Shanghai Bao Pharmaceuticals Co., Ltd.

主要目的：评估KJ103治疗抗GBM病患者的初步疗效。 次要目的：评估KJ103治疗抗GBM病患者的安全性、药代动力学（PK）特征、药效动力学（PD）特征、免疫原性。

This is a single-centre, randomised, open-label, single-dose, two-cycle, double-crossover study to compare the pharmacokinetics of SJ04 and Ovidrel® in healthy female subjects. Received a single subcutaneous injection administration of SJ04 Injection or Ovidrel®, both administered at a dose of 250 μg, once per cycle, and cross-administered after a washout period.

An open-label, single-arm Phase II study to evaluate the preliminary efficacy, safety, pharmacokinetics, pharmacodynamics and immunogenicity of KJ103 in patients with anti-GBM disease.