AceLink Therapeutics announced the initiation of AL01211 dosage for the first patient in its Phase 2 study for Fabry disease in China.

Nimbus Therapeutics, LLC has now shared preliminary findings from its ongoing Phase 1/2 trial of NDI-101150, an HPK1 small-molecule inhibitor.

Immunology firm, INmune Bio, Inc. will present its findings on the use of INB03 in managing high-risk MUC4 expressing HER2+ breast cancer. INB03 is a dominant-negative suppressor of soluble TNF.

Sarepta Therapeutics, Inc. shared initial results from EMBARK, a global Phase 3 trial evaluating ELEVIDYS (delandistrogene moxeparvovec-rokl) in Duchenne muscular dystrophy patients aged 4-7.

SparX Biopharmaceutical Corp. happily announces FDA approval of its IND application for SPX-303, a key development in powered antibody therapies and a leading anti-LILRB2/PD-L1 bispecific antibody drug candidate.

Volastra Therapeutics has begun dosing the first participant in a Phase I/II clinical trial of VLS-1488, which, along with sovilnesib, forms their portfolio of unique KIF18A inhibitors designed to treat solid tumors with high chromosomal instability.

At the 16th Clinical Trials on Alzheimer's Disease convention in Boston on October 27, 2023, clinical-phase biotech firm Allyx Therapeutics revealed findings from their Phase 1a study of ALX-001, their orally administered, pioneering, highly-selective, synapse-focused, disease-modifying neurodegenerative treatment.

Clinical trial phase III of RUBY, using Jemperli (dostarlimab) with chemotherapy for treating endometrial cancer, successfully reaches endpoint in enhancing overall patient survival rate.

NovelMed Therapeutics kicks off its Phase II trial for untreated Paroxysmal Nocturnal Hemoglobinuria (PNH) patients. The primary investigation will be on the anti-Bb antibody NM8074 through a comprehensive study, aiming to evaluate its safety and efficiency in PNH patients.

Novartis published positive early results from the critical Phase III ALIGN trial midpoint evaluation, studying atrasentan, an oral ERA for treating people with IgA nephropathy.

Innovent reports substantial weight reduction, several metabolic advantages, and a good safety record with a higher dose of 9 mg Mazdutide (IBI362) following a 48-week trial in phase 2 study for obesity.

Merck KGaA, Darmstadt, has formed a strategic partnership with Jiangsu Hengrui Pharmaceuticals Co. Ltd. It holds a global exclusive license to develop, manufacture, and distribute Hengrui’s advanced PARP1 trapping inhibitor HRS-1167.