuekang Kaiyue Pharmaceutical Co., Ltd. and cycloserine capsules (trade name: Seromycin?) produced by The Chao Center for Industrial Pharmacy & Contract Manufacturing. The purpose was to provide a basis for clinical medication, calculate the relative bioavailability of the test preparation, and compare the bioequivalence of the two preparations.