Pharmaceutical Insights
Navigate pharmaceutical trends with our insights on targets, institutional pipelines, clinical advances, and new drugs.
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Recent blog posts
10xBio's Phase 2b Trial Suggests Improved Submental Fat Treatment
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3 min read
10xBio's Phase 2b Trial Suggests Improved Submental Fat Treatment
15 March 2024
10xBio Reveals Interim Phase 2b Trial Outcomes Indicate Enhanced Effectiveness of New Treatment in Submental Fat Reduction.
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Hypertension and Metabolic Syndrome Candidate Target: Endothelin Receptor
Hypertension and Metabolic Syndrome Candidate Target: Endothelin Receptor
15 March 2024
Recently, a collaborative research effort involving multiple German scientific institutions has revealed that the endothelin B receptor (ETB) plays a crucial role in controlling metabolic syndrome brought on by high-calorie diets.
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Advancing the onCARlytics Study: Exploring Combined Therapies in Early-Stage Solid Cancers
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3 min read
Advancing the onCARlytics Study: Exploring Combined Therapies in Early-Stage Solid Cancers
15 March 2024
Initial stage of the onCARlytics study focusing on solid cancers moves forward to explore combined therapeutic approaches.
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Optimize Your Synapse Experience: A Step-by-Step Guide to Searching Simvastatin
Drug Insights
2 min read
Optimize Your Synapse Experience: A Step-by-Step Guide to Searching Simvastatin
15 March 2024
Simvastatin, a diminutive molecular entity, functions as an HMG-CoA reductase enzyme inhibitor, which is accountable for the synthesis of cholesterol in the hepatic tissue.
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J&J Seeks FDA Approval for TREMFYA® in Treating Adult Ulcerative Colitis
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3 min read
J&J Seeks FDA Approval for TREMFYA® in Treating Adult Ulcerative Colitis
15 March 2024
Johnson & Johnson has filed a supplementary application with the FDA for the authorization of TREMFYA® (guselkumab) aimed at treating moderate to severe ulcerative colitis in adults.
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Several bispecific antibodies targeting GPCRs
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5 min read
Several bispecific antibodies targeting GPCRs
15 March 2024
Bispecific antibodies (bsAbs) possess unique advantages due to their ability to simultaneously target two distinct antigens, which helps to enhance the immune system's recognition and killing of tumor cells.
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Domain Therapeutics and Chime Biologics Ink Deal to Advance CCR8 Antibody for Cancer Immunotherapy
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3 min read
Domain Therapeutics and Chime Biologics Ink Deal to Advance CCR8 Antibody for Cancer Immunotherapy
15 March 2024
Domain Therapeutics and Chime Biologics have entered into a production deal to push forward a new CCR8-targeting antibody for use in treating cancer through immunotherapy.
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The Synapse User's Toolkit: Tips for Searching Glipizide
Drug Insights
2 min read
The Synapse User's Toolkit: Tips for Searching Glipizide
15 March 2024
Glipizide, a small yet powerful drug from Pfizer Inc., effectively combats hyperglycemia and type 2 diabetes.
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MRT-8102 Preclinical Trials: Exploring Monte Rosa's Innovative NEK7-Targeted Molecular Glue Degrader
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3 min read
MRT-8102 Preclinical Trials: Exploring Monte Rosa's Innovative NEK7-Targeted Molecular Glue Degrader
15 March 2024
Monte Rosa Therapeutics has commenced preclinical trials for its novel compound MRT-8102, a pioneering NEK7-targeted molecular glue degrader with additional capabilities of impeding the NLRP3/IL-1β signaling cascade.
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Tegileridine vs Oliceridine: Comparison of New Analgesic Drugs Targeting Opioid Receptors
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7 min read
Tegileridine vs Oliceridine: Comparison of New Analgesic Drugs Targeting Opioid Receptors
15 March 2024
In January, Jiangsu Hengrui Pharmaceuticals' Tegileridine Fumarate injection, for treating moderate to severe post-op abdominal pain, was approved in China.
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FDA Greenlights Aprea's Novel WEE1 Kinase Inhibitor APR-1051 for Cancer Trial
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3 min read
FDA Greenlights Aprea's Novel WEE1 Kinase Inhibitor APR-1051 for Cancer Trial
15 March 2024
Aprea Therapeutics reveals it has received FDA authorization for its investigational new drug, APR-1051, a novel WEE1 kinase blocker targeting cancers with high Cyclin E levels.
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Unlock the Power of Synapse: A Guide to Searching Hydrocortisone
Drug Insights
2 min read
Unlock the Power of Synapse: A Guide to Searching Hydrocortisone
15 March 2024
Hydrocortisone, a diminutive yet powerful molecule, is renowned for its aptitude to function as a glucocorticoid receptor (GR) agonist, thereby stimulating the GR.
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